ArticleFrontiers in human neuroscience2022
Association of prenatal modifiable risk factors with attention-deficit hyperactivity disorder outcomes at age 10 and 15 in an extremely low gestational age cohort.
Article in Frontiers in human neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.
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Who cites it
9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.
- Hypertensive disorders of pregnancy and childhood neurodevelopment: A systematic review and meta-analysis.PLoS medicine · 2025Pooled it
- The association between maternal diabetes and the risk of attention deficit hyperactivity disorder in offspring: an updated systematic review and meta-analysis.European child & adolescent psychiatry · 2025Pooled it
- Correction: Implications for the Prevention of Poverty-Related Environmental Risks for Childhood ADHD: A Narrative Review.Child psychiatry and human development · 2026Article
- Implications for the Prevention of Poverty-Related Environmental Risks for Childhood ADHD: A Narrative Review.Child psychiatry and human development · 2026Review
- Exercise therapy for gestational diabetes mellitus: from basic to clinical.Frontiers in medicine · 2025Review
- Association of premature birth and maternal education level on attention deficit hyperactivity disorder in children: A meta-analysis.World journal of psychiatry · 2024Article
- Prenatal Tobacco Exposure and Behavioral Disorders in Children and Adolescents: Systematic Review and Meta-Analysis.Pediatric reports · 2024Review
- Optimizing trajectories of social adaptive competencies after extreme prematurity during the first 1000 days.Seminars in fetal & neonatal medicine · 2024Review
- A Narrative Review of the Association between Prematurity and Attention-Deficit/Hyperactivity Disorder and Accompanying Inequities across the Life-Course.Children (Basel, Switzerland) · 2023Review
Corrections and comments
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Authors and funding
12 authors at 7 institutions in 1 country.
Funding
Abstract
Background: The increased risk of developing attention-deficit hyperactivity disorder (ADHD) in extremely preterm infants is well-documented. Better understanding of perinatal risk factors, particularly those that are modifiable, can inform prevention efforts. Methods: We examined data from the Extremely Low Gestational Age Newborns (ELGAN) Study. Participants were screened for ADHD at age 10 with the Child Symptom Inventory-4 ( Results: Elevated maternal BMI and maternal diabetes were each associated with a 55-65% increase in risk of ADHD, with evidence of both additive and multiplicative interactions between the two exposures. MSDP and HDP were not associated with the risk of ADHD outcomes. There was some evidence for association of ADHD outcomes with high levels of inflammatory proteins or moderate levels of neurotrophic proteins, but there was no evidence that these mediated the risk associated with maternal BMI or diabetes. Conclusion: Contrary to previous population-based studies, MSDP and HDP did not predict ADHD outcomes in this extremely preterm cohort, but elevated maternal pre-pregnancy BMI, maternal diabetes, and perinatal inflammatory markers were associated with increased risk of ADHD at age 10 and/or 15, with positive interaction between pre-pregnancy BMI and maternal diabetes.
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