Evidence map›Paper›PMID 36335102›Full record

ArticleNature communications2022

Structure insights into selective coupling of G protein subtypes by a class B G protein-coupled receptor.

Li-Hua Zhao, Jingyu Lin, Su-Yu Ji, X Edward Zhou, Chunyou Mao, Dan-Dan Shen, Xinheng He, Peng Xiao, Jinpeng Sun, Karsten Melcher and 3 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 32 citations in OpenAlex.

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  8. Allosteric mechanism in the distinctive coupling of GProceedings of the National Academy of Sciences of the United States of America · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 2 countries.

Li-Hua Zhao *The CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China. zhaolihuawendy@simm.ac.cn.ORCID 0000-0002-7175-5174
Jingyu Lin *Department of Physiology, School of Basic Medical Sciences, Shandong University, Jinan, 250012, China.ORCID 0000-0001-8525-4082
Su-Yu Ji *Department of Biophysics and Pathology of Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, 310058, China.
X Edward Zhou *Department of Structural Biology, Van Andel Research Institute, Grand Rapids, MI, 49503, USA.
Chunyou MaoDepartment of Biophysics and Pathology of Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, 310058, China.ORCID 0000-0001-5349-8592
Dan-Dan ShenDepartment of Biophysics and Pathology of Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, 310058, China.ORCID 0000-0001-8757-4602
Xinheng HeThe CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
Peng XiaoDepartment of Physiology, School of Basic Medical Sciences, Shandong University, Jinan, 250012, China.ORCID 0000-0002-9809-3481
Jinpeng SunDepartment of Physiology, School of Basic Medical Sciences, Shandong University, Jinan, 250012, China.ORCID 0000-0003-3572-1580
Karsten MelcherDepartment of Structural Biology, Van Andel Research Institute, Grand Rapids, MI, 49503, USA.
Yan ZhangDepartment of Biophysics and Pathology of Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, 310058, China. zhang_yan@zju.edu.cn.ORCID 0000-0003-2189-0244
Xiao YuDepartment of Physiology, School of Basic Medical Sciences, Shandong University, Jinan, 250012, China. yuxiao@sdu.edu.cn.ORCID 0000-0003-1119-8334
H Eric XuThe CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China. eric.xu@simm.ac.cn.ORCID 0000-0002-6829-8144
Shandong University · CNSir Run Run Shaw Hospital · CNChinese Academy of Sciences · CNVan Andel Institute · USShanghai Institute of Materia Medica · CNZhejiang Chinese Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ability to couple with multiple G protein subtypes, such as G

Indexed as

Heterotrimeric GTP-Binding ProteinsUrocortinsHeterotrimeric GTP-Binding ProteinsUrocortins

Identifiers

PMID36335102
PMCPMC9637140
OpenAlexW4308451478

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.