Evidence map›Paper›PMID 36339063›Full record

ArticleRadiology. Cardiothoracic imaging2022

Distinguishing Type 1 from Type 2 Myocardial Infarction by Using CT Coronary Angiography.

Mohammed N Meah, Anda Bularga, Evangelos Tzolos, Andrew R Chapman, Marwa Daghem, John D Hung, Justin Chiong, Caelan Taggart, Ryan Wereski, Alasdair Gray and 10 more

2 registry-linked trialsOpen access · greenAbstract read
In one paragraph

Article in Radiology. Cardiothoracic imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02284191 nacompletednot on this map

The Role of Early CT Coronary Angiography in the Evaluation, Intervention and Outcome of Patients Presenting to the Emergency Department With Suspected or Confirmed Acute Coronary Syndrome.

TypeinterventionalSponsorUniversity of EdinburghRan2015 to 2020Enrolled1,749ConditionsAcute Coronary SyndromeArmsCT Coronary Angiogram
NCT03338504 completednot on this map

Determining the Mechanism of Myocardial Injury and Role of Coronary Disease in Type 2 Myocardial Infarction

TypeobservationalSponsorUniversity of EdinburghRan2017 to 2021Enrolled100ConditionsMyocardial Infarction, Acute, Myocardial Ischemia, Myocardial InjuryArmsInvasive coronary angiography, CT coronary angiography, Cardiac MRI
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Radiology. Cardiothoracic imaging · 2023
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 4 institutions in 2 countries.

