Evidence map›Paper›PMID 36336529›Full record

ArticleVaccine2022

A socio-ecological exploration to identify factors influencing the COVID-19 vaccine decision-making process among pregnant and lactating women: Findings from Kenya.

Rupali J Limaye, Alicia Paul, Rachel Gur-Arie, Eleonor Zavala, Clarice Lee, Berhaun Fesshaye, Prachi Singh, Wincate Njagi, Paul Odila, Paul Munyao and 5 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Vaccine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Rupali J LimayeDepartment of International Health, Johns Hopkins University, Bloomberg School of Public Health, Baltimore, MD, USA; International Vaccine Access Center, Johns Hopkins University, Bloomberg School of Public Health, Baltimore, MD, USA; Department of Health, Behavior & Society, Johns Hopkins University, Bloomberg School of Public Health, Baltimore, MD, USA; Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA. Electronic address: rlimaye@jhu.edu.
Alicia PaulInternational Vaccine Access Center, Johns Hopkins University, Bloomberg School of Public Health, Baltimore, MD, USA. Electronic address: apaul17@jhu.edu.
Rachel Gur-ArieBerman Institute of Bioethics, Johns Hopkins University, Bloomberg School of Public Health, Baltimore, MD, USA. Electronic address: rgurari1@jhu.edu.
Eleonor ZavalaDepartment of International Health, Johns Hopkins University, Bloomberg School of Public Health, Baltimore, MD, USA. Electronic address: ezavala1@jhu.edu.
Clarice LeeDepartment of International Health, Johns Hopkins University, Bloomberg School of Public Health, Baltimore, MD, USA. Electronic address: claricelee@jhu.edu.
Berhaun FesshayeDepartment of International Health, Johns Hopkins University, Bloomberg School of Public Health, Baltimore, MD, USA. Electronic address: bfessha1@jhu.edu.
Prachi SinghInternational Vaccine Access Center, Johns Hopkins University, Bloomberg School of Public Health, Baltimore, MD, USA. Electronic address: prachi@jhu.edu.
Wincate NjagiJhpiego, Kenya. Electronic address: Wincate.Murathi@jhpiego.org.
Paul OdilaJhpiego, Kenya. Electronic address: Paul.Odila@jhpiego.org.
Paul MunyaoJhpiego, Kenya. Electronic address: Paul.Munyao@jhpiego.org.
Rosemary NjoguJhpiego, Kenya. Electronic address: Rosemary.Njogu@jhpiego.org.
Stephen MutwiwaJhpiego, Kenya. Electronic address: stephen.mutwiwa@jhpiego.org.
Lisa NoguchiJhpiego, Baltimore, MD, USA. Electronic address: lisa.Noguchi@jhpiego.org.
Christopher MorganJhpiego, Baltimore, MD, USA. Electronic address: christopher.morgan@jhpiego.org.
Ruth KarronDepartment of International Health, Johns Hopkins University, Bloomberg School of Public Health, Baltimore, MD, USA. Electronic address: rkarron@jhu.edu.
Johns Hopkins University · USJohns Hopkins Berman Institute of Bioethics · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The vaccine decision-making process of pregnant and lactating women is complex. Regarding COVID-19, pregnant women are at increased risk for severe disease and poor health outcomes. While pregnant and lactating women were excluded from COVID-19 vaccine trials, available evidence suggests that COVID-19 vaccines are safe and protective during pregnancy. In this study, we used a socio-ecological approach to explore factors influencing the decision-making process for COVID-19 vaccines in pregnant and lactating women in Kenya, for the purpose of informing demand generation strategies. As pregnant and lactating women are influenced by many factors, we conducted 84 in-depth interviews with a variety of stakeholders, including 31 pregnant or lactating women, 20 healthcare workers such as nurses, midwives, doctors, and frontline workers, 25 male family members of pregnant or lactating women, and 8 gatekeepers such as community leaders and faith-based leaders. These individuals were recruited from six communities in Kenya: three urban, and three rural. We applied a grounded theory approach to identify emerging themes and organized emerging themes using the SAGE Vaccine Hesitancy model, which includes three categories of determinants of vaccine acceptance, including contextual influences, individual and group influences, and vaccine and vaccination specific issues. Myths, interpersonal norms, and religion emerged as themes related to contextual influences. Safety, risk perception, and the role of the healthcare worker emerged as themes related to individual and group influences. For vaccine and vaccination specific issues, emerging themes included availability, accessibility, and eligibility. While maternal immunization can substantially reduce the effect of infectious diseases in mothers and infants, vaccine acceptance is critical. However, vaccines do not save lives; vaccination does. We hope the results of this study can be used to tailor communication efforts to increase vaccine demand among pregnant and lactating women.

Indexed as

COVID-19COVID-19 VaccinesFemaleHumansInfantKenyaLactationMaleMothersPregnancyCOVID-19 VaccinesCommunicationCOVID-19Maternal immunizationPregnant womenVaccine acceptance

Identifiers

PMID36336529
PMCPMC9618426
OpenAlexW4308028260

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.