Evidence map›Paper›PMID 36334168›Full record

ArticleJournal of behavioral medicine2023

Adolescent girls' cardiovascular responses to peer rejection: exploring the impact of early life stress.

Sharon Y Lee, Chrystal Vergara-Lopez, Margaret H Bublitz, Allison E Gaffey, Christina D'Angelo, Laura R Stroud

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of behavioral medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Sharon Y LeeDepartment of Psychiatry and Human Behavior, Warren Alpert Medical School, Brown University, Providence, RI, USA. Sharon_Y_Lee@brown.edu.ORCID 0000-0003-3579-6929
Chrystal Vergara-LopezDepartment of Psychiatry and Human Behavior, Warren Alpert Medical School, Brown University, Providence, RI, USA.
Margaret H BublitzDepartment of Psychiatry and Human Behavior, Warren Alpert Medical School, Brown University, Providence, RI, USA.
Allison E GaffeyYale School of Medicine, Department of Internal Medicine (Cardiovascular Medicine), New Haven, CT, USA.
Christina D'AngeloDepartment of Psychiatry and Human Behavior, Warren Alpert Medical School, Brown University, Providence, RI, USA.
Laura R StroudDepartment of Psychiatry and Human Behavior, Warren Alpert Medical School, Brown University, Providence, RI, USA.
Brown University · USProvidence College · USYale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Tracking and Evaluation CoreU54GM115677 · NIGMS · BROWN UNIVERSITY · PI TOVAR, ALISON · 2016 to 2025
$45.0M
Uncoupling of IL-1 beta and VEGF-A Crosstalk Contributes to Impaired Arteriogenesis Response to Ischemia in Chronic Diabetes MellitusP20GM103652 · NIGMS · OCEAN STATE RESEARCH INSTITUTE, INC. · PI ZHOU, YANG · 2013 to 2022
$21.3M
Project 3: Isolating food insecurity to understand childhood health outcomes and biological mechanisms of riskP20GM139767 · NIGMS · MIRIAM HOSPITAL · PI LAURA R STROUD · 2021 to 2026
$14.6M
HPA & Neural Response to Peer Rejection: Biomarkers of Adolescent Depression RiskR01MH092450 · NIMH · MIRIAM HOSPITAL · PI STROUD, LAURA R · 2011 to 2016
$2.7M
Research Training in Childhood Stress, Trauma, and ResilienceT32HD101392 · NICHD · MIRIAM HOSPITAL · PI PARADE, STEPHANIE HART, STROUD, LAURA R · 2020 to 2024
$1.7M
Stress Response, Cognitive Control & "Real Time" Rumination: Shared Mechanisms Underlying Substance Use and Depression (Administrative Supplement)K08DA045935 · NIDA · MIRIAM HOSPITAL · PI VERGARA-LOPEZ, CHRYSTAL · 2018 to 2022
$861k
NCATS NIH HHS UL1 TR001863NICHD NIH HHS T32 HD101392NIDA NIH HHS K08 DA045935NIGMS NIH HHS P20 GM103652NIGMS NIH HHS P20 GM139767NIGMS NIH HHS U54 GM115677NIMH NIH HHS R01 MH092450
6 · The paper itself

Abstract

Detrimental effects of early life stress on cardiovascular health are evident in adolescence. Cardiovascular reactivity and recovery in response to interpersonal stress may be a mechanism. This study aimed to evaluate if adolescent girls with higher early life stress demonstrated greater cardiovascular reactivity and slower recovery to peer rejection. A sample of 92 adolescent girls (age: M = 13.24) self-reported early life stressors. Systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rate (HR) were continuously measured before, during, and after a laboratory peer rejection paradigm. Counter to hypotheses, adolescent girls with higher early life stress had lower, not higher, HR during the recovery period. Early life stress was not associated with SBP or DBP recovery. Additionally, early life stress was not associated with SBP, DBP, or HR reactivity. Future research is needed to assess if blunted cardiovascular reactivity to interpersonal rejection during adolescence is a mechanism linking early life stress and later cardiovascular disease risk in women.

Indexed as

Cardiovascular SystemStress, PsychologicalAdolescentBlood PressureFemaleHeart RateHumansPeer GroupAdolescentsAdverse childhood experiencesCardiovascular reactivityCardiovascular recoveryEarly life stressPeer rejection

Identifiers

PMID36334168
PMCPMC10160243
OpenAlexW4308256431

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.