Mohammed N MeahBritish Heart Foundation Centre of Cardiovascular Science, University of Edinburgh, Edinburgh, Scotland (M.N.M., A.B., E.T., A.R.C., M.D., J.D.H., J.C., C.T., R.W., A.G., M.R.D., N.L.M., D.E.N., M.C.W.); Usher Institute, University of Edinburgh, Edinburgh, Scotland (A.G., N.L.M.); University Hospital Plymouth, Plymouth, England (C.R.); Faculty of Medicine, University of Southampton, Southampton, England (N.C.); University Hospital Southampton, Southampton, England (N.C.); Department of Cardiology, Milton Keynes University Hospital, School of Sciences and Medicine, University of Buckingham, Buckingham, England (A.K.); Torbay and South Devon NHS Foundation Trust, Torquay, England (D.F.); Departments of Medicine and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, Calif (P.J.S., D.D.); and Edinburgh Imaging, Queen's Medical Research Institute University of Edinburgh, Edinburgh, Scotland (D.E.N., M.C.W.).ORCID 0000-0002-0806-9972
Anda BulargaBritish Heart Foundation Centre of Cardiovascular Science, University of Edinburgh, Edinburgh, Scotland (M.N.M., A.B., E.T., A.R.C., M.D., J.D.H., J.C., C.T., R.W., A.G., M.R.D., N.L.M., D.E.N., M.C.W.); Usher Institute, University of Edinburgh, Edinburgh, Scotland (A.G., N.L.M.); University Hospital Plymouth, Plymouth, England (C.R.); Faculty of Medicine, University of Southampton, Southampton, England (N.C.); University Hospital Southampton, Southampton, England (N.C.); Department of Cardiology, Milton Keynes University Hospital, School of Sciences and Medicine, University of Buckingham, Buckingham, England (A.K.); Torbay and South Devon NHS Foundation Trust, Torquay, England (D.F.); Departments of Medicine and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, Calif (P.J.S., D.D.); and Edinburgh Imaging, Queen's Medical Research Institute University of Edinburgh, Edinburgh, Scotland (D.E.N., M.C.W.).ORCID 0000-0002-5530-527X
Evangelos TzolosBritish Heart Foundation Centre of Cardiovascular Science, University of Edinburgh, Edinburgh, Scotland (M.N.M., A.B., E.T., A.R.C., M.D., J.D.H., J.C., C.T., R.W., A.G., M.R.D., N.L.M., D.E.N., M.C.W.); Usher Institute, University of Edinburgh, Edinburgh, Scotland (A.G., N.L.M.); University Hospital Plymouth, Plymouth, England (C.R.); Faculty of Medicine, University of Southampton, Southampton, England (N.C.); University Hospital Southampton, Southampton, England (N.C.); Department of Cardiology, Milton Keynes University Hospital, School of Sciences and Medicine, University of Buckingham, Buckingham, England (A.K.); Torbay and South Devon NHS Foundation Trust, Torquay, England (D.F.); Departments of Medicine and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, Calif (P.J.S., D.D.); and Edinburgh Imaging, Queen's Medical Research Institute University of Edinburgh, Edinburgh, Scotland (D.E.N., M.C.W.).ORCID 0000-0003-0038-043X
Andrew R ChapmanBritish Heart Foundation Centre of Cardiovascular Science, University of Edinburgh, Edinburgh, Scotland (M.N.M., A.B., E.T., A.R.C., M.D., J.D.H., J.C., C.T., R.W., A.G., M.R.D., N.L.M., D.E.N., M.C.W.); Usher Institute, University of Edinburgh, Edinburgh, Scotland (A.G., N.L.M.); University Hospital Plymouth, Plymouth, England (C.R.); Faculty of Medicine, University of Southampton, Southampton, England (N.C.); University Hospital Southampton, Southampton, England (N.C.); Department of Cardiology, Milton Keynes University Hospital, School of Sciences and Medicine, University of Buckingham, Buckingham, England (A.K.); Torbay and South Devon NHS Foundation Trust, Torquay, England (D.F.); Departments of Medicine and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, Calif (P.J.S., D.D.); and Edinburgh Imaging, Queen's Medical Research Institute University of Edinburgh, Edinburgh, Scotland (D.E.N., M.C.W.).
Marwa DaghemBritish Heart Foundation Centre of Cardiovascular Science, University of Edinburgh, Edinburgh, Scotland (M.N.M., A.B., E.T., A.R.C., M.D., J.D.H., J.C., C.T., R.W., A.G., M.R.D., N.L.M., D.E.N., M.C.W.); Usher Institute, University of Edinburgh, Edinburgh, Scotland (A.G., N.L.M.); University Hospital Plymouth, Plymouth, England (C.R.); Faculty of Medicine, University of Southampton, Southampton, England (N.C.); University Hospital Southampton, Southampton, England (N.C.); Department of Cardiology, Milton Keynes University Hospital, School of Sciences and Medicine, University of Buckingham, Buckingham, England (A.K.); Torbay and South Devon NHS Foundation Trust, Torquay, England (D.F.); Departments of Medicine and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, Calif (P.J.S., D.D.); and Edinburgh Imaging, Queen's Medical Research Institute University of Edinburgh, Edinburgh, Scotland (D.E.N., M.C.W.).
