Evidence map›Paper›PMID 36338156›Full record

ArticleJACC. Asia2021

Validation of the Khorana Venous Thromboembolism Risk Score in Japanese Cancer Patients.

Fumie Akasaka-Kihara, Daisuke Sueta, Masanobu Ishii, Yuji Maki, Kyoko Hirakawa, Noriaki Tabata, Miwa Ito, Kenshi Yamanaga, Koichiro Fujisue, Tadashi Hoshiyama and 15 more

Open access · goldAbstract read
In one paragraph

Article in JACC. Asia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 2 institutions in 1 country.

Fumie Akasaka-KiharaDepartment of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto, Japan.
Daisuke SuetaDepartment of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto, Japan.
Masanobu IshiiDepartment of Cardiology, Miyazaki Prefectural Nobeoka Hospital, Nobeoka, Japan.
Yuji MakiDepartment of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto, Japan.
Kyoko HirakawaDepartment of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto, Japan.
Noriaki TabataDepartment of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto, Japan.
Miwa ItoDepartment of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto, Japan.
Kenshi YamanagaDepartment of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto, Japan.
Koichiro FujisueDepartment of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto, Japan.
Tadashi HoshiyamaDepartment of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto, Japan.
Shinsuke HanataniDepartment of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto, Japan.
Hisanori KanazawaDepartment of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto, Japan.
Seiji TakashioDepartment of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto, Japan.
Yuichiro ArimaDepartment of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto, Japan.
Satoshi ArakiDepartment of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto, Japan.
Hiroki UsukuDepartment of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto, Japan.
Taishi NakamuraDepartment of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto, Japan.
Satoru SuzukiDepartment of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto, Japan.
Eiichiro YamamotoDepartment of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto, Japan.
Hirofumi SoejimaDepartment of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto, Japan.
Koichi KaikitaDepartment of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto, Japan.
Kenichi MatsushitaDepartment of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto, Japan.
Masao MatsuokaDepartment of Hematology, Rheumatology, and Infectious Diseases, Kumamoto University School of Medicine, Kumamoto Japan.
Koichiro UsukuDepartment of Medical Information Science and Administration Planning, Kumamoto University Hospital, Kumamoto Japan.
Kenichi TsujitaDepartment of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto, Japan.
Kumamoto University · JPMiyazaki Prefectural Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Although the Khorana venous thromboembolism (VTE) risk score (KRS) is well recognized as a simple VTE risk assessment method in patients with cancer, whether it is suitable for Asian populations is unclear. Objectives: This study validated KRS for the prediction of VTE and investigated the value of the KRS in predicting mortality in Japanese patients with cancer. Methods: A body mass index value of 25 kg/m Results: The prevalence of VTE was 1.7%, 7.3%, and 11.0% for low-, intermediate-, and high-score patients, respectively. Receiver operating characteristic (ROC) analysis showed that the KRS significantly predicted VTE (area under the curve, 0.679; 95% confidence interval [CI] 0.666-0.692; Conclusions: The KRS was useful in Japanese patients with cancer and might be a potentially useful marker for the prediction of mortality. Establishing optimal scores for Japanese subjects is mandatory because of its low diagnostic ability. (KUMAMON Cancer registry; UMIN000047554).

Indexed as

AUC, area under the curveBMI, body mass indexcancerCAT, cancer-associated thrombosisCI, confidence intervalCKD, chronic kidney diseaseDL, dyslipidemiaDM, diabetes mellitusHT, hypertensionICD, International Classification of DiseasesKhorana VTE risk scoreKRS, Khorana venous thromboembolism risk scoremortalityrisk stratificationROC, receiver-operating characteristicvenous thromboembolismVTE, venous thromboembolism

Identifiers

PMID36338156
PMCPMC9627826
OpenAlexW3201543724

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.