ArticleJACC. Asia2022
Distribution, Characteristics, and Management of Older Patients With Valvular Heart Disease in China: China-DVD Study.
Article in JACC. Asia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 4 of them syntheses that pooled it.
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Who cites it
60 citing papers in PubMed, 4 syntheses or guidelines pooled it, 73 citations in OpenAlex.
- Iatrogenic atrial septal defect following transcatheter edge-to-edge mitral valve repair: A systematic review and meta-analysis.Medicine · 2025Pooled it
- Comparative outcomes of on-label and off-label transcatheter aortic valve replacement for aortic regurgitation: a systematic review and meta-analysis.Open heart · 2025Pooled it
- Pooled it
- Single arm meta-analysis of the J-Valve system for aortic regurgitation in Chinese populations.Frontiers in cardiovascular medicine · 2025Pooled it
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- Aortic valve disease: Novel animal models for advancing our understanding of the underlying mechanisms.Animal models and experimental medicine · 2026Review
- Structural Optimization and Fatigue Performance Evaluation of Balloon-Expandable Aortic Valve Stents.Materials (Basel, Switzerland) · 2026Article
- Novel Transcatheter Edge-to-Edge Repair System for Degenerative Mitral Regurgitation: 1-Year Outcomes.JACC. Asia · 2026Article
- Association Between Stress Hyperglycemia Ratio and Death in Patients With Moderate to Severe Tricuspid Regurgitation.Journal of the American Heart Association · 2026Observational
- A Case of Venous Tissue Dissection During Transcatheter MitraClip Surgery.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026Article
- Impact of RAS inhibitors on 2-year mortality and disease progression in chronic mitral regurgitation.BMC cardiovascular disorders · 2026Article
- Technological Innovations and Research Frontiers in Interventional Therapy for Mitral Regurgitation.Reviews in cardiovascular medicine · 2026Review
- Plasma aldosterone concentration and valvular heart disease in hypertensive patients: a large cross-sectional study.Scientific reports · 2026Article
- Clinical efficacy of transcatheter aortic valve replacement in patients with rheumatic aortic stenosis.BMC cardiovascular disorders · 2026Article
- Exclusion of the left atrial appendage in Chinese population with perclip system: 1-year follow-up outcome results from a prospective, multi-center, open-label, single-arm device trial.Journal of cardiothoracic surgery · 2026Article
- Probing the Relationship Between Perioperative Complications in Patients With Valvular Heart Disease: Network Analysis Based on Bayesian Network.JMIR formative research · 2025Article
- COMPERA 2.0 risk stratification in patients with severe aortic stenosis: implication for group 2 pulmonary hypertension.Journal of Zhejiang University. Science. B · 2025Article
- Knockdown of PARM1 Alleviates Aortic Valve Calcification via the PRKCH-MAPK Signaling Pathway.JACC. Basic to translational science · 2025Article
- Transcatheter Aortic Valve Replacement for Pure Aortic Regurgitation: Dedicated Technique or Dedicated Device?JACC. Asia · 2025Article
- Protective functions of liver X receptor α on calcified aortic valve: involvement of regulating endoplasmic reticulum-mediated osteogenic differentiation.Cardiovascular research · 2025Article
Corrections and comments
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Authors and funding
13 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The epidemiology and management of valvular heart disease (VHD) have changed with economic development and population aging in China in recent decades. Objectives: This study sought to understand the distribution, etiology, and presentation and assess the current practice and outcomes of older patients with VHD in China. Methods: The authors conducted the first nationwide survey of older patients with VHD between September and December 2016 from 69 hospitals in 28 provinces and municipalities throughout China. Hospitalized patients over 60 years of age with moderate-to-severe VHD, infective endocarditis, or previous valvular intervention were consecutively enrolled. Results: Of 8,929 patients (median age of 69 years, 47.5% female), 8227 (92.1%) had native VHD. Mitral regurgitation was the most prevalent single VHD (26.9% of native VHD), followed by tricuspid regurgitation (16.5%), aortic regurgitation (10.6%), aortic stenosis (5.1%), and mitral stenosis (3.1%). Degenerative (37.2%), functional (21.8%), and rheumatic (15.0%) etiologies were the 3 most common causes. Among symptomatic patients with severe VHD, 37.3% underwent valvular intervention. The intervention rates decreased significantly with age across all types of VHD ( Conclusions: This study provides a unique national insight into the contemporary spectrum and management of older VHD patients in China. With the increase in the health care demand, more resources and efforts are required for early detection, effective intervention, and targeting innovation on advanced therapeutic techniques and devices to improve the outcomes.
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