Evidence map›Paper›PMID 36338183›Full record

ArticleJournal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada2020

Defining appropriate antibiotic prescribing in primary care: A modified Delphi panel approach.

Julie Hui-Chih Wu, Bradley Langford, Rita Ha, Gary Garber, Nick Daneman, Jennie Johnstone, Warren McIsaac, Sally Sharpe, Karen Tu, Kevin L Schwartz

Open access · greenAbstract read
In one paragraph

Article in Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

  1. Canada's "American-style" dental health system.Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2025
    Article
  2. Article
  3. Quality of Antibiotic Prescribing for Outpatient Cystitis in Adult Females.Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2024
    Article
  4. Do family medicine residents optimally prescribe antibiotics for common infectious conditions seen in a primary care setting?Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Julie Hui-Chih WuPublic Health Ontario, Toronto, Ontario, Canada.
Bradley LangfordPublic Health Ontario, Toronto, Ontario, Canada.
Rita HaPublic Health Ontario, Toronto, Ontario, Canada.
Gary GarberPublic Health Ontario, Toronto, Ontario, Canada.
Nick DanemanPublic Health Ontario, Toronto, Ontario, Canada.
Jennie JohnstonePublic Health Ontario, Toronto, Ontario, Canada.
Warren McIsaacDepartment of Family and Community Medicine, University of Toronto, Toronto, Ontario, Canada.
Sally SharpeFour Villages Community Health Centre, Toronto, Ontario, Canada.
Karen TuFaculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Kevin L SchwartzPublic Health Ontario, Toronto, Ontario, Canada.
Public Health Ontario · CAUniversity of Toronto · CARegent Park Community Health Centre · CASinai Health System · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Antimicrobial overuse contributes to antimicrobial resistance. In the ambulatory setting, where more than 90% of antibiotics are dispensed, there are no Canadian benchmarks for appropriate use. This study aims to define the expected appropriate outpatient antibiotic prescribing rates for three age groups (<2, 2-18, >18 years) using a modified Delphi method. Methods: We developed an online questionnaire to solicit from a multidisciplinary panel (community-academic family physicians, adult-paediatric infectious disease physicians, and antimicrobial stewardship pharmacists) what percentage of 23 common clinical conditions would appropriately be treated with systemic antibiotics followed with in-person meetings to achieve 100% consensus. Results: The panelists reached consensus for one condition online and 22 conditions face-to-face, which took an average of 2.6 rounds of discussion per condition (range, min-max 1-5). The consensus for appropriate systemic antibiotic prescribing rates were, for pneumonia, pyelonephritis, non-purulent skin and soft tissue infections (SSTI), other bacterial infections, and reproductive tract infections, 100%; urinary tract infections, 95%-100%; prostatitis, 95%; epididymo-orchitis, 85%-88%; chronic obstructive pulmonary disease, 50%; purulent SSTI, 35%-50%; otitis media, 30%-40%; pharyngitis, 18%-40%; acute sinusitis, 18%-20%; chronic sinusitis, 14%; bronchitis, 5%-8%; gastroenteritis, 4%-5%; dental infections, 4%; eye infections, 1%; otitis externa, 0%-1%; and asthma, common cold, influenza, and other non-bacterial infections (0%). (Note that some differed by age group.). Conclusions: This study resulted in expert consensus for defined levels of appropriate antibiotic prescribing across a broad set of outpatient conditions. These results can be applied to community antimicrobial stewardship initiatives to investigate the level of inappropriate use and set targets to optimize antibiotic use.

Indexed as

ambulatoryantibiotic stewardshipantimicrobial resistanceantimicrobial stewardshipappropriate antibiotic prescribingappropriate antimicrobial prescribingcommunityoutpatientprimary care

Identifiers

PMID36338183
PMCPMC9602887
OpenAlexW3006943567

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.