ArticleJournal of applied clinical medical physics2023
Contrast thresholds for detection of various iodine concentrations in subtraction CT and dual-energy CT systems.
Article in Journal of applied clinical medical physics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 4 citations in OpenAlex.
- Evaluation of iodine detection and quantification limits in photon-counting CT-a phantom study.European radiology experimental · 2026Article
- Impact of vessel size, dose levels, and body habitus on iodine quantification in cardiovascular photon-counting computed tomography.The British journal of radiology · 2025Article
- Dual imaging agent for magnetic particle imaging and computed tomography.Nanoscale advances · 2023Article
- Contrast thresholds for detection of various iodine concentrations in subtraction CT and dual-energy CT systems.Journal of applied clinical medical physics · 2023Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo estimate the minimum iodine concentrations detectable in simulated vessels of various diameters for both subtraction computed tomography (CT) and dual-energy CT systems.
methodsFillable tubes (diameters: 1, 3, and 5 mm) were filled with a variety of iodine concentrations (range: 0-20 mg/ml), placed in the center of 28-mm cylindrical rods and surrounded with water. Rods with and without fillable tubes were placed in a 20-cm cylindrical solid-water phantom to simulate administration of iodine in blood vessels. The phantom was scanned with clinical subtraction CT (SCT) and dual-energy CT (DECT) head protocols to assess the detection of minimum iodine concentrations in both systems. The SCT and DECT images were evaluated quantitatively with a MATLAB script to extract regions of interest (ROIs) of each simulated vessel. ROI measurements were used to calculate the limit of detectability (LOD) and signal-to-noise ratio of Rose criteria for the assessment of the contrast thresholds.
resultsBoth SNR
conclusionIn this phantom study, SCT showed the capability to detect lower iodine concentrations compared to DECT. Contrast thresholds varied for vessels of different diameters and the smaller vessels required a higher iodine concentration for detection. Based on this knowledge, radiologists can modify their protocols to increase contrast enhancement.
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