Evidence map›Paper›PMID 36339060›Full record

ArticleRadiology. Cardiothoracic imaging2022

Correlation between Cardiac MRI and Voltage Mapping in Evaluating Atrial Fibrosis: A Systematic Review.

Geertruida P Bijvoet, Hedwig M J M Nies, Robert J Holtackers, Dominik Linz, Bouke P Adriaans, Robin Nijveldt, Joachim E Wildberger, Kevin Vernooy, Sevasti-Maria Chaldoupi, Casper Mihl

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In one paragraph

Article in Radiology. Cardiothoracic imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Prevalence and multiple predictors of left atrial low voltage in paroxysmal and non-paroxysmal atrial fibrillation patients undergoing ablation: a systematic review and meta-analysis.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Pooled it
  2. Observational
  3. Article
  4. Review
  5. Relationships between three-dimensional fibrosis distribution, atrial adiposity, and voltage abnormalities associated with persistent atrial fibrillation.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
    Article
  6. Article
  7. Article
  8. Assessment of Left Atrial Fibrosis With Cardiac MRI.Journal of magnetic resonance imaging : JMRI · 2025
    Article
  9. Review
  10. Article
  11. Non-invasive prediction of atrial cardiomyopathy characterized by multipolar high-density contact mapping.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Comparison of voltages between atria: differences in sinus rhythm and atrial fibrillation.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2024
    Article
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Geertruida P BijvoetCardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, the Netherlands (G.P.B., H.M.J.M.N., R.J.H., D.L., B.P.A., J.E.W., K.V., C.M.); Department of Cardiology (G.P.B., D.L., B.P.A., K.V., S.M.C.) and Department of Radiology and Nuclear Medicine (H.M.J.M.N., R.J.H., B.P.A., J.E.W., C.M.), Maastricht University Medical Centre, P. Debyelaan 25, PO Box 5800, 6229 HX Maastricht, the Netherlands; and Department of Cardiology, Radboud University Medical Centre, Nijmegen, the Netherlands (G.P.B., D.L., R.N., K.V.).ORCID https://orcid.org/0000-0002-3475-0155
Hedwig M J M NiesCardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, the Netherlands (G.P.B., H.M.J.M.N., R.J.H., D.L., B.P.A., J.E.W., K.V., C.M.); Department of Cardiology (G.P.B., D.L., B.P.A., K.V., S.M.C.) and Department of Radiology and Nuclear Medicine (H.M.J.M.N., R.J.H., B.P.A., J.E.W., C.M.), Maastricht University Medical Centre, P. Debyelaan 25, PO Box 5800, 6229 HX Maastricht, the Netherlands; and Department of Cardiology, Radboud University Medical Centre, Nijmegen, the Netherlands (G.P.B., D.L., R.N., K.V.).ORCID 0000-0002-1309-9965
Robert J HoltackersCardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, the Netherlands (G.P.B., H.M.J.M.N., R.J.H., D.L., B.P.A., J.E.W., K.V., C.M.); Department of Cardiology (G.P.B., D.L., B.P.A., K.V., S.M.C.) and Department of Radiology and Nuclear Medicine (H.M.J.M.N., R.J.H., B.P.A., J.E.W., C.M.), Maastricht University Medical Centre, P. Debyelaan 25, PO Box 5800, 6229 HX Maastricht, the Netherlands; and Department of Cardiology, Radboud University Medical Centre, Nijmegen, the Netherlands (G.P.B., D.L., R.N., K.V.).ORCID 0000-0003-1809-313X
Dominik LinzCardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, the Netherlands (G.P.B., H.M.J.M.N., R.J.H., D.L., B.P.A., J.E.W., K.V., C.M.); Department of Cardiology (G.P.B., D.L., B.P.A., K.V., S.M.C.) and Department of Radiology and Nuclear Medicine (H.M.J.M.N., R.J.H., B.P.A., J.E.W., C.M.), Maastricht University Medical Centre, P. Debyelaan 25, PO Box 5800, 6229 HX Maastricht, the Netherlands; and Department of Cardiology, Radboud University Medical Centre, Nijmegen, the Netherlands (G.P.B., D.L., R.N., K.V.).ORCID 0000-0003-4893-0824
Bouke P AdriaansCardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, the Netherlands (G.P.B., H.M.J.M.N., R.J.H., D.L., B.P.A., J.E.W., K.V., C.M.); Department of Cardiology (G.P.B., D.L., B.P.A., K.V., S.M.C.) and Department of Radiology and Nuclear Medicine (H.M.J.M.N., R.J.H., B.P.A., J.E.W., C.M.), Maastricht University Medical Centre, P. Debyelaan 25, PO Box 5800, 6229 HX Maastricht, the Netherlands; and Department of Cardiology, Radboud University Medical Centre, Nijmegen, the Netherlands (G.P.B., D.L., R.N., K.V.).ORCID 0000-0002-4409-6206
Robin NijveldtCardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, the Netherlands (G.P.B., H.M.J.M.N., R.J.H., D.L., B.P.A., J.E.W., K.V., C.M.); Department of Cardiology (G.P.B., D.L., B.P.A., K.V., S.M.C.) and Department of Radiology and Nuclear Medicine (H.M.J.M.N., R.J.H., B.P.A., J.E.W., C.M.), Maastricht University Medical Centre, P. Debyelaan 25, PO Box 5800, 6229 HX Maastricht, the Netherlands; and Department of Cardiology, Radboud University Medical Centre, Nijmegen, the Netherlands (G.P.B., D.L., R.N., K.V.).
Joachim E WildbergerCardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, the Netherlands (G.P.B., H.M.J.M.N., R.J.H., D.L., B.P.A., J.E.W., K.V., C.M.); Department of Cardiology (G.P.B., D.L., B.P.A., K.V., S.M.C.) and Department of Radiology and Nuclear Medicine (H.M.J.M.N., R.J.H., B.P.A., J.E.W., C.M.), Maastricht University Medical Centre, P. Debyelaan 25, PO Box 5800, 6229 HX Maastricht, the Netherlands; and Department of Cardiology, Radboud University Medical Centre, Nijmegen, the Netherlands (G.P.B., D.L., R.N., K.V.).
Kevin VernooyCardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, the Netherlands (G.P.B., H.M.J.M.N., R.J.H., D.L., B.P.A., J.E.W., K.V., C.M.); Department of Cardiology (G.P.B., D.L., B.P.A., K.V., S.M.C.) and Department of Radiology and Nuclear Medicine (H.M.J.M.N., R.J.H., B.P.A., J.E.W., C.M.), Maastricht University Medical Centre, P. Debyelaan 25, PO Box 5800, 6229 HX Maastricht, the Netherlands; and Department of Cardiology, Radboud University Medical Centre, Nijmegen, the Netherlands (G.P.B., D.L., R.N., K.V.).ORCID 0000-0002-8818-5964
Sevasti-Maria Chaldoupi *Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, the Netherlands (G.P.B., H.M.J.M.N., R.J.H., D.L., B.P.A., J.E.W., K.V., C.M.); Department of Cardiology (G.P.B., D.L., B.P.A., K.V., S.M.C.) and Department of Radiology and Nuclear Medicine (H.M.J.M.N., R.J.H., B.P.A., J.E.W., C.M.), Maastricht University Medical Centre, P. Debyelaan 25, PO Box 5800, 6229 HX Maastricht, the Netherlands; and Department of Cardiology, Radboud University Medical Centre, Nijmegen, the Netherlands (G.P.B., D.L., R.N., K.V.).
Casper Mihl *Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, the Netherlands (G.P.B., H.M.J.M.N., R.J.H., D.L., B.P.A., J.E.W., K.V., C.M.); Department of Cardiology (G.P.B., D.L., B.P.A., K.V., S.M.C.) and Department of Radiology and Nuclear Medicine (H.M.J.M.N., R.J.H., B.P.A., J.E.W., C.M.), Maastricht University Medical Centre, P. Debyelaan 25, PO Box 5800, 6229 HX Maastricht, the Netherlands; and Department of Cardiology, Radboud University Medical Centre, Nijmegen, the Netherlands (G.P.B., D.L., R.N., K.V.).ORCID 0000-0003-1348-6970

