Evidence map›Paper›PMID 36337341›Full record

ArticleBrain communications2022

Structural cerebellar reserve positively influences outcome after severe stroke.

Fatemeh Sadeghihassanabadi, Benedikt M Frey, Winifried Backhaus, Chi-Un Choe, Simone Zittel, Gerhard Schön, Marlene Bönstrup, Bastian Cheng, Götz Thomalla, Christian Gerloff and 1 more

Open access · goldAbstract read
In one paragraph

Article in Brain communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
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  4. Article
  5. Article
  6. Review
  7. Article
  8. Consensus Paper: Cerebellum and Ageing.Cerebellum (London, England) · 2024
    Review
  9. Article
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Fatemeh SadeghihassanabadiDepartment of Neurology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Benedikt M FreyDepartment of Neurology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Winifried BackhausDepartment of Neurology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Chi-Un ChoeDepartment of Neurology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Simone ZittelDepartment of Neurology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Gerhard SchönInstitute of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Marlene BönstrupDepartment of Neurology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.ORCID https://orcid.org/0000-0002-7237-1359
Bastian ChengDepartment of Neurology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.ORCID https://orcid.org/0000-0003-2434-1822
Götz ThomallaDepartment of Neurology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.ORCID https://orcid.org/0000-0002-4785-1449
Christian GerloffDepartment of Neurology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Robert SchulzDepartment of Neurology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Universität Hamburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The concept of brain reserve capacity positively influencing the process of recovery after stroke has been continuously developed in recent years. Global measures of brain health have been linked with a favourable outcome. Numerous studies have evidenced that the cerebellum is involved in recovery after stroke. However, it remains an open question whether characteristics of cerebellar anatomy, quantified directly after stroke, might have an impact on subsequent outcome after stroke. Thirty-nine first-ever ischaemic non-cerebellar stroke patients underwent MRI brain imaging early after stroke and longitudinal clinical follow-up. Structural images were used for volumetric analyses of distinct cerebellar regions. Ordinal logistic regression analyses were conducted to associate cerebellar volumes with functional outcome 3-6 months after stroke, operationalized by the modified Rankin Scale. Larger volumes of cerebellar lobules IV, VI, and VIIIB were positively correlated with favourable outcome, independent of the severity of initial impairment, age, and lesion volume (

Indexed as

capacitycerebellumlobulesreservevolumetry

Identifiers

PMID36337341
PMCPMC9629400
OpenAlexW4289754789

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.