Evidence map›Paper›PMID 36337155›Full record

ReviewWorld journal of stem cells2022

Therapeutic applications of adipose-derived stromal vascular fractions in osteoarthritis.

Qi Tang, Xian-Sheng Zhao, Ao Guo, Ruo-Tong Cui, Huai-Le Song, Zi-Yang Qi, Yi Pan, Yue Yang, Fang-Fang Zhang, Liang Jin

Open access · hybridAbstract readReview
In one paragraph

Review in World journal of stem cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Qi TangSchool of Life Science and Technology, China Pharmaceutical University, Nanjing 211198, Jiangsu Province, China.
Xian-Sheng ZhaoDepartment of Dermatology, Huashan Hospital, Fudan University, Shanghai 200040, China.
Ao GuoSchool of Life Science and Technology, China Pharmaceutical University, Nanjing 211198, Jiangsu Province, China.
Ruo-Tong CuiSchool of Life Science and Technology, China Pharmaceutical University, Nanjing 211198, Jiangsu Province, China.
Huai-Le SongSchool of Life Science and Technology, China Pharmaceutical University, Nanjing 211198, Jiangsu Province, China.
Zi-Yang QiSchool of Life Science and Technology, China Pharmaceutical University, Nanjing 211198, Jiangsu Province, China.
Yi PanSchool of Life Science and Technology, China Pharmaceutical University, Nanjing 211198, Jiangsu Province, China.
Yue YangSchool of Life Science and Technology, China Pharmaceutical University, Nanjing 211198, Jiangsu Province, China.
Fang-Fang ZhangSchool of Life Science and Technology, China Pharmaceutical University, Nanjing 211198, Jiangsu Province, China.
Liang JinSchool of Life Science and Technology, China Pharmaceutical University, Nanjing 211198, Jiangsu Province, China. ljstemcell@cpu.edu.cn.
China Pharmaceutical University · CNHuashan Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteoarthritis (OA) is considered to be a highly heterogeneous disease with progressive cartilage loss, subchondral bone remodeling, and low-grade inflammation. It is one of the world's leading causes of disability. Most conventional clinical treatments for OA are palliative drugs, which cannot fundamentally cure this disease. The stromal vascular fraction (SVF) from adipose tissues is a heterogeneous cell population. According to previous studies, it contains a large number of mesenchymal stem cells, which have been used to treat OA with good therapeutic results. This safe, simple, and effective therapy is expected to be applied and promoted in the future. In this paper, the detailed pathogenesis, diagnosis, and current clinical treatments for OA are introduced. Then, clinical studies and the therapeutic mechanism of SVF for the treatment of OA are summarized.

Indexed as

ArthritisArticular cartilageCell therapyMesenchymal stem cellsStromal vascular fraction

Identifiers

PMID36337155
PMCPMC9630988
OpenAlexW4307057267

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.