Evidence map›Paper›PMID 36338755›Full record

ReviewFrontiers in oncology2022

Tumor microenvironment in non-melanoma skin cancer resistance to photodynamic therapy.

Paulina A Cerro, Marta Mascaraque, María Gallego-Rentero, Manuel Almenara-Blasco, Jimena Nicolás-Morala, Juan Luis Santiago, Salvador González, Tamara Gracia-Cazaña, Ángeles Juarranz, Yolanda Gilaberte

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Paulina A CerroDepartment of Dermatology, Miguel Servet University Hospital, Instituto Investigación Sanitaria (IIS), Zaragoza, Aragón, Spain.
Marta MascaraqueDepartment of Biology, Universidad Autónoma de Madrid, Madrid, Spain.
María Gallego-RenteroDepartment of Biology, Universidad Autónoma de Madrid, Madrid, Spain.
Manuel Almenara-BlascoDepartment of Dermatology, Miguel Servet University Hospital, Instituto Investigación Sanitaria (IIS), Zaragoza, Aragón, Spain.
Jimena Nicolás-MoralaDepartment of Biology, Universidad Autónoma de Madrid, Madrid, Spain.
Juan Luis SantiagoServicio de Dermatología, Hospital General de Ciudad Real, Ciudad Real, Spain.
Salvador GonzálezDepartment of Medicine and Medical Specialties, Universidad de Alcalá, Madrid, Spain.
Tamara Gracia-CazañaDepartment of Dermatology, Miguel Servet University Hospital, Instituto Investigación Sanitaria (IIS), Zaragoza, Aragón, Spain.
Ángeles JuarranzDepartment of Biology, Universidad Autónoma de Madrid, Madrid, Spain.
Yolanda GilaberteDepartment of Dermatology, Miguel Servet University Hospital, Instituto Investigación Sanitaria (IIS), Zaragoza, Aragón, Spain.
Instituto de Investigación Sanitaria Aragón · ESInstituto Ramón y Cajal de Investigación Sanitaria · ESHospital General Universitario de Ciudad Real · ESUniversidad Autónoma de Madrid · ESUniversidad de Alcalá · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-melanoma skin cancer has recently seen an increase in prevalence, and it is estimated that this grow will continue in the coming years. In this sense, the importance of therapy effectiveness has increased, especially photodynamic therapy. Photodynamic therapy has attracted much attention as a minimally invasive, selective and repeatable approach for skin cancer treatment and prevention. Although its high efficiency, this strategy has also faced problems related to tumor resistance, where the tumor microenvironment has gained a well-deserved role in recent years. Tumor microenvironment denotes a wide variety of elements, such as cancer-associated fibroblasts, immune cells, endothelial cells or the extracellular matrix, where their interaction and the secretion of a wide diversity of cytokines. Therefore, the need of

Indexed as

cancer-asssociated fiboroblastsimmune cellsmast cellnon-melanoma skin cancerphotodynamic therapyresistancetumor microenvironment

Identifiers

PMID36338755
PMCPMC9634550
OpenAlexW4307166413

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.