Evidence map›Paper›PMID 36335676›Full record

ArticleClinical imaging2023

Axillary adenopathy detected on breast MRI following COVID-19 vaccination: outcomes and follow-up recommendations.

Derek L Nguyen, Xindi Chen, Lily Kwak, Eniola T Oluyemi, Lisa A Mullen, Emily B Ambinder

Open access · bronzeAbstract read
In one paragraph

Article in Clinical imaging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Vaccination of Adults With Cancer: ASCO Guideline.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2024
    Guideline
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Derek L NguyenJohns Hopkins Medicine, 601 North Caroline St, Baltimore, MD 21287, United States of America. Electronic address: dnguye80@jhmi.edu.
Xindi ChenJohns Hopkins Medicine, 601 North Caroline St, Baltimore, MD 21287, United States of America. Electronic address: xchen220@jhmi.edu.
Lily KwakJohns Hopkins Medicine, 601 North Caroline St, Baltimore, MD 21287, United States of America. Electronic address: lkwak@jhmi.edu.
Eniola T OluyemiJohns Hopkins Medicine, 601 North Caroline St, Baltimore, MD 21287, United States of America. Electronic address: eobadin1@jhmi.edu.
Lisa A MullenJohns Hopkins Medicine, 601 North Caroline St, Baltimore, MD 21287, United States of America. Electronic address: lmullen1@jhmi.edu.
Emily B AmbinderJohns Hopkins Medicine, 601 North Caroline St, Baltimore, MD 21287, United States of America. Electronic address: emcinto8@jhmi.edu.
Johns Hopkins University · USJohns Hopkins Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This retrospective study presents 110 patients with suspected COVID-19 vaccine-related axillary adenopathy on breast MRI. Our study aimed to assess the outcomes of axillary adenopathy detected on breast MRI performed within one year after COVID-19 vaccination. The median time between the COVID-19 vaccine and breast MRI was shorter in patients with detected adenopathy compared to patients without detected adenopathy (6 weeks [2-17] versus 15 [7-24] weeks, p < 0.001). Unilateral axillary adenopathy detected on breast MRI had a low malignancy rate (3.3%), and no cases of malignant axillary adenopathy were diagnosed without a known breast cancer in the ipsilateral breast. Our findings suggest that unilateral axillary adenopathy identified on breast MRI ipsilateral to a recent COVID-19 vaccination can be considered benign in the absence of a suspicious breast finding or known breast cancer. Regardless of vaccine status and timing, unilateral axillary adenopathy detected on MRI evaluation with a known malignancy or suspicious breast finding should be considered suspicious. This will avoid unnecessary scheduling constraints, patient anxiety, and cost, without delaying diagnosis of metastatic breast cancer.

Indexed as

Breast NeoplasmsCOVID-19COVID-19 VaccinesLymphadenopathyAxillaFemaleFollow-Up StudiesHumansLymphatic MetastasisLymph NodesMagnetic Resonance ImagingRetrospective StudiesVaccinationCOVID-19 VaccinesAxillary adenopathyCOVID-19Extent of diseaseVaccination

Identifiers

PMID36335676
PMCPMC9546499
OpenAlexW4303520656

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.