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To provide an overview of existing literature on the association between late gadolinium enhancement (LGE) cardiac MRI and low voltage areas (LVA) obtained with electroanatomic mapping (EAM) or histopathology when assessing atrial fibrosis. Materials and Methods: A systematic literature search was conducted in the PubMed, Embase, and Cochrane Library databases to identify all studies published until June 7, 2022, comparing LGE cardiac MRI to LVA EAM and/or histopathology for evaluation of atrial fibrosis. The study protocol was registered at PROSPERO (registration no. CRD42022338243). Two reviewers independently evaluated the studies for inclusion. Risk of bias and applicability for each included study were assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2) criteria. Data regarding demographics, electrophysiology, LGE cardiac MRI, and study outcomes were extracted. Results: The search yielded 1048 total results, of which 22 studies were included. Nineteen of the 22 included studies reported a significant correlation between high signal intensity at LGE cardiac MRI and LVA EAM or histopathology. However, there was great heterogeneity between included studies regarding study design, patient samples, cardiac MRI performance and postprocessing, and EAM performance. Conclusion: Current literature suggests a correlation between LGE cardiac MRI and LVA EAM or histopathology when evaluating atrial fibrosis but high heterogeneity between studies, demonstrating the need for uniform choices regarding cardiac MRI and EAM acquisition in future studies.

Indexed as

CardiacLeft AtriumMR Imaging

Identifiers

PMID36339060
PMCPMC9627236

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.