Evidence map›Paper›PMID 36338161›Full record

ArticleJACC. Asia2021

Lowering the Recommended Maximal Wall Thickness Threshold Improves Diagnostic Sensitivity in Asians With Hypertrophic Cardiomyopathy.

Thu-Thao Le, Benjamin Huang, Chee Jian Pua, Vineet Tornekar, Annette Schumacher-Maurer, Desiree-Faye Toh, Jennifer Bryant, Briana Ang, Ben Corden, Sanjay K Prasad and 3 more

Open access · goldAbstract read
In one paragraph

Article in JACC. Asia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Thu-Thao LeDepartment of Cardiology, National Heart Centre Singapore, Singapore.
Benjamin HuangDepartment of Cardiology, National Heart Centre Singapore, Singapore.
Chee Jian PuaDepartment of Cardiology, National Heart Centre Singapore, Singapore.
Vineet TornekarDepartment of Cardiology, National Heart Centre Singapore, Singapore.
Annette Schumacher-MaurerDepartment of Cardiology, National Heart Centre Singapore, Singapore.
Desiree-Faye TohDepartment of Cardiology, National Heart Centre Singapore, Singapore.
Jennifer BryantDepartment of Cardiology, National Heart Centre Singapore, Singapore.
Briana AngDepartment of Cardiology, National Heart Centre Singapore, Singapore.
Ben CordenDepartment of Cardiology, National Heart Centre Singapore, Singapore.
Sanjay K PrasadNational Heart and Lung Institute, Imperial College, London, United Kingdom.
Hak-Chiaw TangDepartment of Cardiology, National Heart Centre Singapore, Singapore.
Stuart A CookDepartment of Cardiology, National Heart Centre Singapore, Singapore.
Calvin W L ChinDepartment of Cardiology, National Heart Centre Singapore, Singapore.
National Heart Centre Singapore · SGDuke-NUS Medical School · SGImperial College London · GBNational University of Singapore · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Hypertrophic cardiomyopathy (HCM) is defined as left ventricular end-diastolic maximal wall thickness (WT Objectives: This study aims to examine the implications of this single absolute WT Methods: The study consisted of 360 healthy volunteers (male: n = 174; age: 50 ± 12 years) and 114 genetically characterized patients with HCM (male: n = 83; age: 52 ± 13 years; genotype-positive, n = 39). All participants underwent cardiovascular magnetic resonance. WT Results: Healthy male volunteers had increased WT Conclusions: The study highlights cautious application of guideline-recommended WT

Indexed as

asymmetrical hypertrophyAUC, area under the curvecardiovascular magnetic resonanceCMR, cardiovascular magnetic resonanceHCM, hypertrophic cardiomyopathyhypertrophic cardiomyopathyLVH, left ventricular hypertrophyLV, left ventricle/left ventricularNPV, negative predictive valuePPV, positive predictive valuesex-specific diagnostic thresholdsWTMax, maximal wall thickness

Identifiers

PMID36338161
PMCPMC9627927
OpenAlexW3201549479

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.