Evidence map›Paper›PMID 36337927›Full record

ArticleJACC. Basic to translational science2022

TNFR1 Contributes to Activation-Induced Cell Death of Pathological CD4

Vinay Kumar, Rachel Rosenzweig, Suman Asalla, Sarita Nehra, Sumanth D Prabhu, Shyam S Bansal

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JACC. Basic to translational science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 44 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Vinay KumarDepartment of Physiology and Cell Biology, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Rachel RosenzweigDepartment of Physiology and Cell Biology, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Suman AsallaDepartment of Physiology and Cell Biology, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Sarita NehraDepartment of Physiology and Cell Biology, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Sumanth D PrabhuDivision of Cardiology, Department of Medicine, Washington University, St Louis, Missouri, USA.
Shyam S BansalDepartment of Physiology and Cell Biology, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
The Ohio State University Wexner Medical Center · USWashington University in St. Louis · US

Funding

Macrophage Circadian Clock Disruption and Inflammation in Heart FailureR01HL147549 · NHLBI · WASHINGTON UNIVERSITY · PI PRABHU, SUMANTH D, YOUNG, MARTIN E · 2019 to 2022
$2.3M
Cardiac Macrophages as Disease Drivers in Chronic Ischemic Heart FailureR01HL157999 · NHLBI · WASHINGTON UNIVERSITY · PI PRABHU, SUMANTH D · 2021 to 2024
$2.1M
Splenic Marginal Zone Macrophages in Chronic Ischemic Heart FailureR01HL125735 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI PRABHU, SUMANTH D · 2015 to 2018
$1.5M
Role of Regulatory T-Lymphocytes in Chronic Heart FailureI01BX002706 · VA · BIRMINGHAM VA MEDICAL CENTER · PI PRABHU, SUMANTH D · 2015 to 2018
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BLRD VA I01 BX002706NHLBI NIH HHS R01 HL125735NHLBI NIH HHS R01 HL147549NHLBI NIH HHS R01 HL157999
6 · The paper itself

Abstract

CD4

Indexed as

AT, adoptive transferheart failureHF, heart failureIL, interleukinleft ventricular remodelingLV, left ventricularMFI, mean fluorescence intensityMI, myocardial infarctionmLN, mediastinal lymph nodemyocardial infarctionPBS, phosphate-buffered salineTcm, memory T cellTCR, T-cell receptorT lymphocytesTNFR1, tumor necrosis factor receptor 1TNF, tumor necrosis factortumor necrosis factor receptorsWT, wild type

Identifiers

PMID36337927
PMCPMC9626895
OpenAlexW4286636716

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.