Evidence map›Paper›PMID 36334102›Full record

ArticleEuropean radiology2023

Identification of fibrosis in hypertrophic cardiomyopathy: a radiomic study on cardiac magnetic resonance cine imaging.

Cailing Pu, Xi Hu, Sangying Lv, Yan Wu, Feidan Yu, Wenchao Zhu, Lingjie Zhang, Jingle Fei, Chengbin He, Xiaoli Ling and 2 more

Open access · hybridFull text read
In one paragraph

Article in European radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 26 citations in OpenAlex.

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  13. [Clincial Research Progress in Using Magnetic Resonance Imaging to Assess Myocardial Fibrosis in Hypertrophic Cardiomyopathy].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Cailing PuDepartment of Radiology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, No.3 Qingchun East Road, Hangzhou, 310016, Zhejiang Province, China.
Xi HuDepartment of Radiology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, No.3 Qingchun East Road, Hangzhou, 310016, Zhejiang Province, China.
Sangying LvDepartment of Radiology, Shaoxing People's Hospital, Shaoxing, Zhejiang Province, China.
Yan WuDepartment of Radiology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, No.3 Qingchun East Road, Hangzhou, 310016, Zhejiang Province, China.
Feidan YuDepartment of Radiology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, No.3 Qingchun East Road, Hangzhou, 310016, Zhejiang Province, China.
Wenchao ZhuDepartment of Radiology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, No.3 Qingchun East Road, Hangzhou, 310016, Zhejiang Province, China.
Lingjie ZhangDepartment of Radiology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, No.3 Qingchun East Road, Hangzhou, 310016, Zhejiang Province, China.
Jingle FeiDepartment of Radiology, Lishui Municipal Central Hospital, Lishui, Zhejiang Province, China.
Chengbin HeDepartment of Radiology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, No.3 Qingchun East Road, Hangzhou, 310016, Zhejiang Province, China.
Xiaoli LingDepartment of Radiology, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, Zhejiang Province, China.
Fuyan WangDepartment of Radiology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, No.3 Qingchun East Road, Hangzhou, 310016, Zhejiang Province, China.
Hongjie HuDepartment of Radiology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, No.3 Qingchun East Road, Hangzhou, 310016, Zhejiang Province, China. hongjiehu@zju.edu.cn.ORCID http://orcid.org/0000-0002-9859-5860
Sir Run Run Shaw Hospital · CNAffiliated Hospital of Hangzhou Normal University · CNLishui Central Hospital · CNShaoxing People's Hospital · CN

Funding

National Key Research and Development Program of China 2019YFE0117400National Natural Science Foundation of China 81873908Scientific Research Fund of Zhejiang University XY2021032Scientific Research Fund of Zhejiang University XY2021034
6 · The paper itself

Abstract

objectivesHypertrophic cardiomyopathy (HCM) often requires repeated enhanced cardiac magnetic resonance (CMR) imaging to detect fibrosis. We aimed to develop a practical model based on cine imaging to help identify patients with high risk of fibrosis and screen out patients without fibrosis to avoid unnecessary injection of contrast.

methodsA total of 273 patients with HCM were divided into training and test sets at a ratio of 7:3. Logistic regression analysis was used to find predictive image features to construct CMR model. Radiomic features were derived from the maximal wall thickness (MWT) slice and entire left ventricular (LV) myocardium. Extreme gradient boosting was used to build radiomic models. Integrated models were established by fusing image features and radiomic models. The model performance was validated in the test set and assessed by ROC and calibration curve and decision curve analysis (DCA).

resultsWe established five prediction models, including CMR, R1 (based on the MWT slice), R2 (based on the entire LV myocardium), and two integrated models (I

conclusionsA predictive model that fused image and radiomic features from the entire LV myocardium had good diagnostic performance, robustness, and clinical utility. KEY POINTS: • Hypertrophic cardiomyopathy is prone to fibrosis, requiring patients to undergo repeated enhanced cardiac magnetic resonance imaging to detect fibrosis over their lifetime follow-up. • A predictive model based on the entire left ventricular myocardium outperformed a model based on a slice of the maximal wall thickness. • A predictive model that fused image and radiomic features from the entire left ventricular myocardium had excellent diagnostic performance, robustness, and clinical utility.

Indexed as

Cardiomyopathy, HypertrophicContrast MediaFibrosisGadoliniumHumansMagnetic Resonance ImagingMagnetic Resonance Imaging, CineMagnetic Resonance SpectroscopyMyocardiumPredictive Value of TestsContrast MediaGadoliniumCardiomyopathyFibrosisHypertrophicMachine learningMagnetic resonance imaging

Identifiers

PMID36334102
PMCPMC10017609
OpenAlexW4308254470

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read100
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.