Evidence map›Paper›PMID 36334105›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2023

Nuclear medicine in the assessment and prevention of cancer therapy-related cardiotoxicity: prospects and proposal of use by the European Association of Nuclear Medicine (EANM).

Matthias Totzeck, Nicolas Aide, Johann Bauersachs, Jan Bucerius, Panagiotis Georgoulias, Ken Herrmann, Fabien Hyafil, Jolanta Kunikowska, Mark Lubberink, Carmela Nappi and 6 more

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Cardiovascular imaging in cardio-oncology.Japanese journal of radiology · 2024
    Review
  9. Review
  10. Review
  11. Review
  12. The current role of nuclear medicine in breast cancer.The British journal of radiology · 2023
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 14 institutions in 8 countries.

Matthias TotzeckDepartment of Cardiology and Vascular Medicine, West German Heart and Vascular Center Essen, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Nicolas AideNuclear Medicine Department, University Hospital, Caen, France.
Johann BauersachsDepartment of Cardiology and Angiology, Hannover Medical School, Hannover, Germany.
Jan BuceriusDepartment of Nuclear Medicine, University Medicine Göttingen, Georg-August-University Göttingen, Göttingen, Germany.
Panagiotis GeorgouliasDepartment of Nuclear Medicine, Faculty of Medicine, University of Thessaly, University Hospital of Larissa, Larissa, Greece.
Ken HerrmannClinic for Nuclear Medicine, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Fabien HyafilDepartment of Nuclear Medicine, DMU IMAGINA, Georges-Pompidou European Hospital, Assistance-Publique - Hôpitaux de Paris, University of Paris, Paris, France.
Jolanta KunikowskaNuclear Medicine Department, Medical University of Warsaw, Warsaw, Poland.
Mark LubberinkMedical Physics, Uppsala University Hospital, Uppsala, Sweden.
Carmela NappiDepartment of Advanced Biomedical Sciences, University of Naples "Federico II", Naples, Italy.
Tienush RassafDepartment of Cardiology and Vascular Medicine, West German Heart and Vascular Center Essen, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Antti SarasteHeart Center, Turku University Hospital and University of Turku, Turku, Finland.
Roberto SciagraNuclear Medicine Unit, Department of Experimental and Clinical Biomedical Sciences "Mario Serio", University of Florence, Florence, Italy.
Riemer H J A SlartMedical Imaging Center, Department of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Hein VerberneDepartment of Radiology and Nuclear Medicine, Amsterdam UMC, Location AMC, University of Amsterdam, Amsterdam, The Netherlands.
Christoph RischplerClinic for Nuclear Medicine, University Hospital Essen, University of Duisburg-Essen, Essen, Germany. christoph.rischpler@uk-essen.de.ORCID 0000-0002-5545-8487
Essen University Hospital · DEAmsterdam University Medical Centers · NLMedical University of Warsaw · PLMedizinische Hochschule Hannover · DEUniversité de Caen Normandie · FRUniversité Paris Cité · FRUniversity Medical Center Groningen · NLUniversity of Duisburg-Essen · DEUniversity of Florence · ITUniversity of Göttingen · DEUniversity of Naples Federico II · ITUniversity of Thessaly · GRUniversity of Turku · FIUppsala University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiotoxicity may present as (pulmonary) hypertension, acute and chronic coronary syndromes, venous thromboembolism, cardiomyopathies/heart failure, arrhythmia, valvular heart disease, peripheral arterial disease, and myocarditis. Many of these disease entities can be diagnosed by established cardiovascular diagnostic pathways. Nuclear medicine, however, has proven promising in the diagnosis of cardiomyopathies/heart failure, and peri- and myocarditis as well as arterial inflammation. This article first outlines the spectrum of cardiotoxic cancer therapies and the potential side effects. This will be complemented by the definition of cardiotoxicity using non-nuclear cardiovascular imaging (echocardiography, CMR) and biomarkers. Available nuclear imaging techniques are then presented and specific suggestions are made for their application and potential role in the diagnosis of cardiotoxicity.

Indexed as

Antineoplastic AgentsCardiomyopathiesHeart FailureMyocarditisNeoplasmsNuclear MedicineCardiotoxicityHumansAntineoplastic AgentsCancer therapy-related cardiotoxicityCardio-oncologyChemotherapyImmunotherapyNuclear medicinePETRadiotherapySPECT

Identifiers

PMID36334105
PMCPMC9852191
OpenAlexW4308256515

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.