Evidence map›Paper›PMID 36335146›Full record

ArticleScientific reports2022

High-resolution cortical parcellation based on conserved brain landmarks for localization of multimodal data to the nearest centimeter.

Hari McGrath, Hitten P Zaveri, Evan Collins, Tamara Jafar, Omar Chishti, Sami Obaid, Alexander Ksendzovsky, Kun Wu, Xenophon Papademetris, Dennis D Spencer

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Hari McGrathDepartment of Neurosurgery, Yale School of Medicine, New Haven, CT, USA. hari.mcgrath@yale.edu.
Hitten P ZaveriDepartment of Neurology, Yale School of Medicine, New Haven, CT, USA.
Evan CollinsDepartment of Neurosurgery, Yale School of Medicine, New Haven, CT, USA.
Tamara JafarDepartment of Neurosurgery, Yale School of Medicine, New Haven, CT, USA.
Omar ChishtiDepartment of Neurosurgery, Yale School of Medicine, New Haven, CT, USA.
Sami ObaidDepartment of Neurosurgery, Yale School of Medicine, New Haven, CT, USA.
Alexander KsendzovskyDepartment of Neurosurgery, Yale School of Medicine, New Haven, CT, USA.
Kun WuDepartment of Neurosurgery, Yale School of Medicine, New Haven, CT, USA.
Xenophon PapademetrisDepartment of Radiology and Biomedical Engineering, Yale School of Medicine, New Haven, CT, USA.
Dennis D SpencerDepartment of Neurosurgery, Yale School of Medicine, New Haven, CT, USA.
Yale University · USMassachusetts Institute of Technology · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Network analysis for epilepsy surgeryR01NS109062 · NINDS · YALE UNIVERSITY · PI EID, TORE, ZAVERI, HITTEN P · 2019 to 2022
$1.5M
NCATS NIH HHS UL1 TR001863NINDS NIH HHS R01 NS109062
6 · The paper itself

Abstract

Precise cortical brain localization presents an important challenge in the literature. Brain atlases provide data-guided parcellation based on functional and structural brain metrics, and each atlas has its own unique benefits for localization. We offer a parcellation guided by intracranial electroencephalography, a technique which has historically provided pioneering advances in our understanding of brain structure-function relationships. We used a consensus boundary mapping approach combining anatomical designations in Duvernoy's Atlas of the Human Brain, a widely recognized textbook of human brain anatomy, with the anatomy of the MNI152 template and the magnetic resonance imaging scans of an epilepsy surgery cohort. The Yale Brain Atlas consists of 690 one-square centimeter parcels based around conserved anatomical features and each with a unique identifier to communicate anatomically unambiguous localization. We report on the methodology we used to create the Atlas along with the findings of a neuroimaging study assessing the accuracy and clinical usefulness of cortical localization using the Atlas. We also share our vision for the Atlas as a tool in the clinical and research neurosciences, where it may facilitate precise localization of data on the cortex, accurate description of anatomical locations, and modern data science approaches using standardized brain regions.

Indexed as

BrainNeurosciencesBrain MappingHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingNeuroimaging

Identifiers

PMID36335146
PMCPMC9637135
OpenAlexW4308451218

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.