John D HungBritish Heart Foundation Centre of Cardiovascular Science, University of Edinburgh, Edinburgh, Scotland (M.N.M., A.B., E.T., A.R.C., M.D., J.D.H., J.C., C.T., R.W., A.G., M.R.D., N.L.M., D.E.N., M.C.W.); Usher Institute, University of Edinburgh, Edinburgh, Scotland (A.G., N.L.M.); University Hospital Plymouth, Plymouth, England (C.R.); Faculty of Medicine, University of Southampton, Southampton, England (N.C.); University Hospital Southampton, Southampton, England (N.C.); Department of Cardiology, Milton Keynes University Hospital, School of Sciences and Medicine, University of Buckingham, Buckingham, England (A.K.); Torbay and South Devon NHS Foundation Trust, Torquay, England (D.F.); Departments of Medicine and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, Calif (P.J.S., D.D.); and Edinburgh Imaging, Queen's Medical Research Institute University of Edinburgh, Edinburgh, Scotland (D.E.N., M.C.W.).ORCID 0000-0002-2269-2947
Justin ChiongBritish Heart Foundation Centre of Cardiovascular Science, University of Edinburgh, Edinburgh, Scotland (M.N.M., A.B., E.T., A.R.C., M.D., J.D.H., J.C., C.T., R.W., A.G., M.R.D., N.L.M., D.E.N., M.C.W.); Usher Institute, University of Edinburgh, Edinburgh, Scotland (A.G., N.L.M.); University Hospital Plymouth, Plymouth, England (C.R.); Faculty of Medicine, University of Southampton, Southampton, England (N.C.); University Hospital Southampton, Southampton, England (N.C.); Department of Cardiology, Milton Keynes University Hospital, School of Sciences and Medicine, University of Buckingham, Buckingham, England (A.K.); Torbay and South Devon NHS Foundation Trust, Torquay, England (D.F.); Departments of Medicine and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, Calif (P.J.S., D.D.); and Edinburgh Imaging, Queen's Medical Research Institute University of Edinburgh, Edinburgh, Scotland (D.E.N., M.C.W.).ORCID 0000-0003-3795-5639
Caelan TaggartBritish Heart Foundation Centre of Cardiovascular Science, University of Edinburgh, Edinburgh, Scotland (M.N.M., A.B., E.T., A.R.C., M.D., J.D.H., J.C., C.T., R.W., A.G., M.R.D., N.L.M., D.E.N., M.C.W.); Usher Institute, University of Edinburgh, Edinburgh, Scotland (A.G., N.L.M.); University Hospital Plymouth, Plymouth, England (C.R.); Faculty of Medicine, University of Southampton, Southampton, England (N.C.); University Hospital Southampton, Southampton, England (N.C.); Department of Cardiology, Milton Keynes University Hospital, School of Sciences and Medicine, University of Buckingham, Buckingham, England (A.K.); Torbay and South Devon NHS Foundation Trust, Torquay, England (D.F.); Departments of Medicine and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, Calif (P.J.S., D.D.); and Edinburgh Imaging, Queen's Medical Research Institute University of Edinburgh, Edinburgh, Scotland (D.E.N., M.C.W.).
Ryan WereskiBritish Heart Foundation Centre of Cardiovascular Science, University of Edinburgh, Edinburgh, Scotland (M.N.M., A.B., E.T., A.R.C., M.D., J.D.H., J.C., C.T., R.W., A.G., M.R.D., N.L.M., D.E.N., M.C.W.); Usher Institute, University of Edinburgh, Edinburgh, Scotland (A.G., N.L.M.); University Hospital Plymouth, Plymouth, England (C.R.); Faculty of Medicine, University of Southampton, Southampton, England (N.C.); University Hospital Southampton, Southampton, England (N.C.); Department of Cardiology, Milton Keynes University Hospital, School of Sciences and Medicine, University of Buckingham, Buckingham, England (A.K.); Torbay and South Devon NHS Foundation Trust, Torquay, England (D.F.); Departments of Medicine and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, Calif (P.J.S., D.D.); and Edinburgh Imaging, Queen's Medical Research Institute University of Edinburgh, Edinburgh, Scotland (D.E.N., M.C.W.).ORCID 0000-0001-6485-453X
Alasdair GrayBritish Heart Foundation Centre of Cardiovascular Science, University of Edinburgh, Edinburgh, Scotland (M.N.M., A.B., E.T., A.R.C., M.D., J.D.H., J.C., C.T., R.W., A.G., M.R.D., N.L.M., D.E.N., M.C.W.); Usher Institute, University of Edinburgh, Edinburgh, Scotland (A.G., N.L.M.); University Hospital Plymouth, Plymouth, England (C.R.); Faculty of Medicine, University of Southampton, Southampton, England (N.C.); University Hospital Southampton, Southampton, England (N.C.); Department of Cardiology, Milton Keynes University Hospital, School of Sciences and Medicine, University of Buckingham, Buckingham, England (A.K.); Torbay and South Devon NHS Foundation Trust, Torquay, England (D.F.); Departments of Medicine and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, Calif (P.J.S., D.D.); and Edinburgh Imaging, Queen's Medical Research Institute University of Edinburgh, Edinburgh, Scotland (D.E.N., M.C.W.).
