Evidence map›Paper›PMID 36335602›Full record

ArticleJournal of cardiac surgery2022

Endovascular thrombectomy for large vessel occlusion acute ischemic stroke after cardiac surgery.

Aashray K Gupta, Ahad Sabab, Rudy Goh, Christopher D Ovenden, Joshua G Kovoor, Fabio Ramponi, Justin C Y Chan, Benjamin A J Reddi, Jayme S Bennetts, Guy J Maddern and 1 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cardiac surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Aashray K GuptaDiscipline of Surgery, Royal Adelaide Hospital, University of Adelaide, Adelaide, South Australia, Australia.ORCID http://orcid.org/0000-0002-8038-0378
Ahad SababDiscipline of Surgery, Royal Adelaide Hospital, University of Adelaide, Adelaide, South Australia, Australia.
Rudy GohStroke Unit, Royal Adelaide Hospital, Adelaide, South Australia, Australia.
Christopher D OvendenDiscipline of Surgery, Royal Adelaide Hospital, University of Adelaide, Adelaide, South Australia, Australia.
Joshua G KovoorDiscipline of Surgery, Royal Adelaide Hospital, University of Adelaide, Adelaide, South Australia, Australia.
Fabio RamponiDepartment of Cardiothoracic Surgery, Royal Adelaide Hospital, Adelaide, South Australia, Australia.ORCID http://orcid.org/0000-0002-8728-811X
Justin C Y ChanDiscipline of Surgery, Royal Adelaide Hospital, University of Adelaide, Adelaide, South Australia, Australia.
Benjamin A J ReddiIntensive Care Unit, Royal Adelaide Hospital, Adelaide, South Australia, Australia.
Jayme S BennettsCardiothoracic Surgical Unit, Flinders Medical Centre, Adelaide, South Australia, Australia.
Guy J MaddernDiscipline of Surgery, Royal Adelaide Hospital, University of Adelaide, Adelaide, South Australia, Australia.
Timothy J KleinigStroke Unit, Royal Adelaide Hospital, Adelaide, South Australia, Australia.
Royal Adelaide Hospital · AUFlinders Medical Centre · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAcute ischemic stroke (AIS) can be a catastrophic complication of cardiac surgery previously without effective treatment. Endovascular thrombectomy (EVT) is a potentially life-saving intervention. We examined patients at our institution who had EVT to treat AIS post cardiac surgery.

methodsWe retrospectively reviewed a stroke database from January 1, 2016 to October 31, 2021 to identify patients who had undergone EVT to treat AIS following cardiac surgery. Demographic data, operation type, stroke severity, imaging features, management and outcomes (mortality and modified Rankin Score (mRS)) were assessed.

resultsOf 5022 consecutive patients with AIS, 870 underwent EVT. Seven patients (0.8%) had EVT following cardiac surgery. Operations varied: two coronary artery bypass grafting (CABG), two transcatheter AVR, one redo surgical aortic valve replacement (AVR), one mitral valve repair and one patient with combined aortic and mitral valve replacements and CABG. Meantime postsurgery to stroke symptoms onset was 3 days (range 0-9 days). Median NIHSS was 26 (range 10-32). Five patients had middle cerebral artery occlusion and two internal carotid artery (n = 2). Median time between onset of symptoms and recanalization was 157 min (range 97-263). Two patients received Intra-arterial Thrombolysis. All patients survived and were discharged to another hospital (n = 3), home (n = 2), or rehabilitation facility (n = 2). Median 3-month mRS was 3 (range 0-6).

conclusionWe report the largest case series of EVT after cardiac surgery. EVT can be associated with excellent outcomes in these patients. Close neurological monitoring postoperatively to identify patients who may benefit from intervention is key.

Indexed as

Brain IschemiaEndovascular ProceduresIschemic StrokeStrokeCoronary Artery BypassHumansRetrospective StudiesThrombectomyTreatment Outcomecardiovascular pathologycardiovascular researchcoronary artery diseasevalve repair/replacement

Identifiers

PMID36335602
PMCPMC10100038
OpenAlexW4308294037

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.