Evidence map›Paper›PMID 36338590›Full record

ArticleAnnals of gastroenterological surgery2022

Current clinical practice for familial adenomatous polyposis in Japan: A nationwide multicenter study.

Takaaki Matsubara, Naohito Beppu, Masataka Ikeda, Hideyuki Ishida, Yoji Takeuchi, Toshiya Nagasaki, Akinari Takao, Kazuhito Sasaki, Kiwamu Akagi, Tomoya Sudo and 4 more

Open access · goldAbstract read
In one paragraph

Article in Annals of gastroenterological surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 8 institutions in 1 country.

Takaaki MatsubaraDepartment of Surgery, Division of Lower Gastrointestinal Surgery Hyogo College of Medicine Nishinomiya Hyogo Japan.
Naohito BeppuDepartment of Surgery, Division of Lower Gastrointestinal Surgery Hyogo College of Medicine Nishinomiya Hyogo Japan.ORCID https://orcid.org/0000-0002-5886-3138
Masataka IkedaDepartment of Surgery, Division of Lower Gastrointestinal Surgery Hyogo College of Medicine Nishinomiya Hyogo Japan.ORCID https://orcid.org/0000-0001-9602-6659
Hideyuki IshidaStudy Group for Familial Adenomatous Polyposis in the Japanese Society for Cancer of the Colon and Rectum Tokyo Japan.
Yoji TakeuchiStudy Group for Familial Adenomatous Polyposis in the Japanese Society for Cancer of the Colon and Rectum Tokyo Japan.
Toshiya NagasakiStudy Group for Familial Adenomatous Polyposis in the Japanese Society for Cancer of the Colon and Rectum Tokyo Japan.
Akinari TakaoStudy Group for Familial Adenomatous Polyposis in the Japanese Society for Cancer of the Colon and Rectum Tokyo Japan.
Kazuhito SasakiStudy Group for Familial Adenomatous Polyposis in the Japanese Society for Cancer of the Colon and Rectum Tokyo Japan.
Kiwamu AkagiStudy Group for Familial Adenomatous Polyposis in the Japanese Society for Cancer of the Colon and Rectum Tokyo Japan.
Tomoya SudoStudy Group for Familial Adenomatous Polyposis in the Japanese Society for Cancer of the Colon and Rectum Tokyo Japan.
Hideki UenoStudy Group for Familial Adenomatous Polyposis in the Japanese Society for Cancer of the Colon and Rectum Tokyo Japan.ORCID https://orcid.org/0000-0002-8600-1199
Tatsuro YamaguchiStudy Group for Familial Adenomatous Polyposis in the Japanese Society for Cancer of the Colon and Rectum Tokyo Japan.ORCID https://orcid.org/0000-0001-8454-1995
Naohiro TomitaStudy Group for Familial Adenomatous Polyposis in the Japanese Society for Cancer of the Colon and Rectum Tokyo Japan.
Yoichi AjiokaStudy Group for Familial Adenomatous Polyposis in the Japanese Society for Cancer of the Colon and Rectum Tokyo Japan.
Japan Cancer Society · JPHyogo Medical University · JPTokyo Metropolitan Komagome Hospital · JPKurume University · JPOsaka International Cancer Institute · JPSaitama Cancer Center · JPSocial Insurance Saitama Chuo Hospital · JPToyonaka Municipal Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: In Japanese patients with familial adenomatous polyposis (FAP), colectomy tends to be postponed or avoided. Aim: This study aimed to clarify the current clinical practice from a Japanese multicenter cohort study database. Methods: We analyzed the records of 250 patients with non-dense FAP who did not require colorectal cancer removal. The clinical outcomes were compared between patients who received colectomy (n = 142) (Group A) and those who did not receive colectomy (n = 108) (Group B). Results: The colectomy rate based on the age at the final follow-up examination was 46%, 60%, 54%, 65%, at ≤29, 30-39, 40-49, and ≥ 50 years, respectively ( Conclusion: Over one-third of patients with non-dense FAP (polyps ≤ 1000) in Japan did not receive colectomy at >30 years of age, and patients who managed without colectomy showed acceptable survival with the early diagnosis of colorectal cancer, and a very low incidence of desmoid tumor development, indicating that this approach represents a potential option for the management of selected non-dense FAP patients.

Indexed as

colorectal cancerdesmoid tumorsfamilial adenomatous polyposisnon‐colectomy

Identifiers

PMID36338590
PMCPMC9628228
OpenAlexW4281386529

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.