Evidence map›Paper›PMID 36336969›Full record

ArticleInternational wound journal2023

Analysis of curative effect of insulin external application on burn wounds of diabetic patients with different depths.

Meng Yang, Cuikun Li, Xin Xue, Wei Wei, Liang Xing, Jianke Feng, Qingfu Zhang

RetractedOpen access · goldAbstract readRetracted Publication
In one paragraph

Article in International wound journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Meng YangDepartment of Burn and Plastic Surgery, The First Hospital of Hebei Medical University, Shijiazhuang, China.
Cuikun LiDepartment of Burn and Plastic Surgery, The First Hospital of Hebei Medical University, Shijiazhuang, China.ORCID https://orcid.org/0000-0003-1523-4419
Xin XueDepartment of Burn and Plastic Surgery, The First Hospital of Hebei Medical University, Shijiazhuang, China.
Wei WeiDepartment of Burn and Plastic Surgery, The First Hospital of Hebei Medical University, Shijiazhuang, China.
Liang XingDepartment of Burn and Plastic Surgery, The First Hospital of Hebei Medical University, Shijiazhuang, China.
Jianke FengDepartment of Burn and Plastic Surgery, The First Hospital of Hebei Medical University, Shijiazhuang, China.
Qingfu ZhangDepartment of Burn and Plastic Surgery, The First Hospital of Hebei Medical University, Shijiazhuang, China.
Hebei Medical University · CN

Funding

Directive Topic of Hebei Provincial Health Commission 20190038
6 · The paper itself

Abstract

To explore the curative effect of insulin external application on burn wounds of diabetic patients with different depths. A retrospective analysis of 114 diabetic burn patients in the First Hospital of Hebei Medical University from June 2019 to June 2022. According to the different treatment methods, they were divided into study group (insulin therapy) and control group (conventional therapy) with 57 cases in each. The wound healing time, dressing changes, scar healing after wound healing and adverse events were compared between two groups. Pain level, serum inflammatory factors, vascular endothelial growth factor (VEGF) and oxidative stress factors before and after treatment were compared. The wound healing time (17.23 ± 2.18 vs 20.31 ± 2.09 days) and the number of dressing changes (7.01 ± 1.23 vs 8.93 ± 1.32 times) in study group were significantly lower than those in control group (P < 0.05). Before treatment, there was no difference in pain level, VEGF, interleukin-1 (IL-1), tumour necrosis factor-α (TNF-α), malondialdehyde (MDA) and superoxide dismutase (SOD) between two groups (P > 0.05). However, the pain level, scar healing, IL-1, TNF-a and MDA in study group were significantly lower than those in control group after treatment (P < 0.05). And the VEGF and SOD in study group was significantly higher than that in control group (P < 0.05). External application of insulin can shorten the wound healing time of diabetic patients with different depths, reduce the number of dressing changes, promote scar healing after wound healing, relieve pain and reduce the level of inflammatory factors, which is worthy of clinical promotion.

Indexed as

BurnsDiabetes MellitusCicatrixHumansInsulinInterleukin-1Retrospective StudiesSuperoxide DismutaseVascular Endothelial Growth Factor AInsulinInterleukin-1Superoxide DismutaseVascular Endothelial Growth Factor Aburnscurative effectdiabetesinsulin external applicationwound

Identifiers

PMID36336969
PMCPMC10088841
OpenAlexW4308366790

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.