Marc R DweckBritish Heart Foundation Centre of Cardiovascular Science, University of Edinburgh, Edinburgh, Scotland (M.N.M., A.B., E.T., A.R.C., M.D., J.D.H., J.C., C.T., R.W., A.G., M.R.D., N.L.M., D.E.N., M.C.W.); Usher Institute, University of Edinburgh, Edinburgh, Scotland (A.G., N.L.M.); University Hospital Plymouth, Plymouth, England (C.R.); Faculty of Medicine, University of Southampton, Southampton, England (N.C.); University Hospital Southampton, Southampton, England (N.C.); Department of Cardiology, Milton Keynes University Hospital, School of Sciences and Medicine, University of Buckingham, Buckingham, England (A.K.); Torbay and South Devon NHS Foundation Trust, Torquay, England (D.F.); Departments of Medicine and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, Calif (P.J.S., D.D.); and Edinburgh Imaging, Queen's Medical Research Institute University of Edinburgh, Edinburgh, Scotland (D.E.N., M.C.W.).
Carl RoobottomBritish Heart Foundation Centre of Cardiovascular Science, University of Edinburgh, Edinburgh, Scotland (M.N.M., A.B., E.T., A.R.C., M.D., J.D.H., J.C., C.T., R.W., A.G., M.R.D., N.L.M., D.E.N., M.C.W.); Usher Institute, University of Edinburgh, Edinburgh, Scotland (A.G., N.L.M.); University Hospital Plymouth, Plymouth, England (C.R.); Faculty of Medicine, University of Southampton, Southampton, England (N.C.); University Hospital Southampton, Southampton, England (N.C.); Department of Cardiology, Milton Keynes University Hospital, School of Sciences and Medicine, University of Buckingham, Buckingham, England (A.K.); Torbay and South Devon NHS Foundation Trust, Torquay, England (D.F.); Departments of Medicine and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, Calif (P.J.S., D.D.); and Edinburgh Imaging, Queen's Medical Research Institute University of Edinburgh, Edinburgh, Scotland (D.E.N., M.C.W.).ORCID 0000-0001-5066-7645
Nick CurzenBritish Heart Foundation Centre of Cardiovascular Science, University of Edinburgh, Edinburgh, Scotland (M.N.M., A.B., E.T., A.R.C., M.D., J.D.H., J.C., C.T., R.W., A.G., M.R.D., N.L.M., D.E.N., M.C.W.); Usher Institute, University of Edinburgh, Edinburgh, Scotland (A.G., N.L.M.); University Hospital Plymouth, Plymouth, England (C.R.); Faculty of Medicine, University of Southampton, Southampton, England (N.C.); University Hospital Southampton, Southampton, England (N.C.); Department of Cardiology, Milton Keynes University Hospital, School of Sciences and Medicine, University of Buckingham, Buckingham, England (A.K.); Torbay and South Devon NHS Foundation Trust, Torquay, England (D.F.); Departments of Medicine and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, Calif (P.J.S., D.D.); and Edinburgh Imaging, Queen's Medical Research Institute University of Edinburgh, Edinburgh, Scotland (D.E.N., M.C.W.).ORCID 0000-0001-9651-7829
Attila KardosBritish Heart Foundation Centre of Cardiovascular Science, University of Edinburgh, Edinburgh, Scotland (M.N.M., A.B., E.T., A.R.C., M.D., J.D.H., J.C., C.T., R.W., A.G., M.R.D., N.L.M., D.E.N., M.C.W.); Usher Institute, University of Edinburgh, Edinburgh, Scotland (A.G., N.L.M.); University Hospital Plymouth, Plymouth, England (C.R.); Faculty of Medicine, University of Southampton, Southampton, England (N.C.); University Hospital Southampton, Southampton, England (N.C.); Department of Cardiology, Milton Keynes University Hospital, School of Sciences and Medicine, University of Buckingham, Buckingham, England (A.K.); Torbay and South Devon NHS Foundation Trust, Torquay, England (D.F.); Departments of Medicine and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, Calif (P.J.S., D.D.); and Edinburgh Imaging, Queen's Medical Research Institute University of Edinburgh, Edinburgh, Scotland (D.E.N., M.C.W.).ORCID 0000-0002-0231-7605
Dirk FelmedenBritish Heart Foundation Centre of Cardiovascular Science, University of Edinburgh, Edinburgh, Scotland (M.N.M., A.B., E.T., A.R.C., M.D., J.D.H., J.C., C.T., R.W., A.G., M.R.D., N.L.M., D.E.N., M.C.W.); Usher Institute, University of Edinburgh, Edinburgh, Scotland (A.G., N.L.M.); University Hospital Plymouth, Plymouth, England (C.R.); Faculty of Medicine, University of Southampton, Southampton, England (N.C.); University Hospital Southampton, Southampton, England (N.C.); Department of Cardiology, Milton Keynes University Hospital, School of Sciences and Medicine, University of Buckingham, Buckingham, England (A.K.); Torbay and South Devon NHS Foundation Trust, Torquay, England (D.F.); Departments of Medicine and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, Calif (P.J.S., D.D.); and Edinburgh Imaging, Queen's Medical Research Institute University of Edinburgh, Edinburgh, Scotland (D.E.N., M.C.W.).
