Evidence map›Paper›PMID 36339175›Full record

Observational studyFrontiers in public health2022

Health-related quality of life in persons post-COVID-19 infection in comparison to normative controls and chronic pain patients.

Maarten Moens, Rui V Duarte, Ann De Smedt, Koen Putman, Jonas Callens, Maxime Billot, Manuel Roulaud, Philippe Rigoard, Lisa Goudman

Registry-linked trialOpen access · goldAbstract readObservational Study
In one paragraph

Observational study in Frontiers in public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04912778 (Profiling of Post Covid-19 Infection Patients), which is not on this map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04912778 completednot on this map

Profiling of Post Covid-19 Infection Patients: an Online Survey

TypeobservationalSponsorMoens MaartenRan2021 to 2021Enrolled567ConditionsCovid19ArmsFilling in an online survey
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
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  7. One-year trajectories of physical and mental health-related quality of life, fatigue and dyspnoea in COVID-19 survivors.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
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  11. Review
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  15. A longitudinal prospective cohort study of health-related quality of life assessment in outpatient adults with post-COVID-19 conditions.Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2024
    Article
  16. Article
  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 3 countries.

Maarten MoensSTIMULUS Research Group (reSearch and TeachIng neuroModULation Uz bruSsel), Vrije Universiteit Brussel, Brussels, Belgium.
Rui V DuarteLiverpool Reviews and Implementation Group, University of Liverpool, Liverpool, United Kingdom.
Ann De SmedtSTIMULUS Research Group (reSearch and TeachIng neuroModULation Uz bruSsel), Vrije Universiteit Brussel, Brussels, Belgium.
Koen PutmanDepartment of Public Health (GEWE), Faculty of Medicine and Pharmacy, Interuniversity Centre for Health Economics Research (I-CHER), Vrije Universiteit Brussel, Brussels, Belgium.
Jonas CallensSTIMULUS Research Group (reSearch and TeachIng neuroModULation Uz bruSsel), Vrije Universiteit Brussel, Brussels, Belgium.
Maxime BillotPRISMATICS Lab (Predictive Research in Spine/Neuromodulation Management and Thoracic Innovation/Cardiac Surgery), Poitiers University Hospital, Poitiers, France.
Manuel RoulaudPRISMATICS Lab (Predictive Research in Spine/Neuromodulation Management and Thoracic Innovation/Cardiac Surgery), Poitiers University Hospital, Poitiers, France.
Philippe RigoardPRISMATICS Lab (Predictive Research in Spine/Neuromodulation Management and Thoracic Innovation/Cardiac Surgery), Poitiers University Hospital, Poitiers, France.
Lisa GoudmanSTIMULUS Research Group (reSearch and TeachIng neuroModULation Uz bruSsel), Vrije Universiteit Brussel, Brussels, Belgium.
Vrije Universiteit Brussel · BEUniversité de Poitiers · FRInstitut Pprime · FRResearch Foundation - Flanders · BEUniversitair Ziekenhuis Brussel · BEUniversity of Liverpool · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Coronavirus disease 2019 (COVID-19) pandemic exerted a tremendous pressure on the healthcare system, people's social life, mental health and financial status with profound implications for the general population. The exact impact of the pandemic on the overall physical, mental and social wellbeing of COVID-19 infection survivors on the long term has not yet been explored in a thorough way. Based on the reporting of persistent pain, fatigue and dyspnea symptoms by these survivors, it is our hypothesis that their quality of life will be extremely impacted, as is observed in patients with chronic pain. Therefore, the first aim of this study was to perform an in-depth evaluation of the quality of life of post-COVID-19 infected persons. The second aim was to compare the quality of life of these persons with a normative population and with patients with chronic pain. Health-related quality of life, as a measure for a person's overall physical, mental, and social wellbeing, was measured with the 3-level EQ5D in 547 post-COVID-19 infected persons. These data were compared to reference data from normal population records for Belgium and to data from patients with chronic pain after spinal surgery with two-way analyses of variance. In total, 89.58% of the post-COVID-19 infected persons reported pain/discomfort and 82.45% indicated limitations when performing usual activities, when evaluated 287 days (SD: 150) after the infection. Self-care was preserved in most post-COVID-19 persons, whereby only 13.16% indicated problems. The mean EQ5D-3L index score was 0.57 (SD: 0.23) and EQ5D VAS mean score was 56.6 (SD: 18.2). The mean index score for the normative population was significantly higher than for COVID-19 infected persons [mean difference of 0.31 (95% from 0.29 to 0.33), Clinical trial registration: https://www.clinicaltrials.gov/, identifier: NCT04912778.

Indexed as

Chronic PainCOVID-19HumansPandemicsPost-Acute COVID-19 SyndromeQuality of Lifeburden of diseasechronic painCOVID-19EQ5D-3Lhealth-related quality of life

Identifiers

PMID36339175
PMCPMC9632164
OpenAlexW4306874554

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.