Evidence map›Paper›PMID 36338359›Full record

ArticleJACC. Asia2021

Prognostic Implications of Comprehensive Whole Vessel Plaque Quantification Using Coronary Computed Tomography Angiography.

Seokhun Yang, Joo Myung Lee, Masahiro Hoshino, Tadashi Murai, Ki Hong Choi, Doyeon Hwang, Kyung-Jin Kim, Eun-Seok Shin, Joon-Hyung Doh, Hyuk-Jae Chang and 9 more

Registry-linked trialAbstract read
In one paragraph

Article in JACC. Asia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04037163 (CCTA-FFR Registry for Development of Comprehensive Risk Prediction Model), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04037163 completednot on this map

CCTA-FFR Registry for Development of Comprehensive Risk Prediction Model

TypeobservationalSponsorSeoul National University HospitalRan2010 to 2019Enrolled747ConditionsCoronary Artery DiseaseArmsFractional flow reserve, Coronary CT angiography
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Seokhun YangDepartment of Internal Medicine and Cardiovascular Center, Seoul National University Hospital, Seoul, Korea.
Joo Myung LeeDivision of Cardiology, Department of Internal Medicine, Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Masahiro HoshinoDivision of Cardiovascular Medicine, Tsuchiura Kyodo General Hospital, Ibaraki, Japan.
Tadashi MuraiDivision of Cardiovascular Medicine, Tsuchiura Kyodo General Hospital, Ibaraki, Japan.
Ki Hong ChoiDivision of Cardiology, Department of Internal Medicine, Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Doyeon HwangDepartment of Internal Medicine and Cardiovascular Center, Seoul National University Hospital, Seoul, Korea.
Kyung-Jin KimDepartment of Internal Medicine, Ewha Womans University Medical Center, Ewha Womans University School of Medicine, Seoul, Korea.
Eun-Seok ShinDepartment of Cardiology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea and Division of Cardiology, Ulsan Hospital, Ulsan, Korea.
Joon-Hyung DohDepartment of Medicine, Inje University Ilsan Paik Hospital, Goyang, Korea.
Hyuk-Jae ChangDivision of Cardiology, Severance Cardiovascular Hospital, Yonsei-Cedars-Sinai Integrative Cardiovascular Imaging Research Center, Yonsei University College of Medicine, Seoul, Korea.
Chang-Wook NamDepartment of Medicine, Keimyung University Dongsan Medical Center, Daegu, Korea.
Jinlong ZhangDepartment of Cardiology, The Second Affiliated Hospital, School of Medicine, Zhejiang University, China.
Jianan WangDepartment of Cardiology, The Second Affiliated Hospital, School of Medicine, Zhejiang University, China.
Shao-Liang ChenDepartment of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Nobuhiro TanakaDepartment of Cardiology, Tokyo Medical University, Tokyo, Japan.
Hitoshi MatsuoDepartment of Cardiology, Gifu Heart Center, Gifu, Japan.
Takashi AkasakaWakayama Medical University, Wakayama, Japan.
Tsunekazu KakutaDivision of Cardiovascular Medicine, Tsuchiura Kyodo General Hospital, Ibaraki, Japan.
Bon-Kwon KooDepartment of Internal Medicine and Cardiovascular Center, Seoul National University Hospital, Seoul, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The prognostic value of whole vessel plaque quantification has not been fully understood. Objectives: We aimed to investigate the clinical relevance of whole vessel plaque quantification on coronary computed tomography angiography. Methods: In a total of 1,013 vessels with fractional flow reserve (FFR) measurement and available coronary computed tomography angiography, high-risk plaque characteristics (HRPC) included minimum lumen area <4 mm Results: Whole vessel plaque quantification had incremental predictability in addition to % diameter stenosis and HRPC ( Conclusions: Whole vessel plaque quantification can provide incremental predictability for low FFR and additive prognostic value in deferred vessels with high FFR over anatomical severity and lesion plaque characteristics. (CCTA-FFR Registry for Risk Prediction; NCT04037163).

Indexed as

atherosclerosisCAD, coronary artery diseasecoronary CT angiographyCTA, computed tomography angiographyFFNC, fibrofatty and necrotic coreFFR, fractional flow reservefractional flow reserveHRPC, high-risk plaque characteristicsHRVC, high-risk vessel characteristicsMLA, minimum lumen areaplaque quantificationVOCO, vessel-oriented composite outcome

Identifiers

PMID36338359
PMCPMC9627853

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.