Evidence map›Paper›PMID 36338409›Full record

ArticleJACC. Asia2022

Longitudinal Quantitative Assessment of Coronary Atherosclerotic Plaque Burden Related to Serum Hemoglobin Levels.

Ki-Bum Won, Byoung Kwon Lee, Ran Heo, Hyung-Bok Park, Fay Y Lin, Martin Hadamitzky, Yong-Jin Kim, Ji Min Sung, Edoardo Conte, Daniele Andreini and 20 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in JACC. Asia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02803411 (Progression of AtheRosclerotic PlAque DetermIned by Computed TomoGraphic Angiography Imaging), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02803411 unknown statusnot on this map

Progression of AtheRosclerotic PlAque DetermIned by Computed TomoGraphic Angiography Imaging(PARADIGM)

Typeobservational_patient_registrySponsorYonsei UniversityRan2003 to 2026Enrolled2,000ConditionsCoronary Heart Disease
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors at 20 institutions in 8 countries.

Ki-Bum WonCardiovascular Center, Dongguk University Ilsan Hospital, Goyang, South Korea.
Byoung Kwon LeeDepartment of Cardiology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, South Korea.
Ran HeoYonsei-Cedars-Sinai Integrative Cardiovascular Imaging Research Center, Yonsei University Health System, Seoul, South Korea.
Hyung-Bok ParkYonsei-Cedars-Sinai Integrative Cardiovascular Imaging Research Center, Yonsei University Health System, Seoul, South Korea.
Fay Y LinDepartment of Radiology, New York-Presbyterian Hospital and Weill Cornell Medicine, New York, New York, USA.
Martin HadamitzkyDepartment of Radiology and Nuclear Medicine, German Heart Center Munich, Munich, Germany.
Yong-Jin KimDivision of Cardiology, Seoul National University College of Medicine, Cardiovascular Center, Seoul National University Hospital, Seoul, South Korea.
Ji Min SungDepartment of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Seoul, South Korea.
Edoardo ConteCentro Cardiologico Monzino, IRCCS, Milan, Italy.
Daniele AndreiniCentro Cardiologico Monzino, IRCCS, Milan, Italy.
Gianluca PontoneCentro Cardiologico Monzino, IRCCS, Milan, Italy.
Matthew J BudoffDepartment of Medicine, Lundquist Institute at Harbor UCLA Medical Center, Torrance, California, USA.
Ilan GottliebDepartment of Radiology, Casa de Saude São Jose, Rio de Janeiro, Brazil.
Eun Ju ChunSeoul National University Bundang Hospital, Sungnam, South Korea.
Filippo CademartiriCardiovascular Imaging Center, SDN IRCCS, Naples, Italy.
Erica MaffeiDepartment of Radiology, Area Vasta 1/ASUR Marche, Urbino, Italy.
Hugo MarquesUNICA, Unit of Cardiovascular Imaging, Hospital da Luz, Lisbon, Portugal.
Pedro de Araújo GonçalvesUNICA, Unit of Cardiovascular Imaging, Hospital da Luz, Lisbon, Portugal.
Jonathon A LeipsicDepartment of Medicine and Radiology, University of British Columbia, Vancouver, British Columbia, Canada.
Sang-Eun LeeYonsei-Cedars-Sinai Integrative Cardiovascular Imaging Research Center, Yonsei University Health System, Seoul, South Korea.
Sanghoon ShinYonsei-Cedars-Sinai Integrative Cardiovascular Imaging Research Center, Yonsei University Health System, Seoul, South Korea.
Jung Hyun ChoiDepartment of Cardiology, Pusan University Hospital, Busan, South Korea.
Renu VirmaniDepartment of Pathology, CVPath Institute, Gaithersburg, Maryland, USA.
Habib SamadyDepartment of Cardiology, Emory University School of Medicine, Atlanta, Georgia, USA.
Kavitha ChinnaiyanDepartment of Cardiology, William Beaumont Hospital, Royal Oak, Michigan, USA.
Daniel S BermanDepartment of Imaging and Medicine, Cedars Sinai Medical Center, Los Angeles, California, USA.
Jagat NarulaIcahn School of Medicine at Mount Sinai, Mount Sinai Heart, Zena and Michael A. Wiener Cardiovascular Institute, and Marie-Josée and Henry R. Kravis Center for Cardiovascular Health, New York, New York, USA.
Jeroen J BaxDepartment of Cardiology, Leiden University Medical Center, Leiden, the Netherlands.
James K MinDepartment of Radiology, New York-Presbyterian Hospital and Weill Cornell Medicine, New York, New York, USA.
Hyuk-Jae ChangDepartment of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Seoul, South Korea.
Gangnam Severance Hospital · KRCentro Cardiologico Monzino · ITYonsei University Health System · KRBeaumont Hospital, Royal Oak · USCatholic Kwandong University · KRCedars-Sinai Medical Center · USCVPath Institute · USDeutsches Herzzentrum München · DEEmory University · USHanyang University Seoul Hospital · KRHospital da Luz · PTIcahn School of Medicine at Mount Sinai · USLeiden University Medical Center · NLPresbyterian Hospital · USPusan National University Hospital · KRSDN Istituto di Ricerca Diagnostica e Nucleare · ITSeoul National University Bundang Hospital · KRSeoul National University Hospital · KRUCLA Medical Center · USUniversidade Nova de Lisboa · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Despite a potential role of hemoglobin in atherosclerosis, data on coronary plaque volume changes (PVC) related to serum hemoglobin levels are limited. Objectives: The authors sought to evaluate coronary atherosclerotic plaque burden changes related to serum hemoglobin levels using serial coronary computed tomographic angiography (CCTA). Methods: A total of 830 subjects (age 61 ± 10 years, 51.9% male) who underwent serial CCTA were analyzed. The median interscan period was 3.2 (IQR: 2.5-4.4) years. Quantitative assessment of coronary plaques was performed at both scans. All participants were stratified into 4 groups based on the quartile of baseline hemoglobin levels. Annualized total PVC (mm Results: Baseline total plaque volume (mm Conclusions: Serial CCTA findings suggest that Δ hemoglobin has an independent effect on coronary atherosclerosis. This effect might be influenced by baseline hemoglobin levels. (Progression of Atherosclerotic Plaque Determined by Computed Tomographic Angiography Imaging [PARADIGM]; NCT02803411).

Indexed as

atherosclerosisCCTA, coronary computed tomographic angiographycoronary computed tomography angiographyCV, cardiovascularhemoglobinPVC, plaque volume changesΔ hemoglobin, hemoglobin level changes

Identifiers

PMID36338409
PMCPMC9627907
OpenAlexW4223433235

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.