Evidence map›Paper›PMID 36336679›Full record

ArticleBMC pregnancy and childbirth2022

A global study of the association of cesarean rate and the role of socioeconomic status in neonatal mortality rate in the current century.

Abbas Alipour, Sedigheh Hantoushzadeh, Kamran Hessami, Maasoumeh Saleh, Mamak Shariat, Bahareh Yazdizadeh, Sepideh Babaniamansour, Azin Ghamari, Sepehr Aghajanian, Kamyar Moradi and 2 more

Open access · goldAbstract read
In one paragraph

Article in BMC pregnancy and childbirth, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 2 countries.

Abbas AlipourDepartment of Community Medicine, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
Sedigheh HantoushzadehDepartment of Obstetrics and Gynecology, Maternal, Fetal and Neonatal Research Center, Tehran University of Medical Sciences, Valiasr Hospital, Tehran, Iran. hantoushzadeh@tums.ac.ir.
Kamran HessamiMaternal Fetal Care Center, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Maasoumeh SalehDepartment of Obstetrics and Gynecology, Tehran University of Medical Sciences, Shariati Hospital, Tehran, Iran.
Mamak ShariatMaternal, Fetal and Neonatal Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Bahareh YazdizadehDepartment of Epidemiology and Biostatistics, Knowledge Utilization Research Center, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Sepideh BabaniamansourSchool of Medicine, Islamic Azad University of Medical Science, Tehran, Iran.
Azin GhamariGrowth and development research center, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
Sepehr AghajanianDepartment of Community Medicine, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran.
Kamyar MoradiStudent Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Abolfazl Shirdel AbdolmalekiSchool of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Zahra EmamiMaternal, Fetal and Neonatal Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Tehran University of Medical Sciences · IRAlborz University of Medical SciencesChildren's Medical Center · IRHarvard University · USIslamic Azad University Medical Branch of Tehran · IRMazandaran University of Medical Sciences · IRShiraz University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCaesarean section (C/S) rates have significantly increased across the world over the past decades. In the present population-based study, we sought to evaluate the association between C/S and neonatal mortality rates. MATERIAL AND

methodsThis retrospective ecological study included longitudinal data of 166 countries from 2000 to 2015. We evaluated the association between C/S rates and neonatal mortality rate (NMR), adjusting for total fertility rate, human development index (HDI), gross domestic product (GDP) percentage, and maternal age at first childbearing. The examinations were also performed considering different geographical regions as well as regions with different income levels.

resultsThe C/S rate and NMR in the 166 included countries were 19.97% ± 10.56% and 10 ± 10.27 per 1000 live birth, respectively. After adjustment for confounding variables, C/S rate and NMR were found correlated (r = -1.1, p < 0.001). Examination of the relationship between C/S rate and NMR in each WHO region resulted in an inverse correlation in Africa (r = -0.75, p = 0.005), Europe (r = -0.12, p < 0.001), South-East Asia (r = -0.41, p = 0.01), and Western Pacific (r = -0.13, p = 0.02), a direct correlation in America (r = 0.06, p = 0.04), and no correlation in Eastern Mediterranean (r = 0.01, p = 0.88). Meanwhile, C/S rate and NMR were inversely associated in regions with upper-middle (r = -0.15, p < 0.001) and lower-middle (r = -0.24, p < 0.001) income levels, directly associated in high-income regions (r = 0.02, p = 0.001), and not associated in low-income regions (p = 0.13). In countries with HDI below the centralized value of 1 (the real value of 0.9), the correlation between C/S rate and NMR was negative while it was found positive in countries with HDI higher than the mentioned cut-off.

conclusionsThis study indicated that NMR associated with C/S is dependent on various socioeconomic factors such as total fertility rate, HDI, GDP percentage, and maternal age at first childbearing. Further attentions to the socioeconomic status are warranted to minimize the NMR by modifying the C/S rate to the optimum cut-off.

Indexed as

Cesarean SectionInfant MortalityDeveloping CountriesFemaleHumansInfant, NewbornPregnancyRetrospective StudiesSocial ClassSocioeconomic FactorsCaesarean section rateHuman development indexNeonatal mortality

Identifiers

PMID36336679
PMCPMC9639272
OpenAlexW4308317659

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.