Evidence map›Paper›PMID 36337377›Full record

ArticleRevista espanola de anestesiologia y reanimacion2022

[Pre-clinical validation of a turbine-based ventilator for invasive ventilation-The ACUTE-19 ventilator].

J M Alonso-Iñigo, G Mazzinari, M Casañ-Pallardó, J I Redondo-García, J Viscasillas-Monteagudo, A Gutierrez-Bautista, J Ramirez-Faz, P Alonso-Pérez, S Díaz-Lobato, A S Neto and 6 more

Open access · greenAbstract readEnglish Abstract
PubMed Full text at PMC Publisher
In one paragraph

Article in Revista espanola de anestesiologia y reanimacion, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 73% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 8 institutions in 10 countries.

J M Alonso-IñigoResearch Group in Perioperative Medicine, Department of Anesthesia, Critical Care and Pain Medicine, Hospital Universitario y Politécnico La Fe, Valencia, España.
G MazzinariDepartment of Anesthesia, Critical Care and Pain Medicine, Hospital General Universitario de Castellón, Castellón de la Plana, Castellón, España.
M Casañ-PallardóDepartment of Anesthesia, Critical Care and Pain Medicine, Hospital General Universitario de Castellón, Castellón de la Plana, Castellón, España.
J I Redondo-GarcíaDepartment of Veterinary Anesthesia, Hospital Clínico Veterinario CEU, Universidad CEU Cardenal Herrera, Alfara del Patriarca, Valencia, España.
J Viscasillas-MonteagudoDepartment of Veterinary Anesthesia, Hospital Clínico Veterinario CEU, Universidad CEU Cardenal Herrera, Alfara del Patriarca, Valencia, España.
A Gutierrez-BautistaDepartment of Veterinary Anesthesia, Hospital Clínico Veterinario CEU, Universidad CEU Cardenal Herrera, Alfara del Patriarca, Valencia, España.
J Ramirez-FazDepartment of Electrical Engineering, Universidad de Córdoba, Córdoba, España.
P Alonso-PérezDepartment of Research and Innovation, Tecnikoa and C&T Fabrication S. L., Alicante, España.
S Díaz-LobatoMedical Division, Nippon Gases HealthCare & Oximesa NG, Madrid, España.
A S NetoDepartment of Critical Care Medicine, Hospital Israelita Albert Einstein, São Paulo, Brasil.
O Diaz-CambroneroResearch Group in Perioperative Medicine, Department of Anesthesia, Critical Care and Pain Medicine, Hospital Universitario y Politécnico La Fe, Valencia, España.
P Argente-NavarroResearch Group in Perioperative Medicine, Department of Anesthesia, Critical Care and Pain Medicine, Hospital Universitario y Politécnico La Fe, Valencia, España.
M Gama de AbreuPulmonary Engineering Group, Department of Anesthesiology and Intensive Care Therapy, Technische Universität Dresden, Dresden, Alemania.
P PelosiPoliclinico San Martino Hospital, IRCCS for Oncology and Neurosciences, Genoa, Italia.
M J SchultzDepartment of Intensive Care & Laboratory of Experimental Intensive Care and Anesthesiology (LEICA), Academic Medical Center, Amsterdam, Países Bajos.
open source smart breathing system ACUTE-19 investigators
Hospital Universitari i Politècnic La Fe · ESUniversidad Cardenal Herrera CEU · ESHospital General Universitari de Castelló · ESAcademic Medical Center · NLTU Dresden · DEUnited Nations Industrial Development Organization · ATUniversity of Córdoba · ESUniversity of Genoa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The severe acute respiratory syndrome-coronavirus 2 pandemic pressure on healthcare systems can exhaust ventilator resources, especially where resources are restricted. Our objective was a rapid preclinical evaluation of a newly developed turbine-based ventilator, named the ACUTE-19, for invasive ventilation. Methods: Validation consisted of (a) testing tidal volume delivery in 11 simulated models, with various resistances and compliances; (b) comparison with a commercial ventilator (VIVO-50) adapting the United Kingdom Medicines and Healthcare products Regulatory Agency-recommendations for rapidly manufactured ventilators; and (c) Results: Differences in tidal volume in the simulated models were marginally different (largest difference 33 ml [95% CI 31 to 36]; Conclusions: The ACUTE-19 performed accurately in simulated and animal models yielding a comparable performance with a VIVO-50 commercial device. The ACUTE-19 can provide the basis for the development of a future affordable commercial ventilator.

Indexed as

Bench studyCOVID-19Mechanical ventilationMedical capacity surgeSARS-CoV-2Ventilator performance

Identifiers

PMID36337377
PMCPMC9617684
OpenAlexW4200222163

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.