Nicholas L MillsBritish Heart Foundation Centre of Cardiovascular Science, University of Edinburgh, Edinburgh, Scotland (M.N.M., A.B., E.T., A.R.C., M.D., J.D.H., J.C., C.T., R.W., A.G., M.R.D., N.L.M., D.E.N., M.C.W.); Usher Institute, University of Edinburgh, Edinburgh, Scotland (A.G., N.L.M.); University Hospital Plymouth, Plymouth, England (C.R.); Faculty of Medicine, University of Southampton, Southampton, England (N.C.); University Hospital Southampton, Southampton, England (N.C.); Department of Cardiology, Milton Keynes University Hospital, School of Sciences and Medicine, University of Buckingham, Buckingham, England (A.K.); Torbay and South Devon NHS Foundation Trust, Torquay, England (D.F.); Departments of Medicine and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, Calif (P.J.S., D.D.); and Edinburgh Imaging, Queen's Medical Research Institute University of Edinburgh, Edinburgh, Scotland (D.E.N., M.C.W.).ORCID 0000-0003-0533-7991
Piotr J SlomkaBritish Heart Foundation Centre of Cardiovascular Science, University of Edinburgh, Edinburgh, Scotland (M.N.M., A.B., E.T., A.R.C., M.D., J.D.H., J.C., C.T., R.W., A.G., M.R.D., N.L.M., D.E.N., M.C.W.); Usher Institute, University of Edinburgh, Edinburgh, Scotland (A.G., N.L.M.); University Hospital Plymouth, Plymouth, England (C.R.); Faculty of Medicine, University of Southampton, Southampton, England (N.C.); University Hospital Southampton, Southampton, England (N.C.); Department of Cardiology, Milton Keynes University Hospital, School of Sciences and Medicine, University of Buckingham, Buckingham, England (A.K.); Torbay and South Devon NHS Foundation Trust, Torquay, England (D.F.); Departments of Medicine and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, Calif (P.J.S., D.D.); and Edinburgh Imaging, Queen's Medical Research Institute University of Edinburgh, Edinburgh, Scotland (D.E.N., M.C.W.).ORCID 0000-0002-6110-938X
David E NewbyBritish Heart Foundation Centre of Cardiovascular Science, University of Edinburgh, Edinburgh, Scotland (M.N.M., A.B., E.T., A.R.C., M.D., J.D.H., J.C., C.T., R.W., A.G., M.R.D., N.L.M., D.E.N., M.C.W.); Usher Institute, University of Edinburgh, Edinburgh, Scotland (A.G., N.L.M.); University Hospital Plymouth, Plymouth, England (C.R.); Faculty of Medicine, University of Southampton, Southampton, England (N.C.); University Hospital Southampton, Southampton, England (N.C.); Department of Cardiology, Milton Keynes University Hospital, School of Sciences and Medicine, University of Buckingham, Buckingham, England (A.K.); Torbay and South Devon NHS Foundation Trust, Torquay, England (D.F.); Departments of Medicine and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, Calif (P.J.S., D.D.); and Edinburgh Imaging, Queen's Medical Research Institute University of Edinburgh, Edinburgh, Scotland (D.E.N., M.C.W.).ORCID 0000-0001-7971-4628
Damini Dey *British Heart Foundation Centre of Cardiovascular Science, University of Edinburgh, Edinburgh, Scotland (M.N.M., A.B., E.T., A.R.C., M.D., J.D.H., J.C., C.T., R.W., A.G., M.R.D., N.L.M., D.E.N., M.C.W.); Usher Institute, University of Edinburgh, Edinburgh, Scotland (A.G., N.L.M.); University Hospital Plymouth, Plymouth, England (C.R.); Faculty of Medicine, University of Southampton, Southampton, England (N.C.); University Hospital Southampton, Southampton, England (N.C.); Department of Cardiology, Milton Keynes University Hospital, School of Sciences and Medicine, University of Buckingham, Buckingham, England (A.K.); Torbay and South Devon NHS Foundation Trust, Torquay, England (D.F.); Departments of Medicine and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, Calif (P.J.S., D.D.); and Edinburgh Imaging, Queen's Medical Research Institute University of Edinburgh, Edinburgh, Scotland (D.E.N., M.C.W.).ORCID 0000-0003-2236-6970
Michelle C Williams *British Heart Foundation Centre of Cardiovascular Science, University of Edinburgh, Edinburgh, Scotland (M.N.M., A.B., E.T., A.R.C., M.D., J.D.H., J.C., C.T., R.W., A.G., M.R.D., N.L.M., D.E.N., M.C.W.); Usher Institute, University of Edinburgh, Edinburgh, Scotland (A.G., N.L.M.); University Hospital Plymouth, Plymouth, England (C.R.); Faculty of Medicine, University of Southampton, Southampton, England (N.C.); University Hospital Southampton, Southampton, England (N.C.); Department of Cardiology, Milton Keynes University Hospital, School of Sciences and Medicine, University of Buckingham, Buckingham, England (A.K.); Torbay and South Devon NHS Foundation Trust, Torquay, England (D.F.); Departments of Medicine and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, Calif (P.J.S., D.D.); and Edinburgh Imaging, Queen's Medical Research Institute University of Edinburgh, Edinburgh, Scotland (D.E.N., M.C.W.).ORCID 0000-0003-3556-2428
British Heart Foundation · GBCedars-Sinai Medical Center · USMilton Keynes Hospital · GBUniversity Hospital Southampton NHS Foundation Trust · GB

