Evidence map›Paper›PMID 36333795›Full record

ArticleBMC nephrology2022

Association of renal function screening frequency with renal function decline in patients with type 2 diabetes: a real-world study in primary health care.

Henry Sundqvist, Eveliina Heikkala, Jari Jokelainen, Giuseppina Russo, Ilona Mikkola, Maria Hagnäs

Open access · goldAbstract read
In one paragraph

Article in BMC nephrology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Henry SundqvistRovaniemi Health Center, Koskikatu 25, 96200, Rovaniemi, Finland.
Eveliina HeikkalaRovaniemi Health Center, Koskikatu 25, 96200, Rovaniemi, Finland.
Jari JokelainenCenter for Life Course Health Research, University of Oulu, P.O Box 8000, FI-90014, Oulu, Finland.
Giuseppina RussoDepartment of Clinical and Experimental Medicine, University of Messina, Messina, Italy.
Ilona Mikkola *Rovaniemi Health Center, Koskikatu 25, 96200, Rovaniemi, Finland.
Maria Hagnäs *Rovaniemi Health Center, Koskikatu 25, 96200, Rovaniemi, Finland. maria.hagnas@rovaniemi.fi.
University of Oulu · FIUniversity of Messina · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo examine the association of the screening frequency of estimated glomerular filtration rate (eGFR) with the substantial reduction in eGFR (≥ 25%) among type 2 diabetes (T2D) patients with normal (eGFR≥60 ml/min/1.73 m

methodsA longitudinal study involving 5104 T2D patients with follow-up period of 6.8 years (1.9 SD) were treated at the Rovaniemi Health Center, Rovaniemi, Finland during 2011-2019. The association between the screening frequency of eGFR (yearly vs. non-yearly) and the substantial reduction in eGFR was studied with logistical models and adjusted with biochemical variables and preventive medications.

resultsAmong the T2D patients with normal kidney function, non-yearly eGFR screening was significantly associated with substantial eGFR reduction in both unadjusted (odds ratio [OR] 3.29, 95% confidence interval [CI] 2.54-4.33) and adjusted models (OR 2.06, 95% CI 1.21-3.73) compared with yearly screening frequency. In the group of patients with impaired kidney function in the unadjusted model, non-yearly eGFR screening was significantly associated with substantial eGFR reduction (OR 2.38, 95% CI 1.30-4.73), but became non-significant after adjustments (OR 1.89, 95% CI 0.61-7.21).

conclusionsThis study underscores the role of regular eGFR screening in the prevention of kidney function decline.

Indexed as

Diabetes Mellitus, Type 2Diabetic NephropathiesRenal InsufficiencyGlomerular Filtration RateHumansKidneyLongitudinal StudiesPrimary Health CareKidney FunctionPrimary Health CareScreening FrequencyType 2 Diabetes

Identifiers

PMID36333795
PMCPMC9636837
OpenAlexW4308192352

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.