Evidence map›Paper›PMID 36333788›Full record

ArticleBMC microbiology2022

iTRAQ-based proteomic analysis of Deinococcus radiodurans in response to

Yuan Gao, Naikang Li, Yanxia Zhou, Zhenpeng Zhang, Yao Zhang, Pengcheng Fan, Hangfan Zhou, Tao Zhang, Lei Chang, Huiying Gao and 5 more

Abstract read
In one paragraph

Article in BMC microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Yuan Gao *Central Laboratory of College of Horticulture, Nanjing Agricultural University, Nanjing, 210095, People's Republic of China.
Naikang Li *State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences Beijing, Research Unit of Proteomics & Research and Development of New Drug of Chinese Academy of Medical Sciences, Institute of Lifeomics, 38 Science Park Road, National Center for Protein Sciences (Beijing), Changping District, Beijing, 102206, People's Republic of China.
Yanxia ZhouState Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences Beijing, Research Unit of Proteomics & Research and Development of New Drug of Chinese Academy of Medical Sciences, Institute of Lifeomics, 38 Science Park Road, National Center for Protein Sciences (Beijing), Changping District, Beijing, 102206, People's Republic of China.
Zhenpeng ZhangState Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences Beijing, Research Unit of Proteomics & Research and Development of New Drug of Chinese Academy of Medical Sciences, Institute of Lifeomics, 38 Science Park Road, National Center for Protein Sciences (Beijing), Changping District, Beijing, 102206, People's Republic of China.
Yao ZhangState Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences Beijing, Research Unit of Proteomics & Research and Development of New Drug of Chinese Academy of Medical Sciences, Institute of Lifeomics, 38 Science Park Road, National Center for Protein Sciences (Beijing), Changping District, Beijing, 102206, People's Republic of China.
Pengcheng FanState Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences Beijing, Research Unit of Proteomics & Research and Development of New Drug of Chinese Academy of Medical Sciences, Institute of Lifeomics, 38 Science Park Road, National Center for Protein Sciences (Beijing), Changping District, Beijing, 102206, People's Republic of China.
Hangfan ZhouState Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences Beijing, Research Unit of Proteomics & Research and Development of New Drug of Chinese Academy of Medical Sciences, Institute of Lifeomics, 38 Science Park Road, National Center for Protein Sciences (Beijing), Changping District, Beijing, 102206, People's Republic of China.
Tao ZhangState Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences Beijing, Research Unit of Proteomics & Research and Development of New Drug of Chinese Academy of Medical Sciences, Institute of Lifeomics, 38 Science Park Road, National Center for Protein Sciences (Beijing), Changping District, Beijing, 102206, People's Republic of China.
Lei ChangState Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences Beijing, Research Unit of Proteomics & Research and Development of New Drug of Chinese Academy of Medical Sciences, Institute of Lifeomics, 38 Science Park Road, National Center for Protein Sciences (Beijing), Changping District, Beijing, 102206, People's Republic of China.
Huiying GaoState Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences Beijing, Research Unit of Proteomics & Research and Development of New Drug of Chinese Academy of Medical Sciences, Institute of Lifeomics, 38 Science Park Road, National Center for Protein Sciences (Beijing), Changping District, Beijing, 102206, People's Republic of China.
Yanchang LiState Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences Beijing, Research Unit of Proteomics & Research and Development of New Drug of Chinese Academy of Medical Sciences, Institute of Lifeomics, 38 Science Park Road, National Center for Protein Sciences (Beijing), Changping District, Beijing, 102206, People's Republic of China.
Xianjiang KangSchool of Life Sciences, Institute of Life Science and Green DevelopmentHebei University and Key Laboratory of Microbial Diversity Research and Application of Hebei Province, 180 East Wusi Road, Baoding, 071002, People's Republic of China.
Qiong XieChina Astronaut Research and Training Center, Beijing, 100094, People's Republic of China. xieqio@sina.com.
Zhitang LyuSchool of Life Sciences, Institute of Life Science and Green DevelopmentHebei University and Key Laboratory of Microbial Diversity Research and Application of Hebei Province, 180 East Wusi Road, Baoding, 071002, People's Republic of China. lzt325@126.com.
Ping XuState Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences Beijing, Research Unit of Proteomics & Research and Development of New Drug of Chinese Academy of Medical Sciences, Institute of Lifeomics, 38 Science Park Road, National Center for Protein Sciences (Beijing), Changping District, Beijing, 102206, People's Republic of China. xuping@ncpsb.org.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDeinococcus radiodurans (D. radiodurans) is best known for its extreme resistance to diverse environmental stress factors, including ionizing radiation (IR), ultraviolet (UV) irradiation, oxidative stress, and high temperatures. Robust DNA repair system and antioxidant system have been demonstrated to contribute to extreme resistance in D. radiodurans. However, practically all studies on the mechanism underlying D. radiodurans's extraordinary resistance relied on the treated strain during the post-treatment recovery lag phase to identify the key elements involved. The direct gene or protein changes of D. radiodurans after stress have not yet been characterized.

resultsIn this study, we performed a proteomics profiling on D. radiodurans right after the heavy ion irradiation treatment, to discover the altered proteins that were quickly responsive to IR in D. radiodurans. Our study found that D. radiodurans shown exceptional resistance to

conclusionsThis study shows how D. radiodurans reacts to exposure to

Indexed as

DeinococcusHeavy IonsAntioxidantsBacterial ProteinsEscherichia coliProteomeProteomicsAntioxidantsBacterial ProteinsProteomeAntioxidation regulationDeinococcus radioduransHeavy ion irradiationiTRAQ quantitative mass spectrometryProteome

Identifiers

PMID36333788
PMCPMC9635210

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.