Funding

Integrated prediction of cardiovascular events by automated coronary plaque and pericoronary adipose tissue quantification from CT AngiographyR01HL148787 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI DEY, DAMINI · 2020 to 2023
$3.0M
Effect of Intensive Medical Treatment on Quantified Coronary Artery Plaque Components with Serial Coronary CTA in Women with Non-Obstructive CADR01HL151266 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI DEY, DAMINI, TAMARAPPOO, BALAJI K. · 2020 to 2023
$1.6M
British Heart Foundation CH/09/002British Heart Foundation CH/09/002/26360British Heart Foundation CH/F/21/90010British Heart Foundation FS/16/75/32533British Heart Foundation FS/CRTF/20/24086British Heart Foundation FS/CRTF/21/24273British Heart Foundation FS/ICRF/20/26002British Heart Foundation RE/18/5/34216British Heart Foundation RG/16/10/32375British Heart Foundation RG/20/10/34966Medical Research Council G0701127Medical Research Council MR/V007017/1Medical Research Council MR/V007254/1NHLBI NIH HHS R01 HL148787NHLBI NIH HHS R01 HL151266
6 · The paper itself

Abstract

Purpose: To determine whether quantitative plaque characterization by using CT coronary angiography (CTCA) can discriminate between type 1 and type 2 myocardial infarction. Materials and Methods: This was a secondary analysis of two prospective studies (ClinicalTrials.gov registration nos. NCT03338504 [2014-2019] and NCT02284191 [2018-2020]) that performed blinded quantitative plaque analysis on findings from CTCA in participants with type 1 myocardial infarction, type 2 myocardial infarction, and chest pain without myocardial infarction. Logistic regression analyses were performed to identify predictors of type 1 myocardial infarction. Results: Overall, 155 participants (mean age, 64 years ± 12 [SD]; 114 men) and 36 participants (mean age, 67 years ± 12; 19 men) had type 1 and type 2 myocardial infarction, respectively, and 136 participants (62 years ± 12; 78 men) had chest pain without myocardial infarction. Participants with type 1 myocardial infarction had greater total (median, 44% [IQR: 35%-50%] vs 35% [IQR: 29%-46%]), noncalcified (39% [IQR: 31%-46%] vs 34% [IQR: 29%-40%]), and low-attenuation (4.15% [IQR: 1.88%-5.79%] vs 1.64% [IQR: 0.89%-2.28%]) plaque burdens ( Conclusion: Higher low-attenuation coronary plaque burden in patients with type 1 myocardial infarction may help distinguish these patients from those with type 2 myocardial infarction.

Indexed as

CT AngiographyIschemia/InfarctionQuantitative CT

Identifiers

PMID36339063
PMCPMC9627233
OpenAlexW4307641249

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.