ArticleJournal of fluid mechanics2022
A one-dimensional model for the pulsating flow of cerebrospinal fluid in the spinal canal.
Article in Journal of fluid mechanics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 26 citations in OpenAlex.
- How brain pulsations drive solute transport in the cranial subarachnoid space: insights from a toy model.Journal of the Royal Society, Interface · 2026Article
- Patient-specific CFD modeling of CSF flow in Chiari I malformation: denticulate-ligament-induced compartmentalization explains flow patterns.Fluids and barriers of the CNS · 2026Article
- A 3D non-human primate digital model for pharmacokinetic prediction of intra-cerebrospinal fluid drug neuraxial dispersion.Fluids and barriers of the CNS · 2025Article
- Effects of buoyancy on the dispersion of drugs released intrathecally in the spinal canal.Journal of fluid mechanics · 2024Article
- Neurofluids and the glymphatic system: anatomy, physiology, and imaging.The British journal of radiology · 2023Review
- Stationary flow driven by non-sinusoidal time-periodic pressure gradients in wavy-walled channels.Applied mathematical modelling · 2023Article
- Comparison of rostral spread of lumbosacral epidural volume calculated by body weight or length of the vertebral column in small-sized anesthetized dogs.Canadian journal of veterinary research = Revue canadienne de recherche veterinaire · 2023Article
- Rostral spread of lumbosacral epidural volumes of dye and contrast medium calculated using body weight or length of the vertebral column in dog cadavers.Canadian journal of veterinary research = Revue canadienne de recherche veterinaire · 2023Article
- Article
- Oscillating viscous flow past a streamwise linear array of circular cylinders.Journal of fluid mechanics · 2023Article
- Cerebrospinal Fluid Flow.Annual review of fluid mechanics · 2023Article
- Buoyancy-modulated Lagrangian drift in wavy-walled vertical channels as a model problem to understand drug dispersion in the spinal canal.Journal of fluid mechanics · 2022Article
- Effect of Normal Breathing on the Movement of CSF in the Spinal Subarachnoid Space.AJNR. American journal of neuroradiology · 2022Article
- Subject-Specific Studies of CSF Bulk Flow Patterns in the Spinal Canal: Implications for the Dispersion of Solute Particles in Intrathecal Drug Delivery.AJNR. American journal of neuroradiology · 2019Article
Corrections and comments
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Authors and funding
6 authors at 5 institutions in 2 countries.
Funding
Abstract
The monitoring of intracranial pressure (ICP) fluctuations, which is needed in the context of a number of neurological diseases, requires the insertion of pressure sensors, an invasive procedure with considerable risk factors. Intracranial pressure fluctuations drive the wave-like pulsatile motion of cerebrospinal fluid (CSF) along the compliant spinal canal. Systematically derived simplified models relating the ICP fluctuations with the resulting CSF flow rate can be useful in enabling indirect evaluations of the former from non-invasive magnetic resonance imaging (MRI) measurements of the latter. As a preliminary step in enabling these predictive efforts, a model is developed here for the pulsating viscous motion of CSF in the spinal canal, assumed to be a linearly elastic compliant tube of slowly varying section, with a Darcy pressure-loss term included to model the fluid resistance introduced by the
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.