ArticleJACC. Basic to translational science2022
Interstitial Collagen Loss, Myocardial Remodeling, and Function in Primary Mitral Regurgitation.
Article in JACC. Basic to translational science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 17 citations in OpenAlex.
- Persistent Shift in Principal Strain Angles and Postsurgical Decline in Left Ventricular Ejection Fraction in Patients With Primary Mitral Regurgitation.Journal of the American Heart Association · 2025Article
- Whole exome sequencing of 80 cases of sporadic mitral valve prolapse reveals novel disease-associated genes and variants in a Southern Chinese population.Genes & genomics · 2025Article
- Prognostic Implications of Cardiac Magnetic Resonance Imaging Characteristics in Primary Mitral Regurgitation.JACC. Advances · 2025Article
- Association of Systemic Inflammatory Response Syndrome With Cardiovascular Events After Mitral Transcatheter Edge-to-Edge Repair.Journal of the American Heart Association · 2024Article
- Quantitation of mitral regurgitation using positron emission tomography.EJNMMI research · 2024Article
- Assessing Regurgitation Severity, Adverse Remodeling, and Fibrosis with CMR in Primary Mitral Regurgitation.Current cardiology reports · 2024Review
- Gene expression and ultra-structural evidence for metabolic derangement in the primary mitral regurgitation heart.European heart journal open · 2024Article
- Left ventricular fibrosis and CMR tissue characterization of papillary muscles in mitral valve prolapse patients.The international journal of cardiovascular imaging · 2024Article
- Imminent risk of LVEF decline in asymptomatic patients with primary mitral regurgitation.Frontiers in cardiovascular medicine · 2024Article
- Understanding post-surgical decline in left ventricular function in primary mitral regurgitation using regression and machine learning models.Frontiers in cardiovascular medicine · 2023Article
- The Pathology of Primary Mitral Regurgitation: The Matrix Is at the Heart of the Matter.JACC. Basic to translational science · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Interstitial collagen loss and cardiomyocyte ultrastructural damage accounts for left ventricular (LV) sphericity and decrease in LV twist and circumferential strain. Normal LV diastolic function belies significantly abnormal left atrial (LA) function and early LV diastolic untwist rate. This underscores the complex interplay of LV and LA myocardial remodeling and function in the pathophysiology of primary mitral regurgitation. In this study, we connect LA function with LV systolic and diastolic myocardial remodeling and function using cardiac magnetic resonance tissue tagging in primary mitral regurgitation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.