ArticleBMC cardiovascular disorders2022
Risk factors for ventilator-associated pneumonia due to multi-drug resistant organisms after cardiac surgery in adults.
Article in BMC cardiovascular disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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14 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- Perioperative pulmonary infection prevention and management in adult patients after coronary artery bypass grafting: a summary of best evidence.BMC cardiovascular disorders · 2026Pooled it
- Assessment of the role of handwash basins in the airborne transmission of multi-drug-resistant organisms in clinical and non-clinical settings.The Journal of hospital infection · 2026Article
- Surveillance of bacterial colonization and infection in high-risk neonates admitted to tertiary referral hospital in Indonesia.BMC infectious diseases · 2026Article
- Article
- Adult intensive care unit nosocomial infections related deaths in Jimma medical center: a cause specific cox regression analysis.BMC infectious diseases · 2025Article
- Combined pathogenic characteristics to analyze susceptibility factors of postoperative pneumonia in patients undergoing cardiac surgery.Journal of cardiothoracic surgery · 2025Article
- Machine Learning Based Prediction of Postoperative Acute Kidney Injury Risk in Coronary Artery Bypass Grafting Patients.Clinical interventions in aging · 2025Article
- Independent risk factors and outcomes for ventilator-associated pneumonia due to multidrug-resistant organisms after cardiac valvular surgery.Frontiers in cardiovascular medicine · 2025Article
- Prevalence and risk factors for ventilator-associated pneumonia after cardiac surgery: a systematic review and meta-analysis.Journal of thoracic disease · 2024Article
- A nomogram predicting pneumonia after cardiac surgery: a retrospective modeling study.Journal of cardiothoracic surgery · 2024Article
- Risk factors for neonatal VAP: A retrospective cohort study.Experimental biology and medicine (Maywood, N.J.) · 2023Observational
- Multidrug-resistant bacterial infection in adult patients following cardiac surgery: clinical characteristics and risk factors.BMC cardiovascular disorders · 2023Article
- Nosocomial and Ventilator-associated Pneumonia.Open respiratory archivesReview
- Etiological risk factors for infection in the postoperative period of cardiovascular surgery, integrative review.Revista CuidarteReview
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10 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundVentilator-associated pneumonia (VAP) is one of the most common intensive care unit (ICU)-acquired infections, which can cause multiple adverse events. Due to bacterial mutation and overuse of antimicrobial drugs, multidrug-resistant organisms (MDRO) has become one of the major causes of postoperative VAP infections in cardiac patients. Therefore, this study aims to explore the risk factors for VAP with MDRO following cardiac surgery in adults.
methodsThe clinical data of adult VAP patients following cardiac surgery in the hospital from Jan 2017 to May 2021 were analyzed retrospectively, and the patients were divided into the MDRO VAP group and the non-MDRO VAP group. Univariable and multivariable logistic regression analyses were performed on risk factors in patients with MDRO VAP. The species and drug sensitivity of pathogens isolated from the VAP patients were also analyzed.
resultsA total of 61 VAP cases were involved in this study, with 34 cases in the MDRO VAP group (55.7%) and 27 cases in the non-MDRO VAP group (44.3%). Multivariable logistic regression analysis showed that independent risk factors for MDRO VAP included preoperative creatinine clearance rate (CCR) ≥ 86.6ml, intraoperative cardiopulmonary bypass (CPB) time ≥ 151 min, postoperative acute kidney injury (AKI) and nasal feeding. Gram-negative bacilli were the main pathogens in VAP patients (n = 54, 90.0%), with the highest rate of Acinetobacter baumannii (n = 24, 40.0%). Additionally, patients with MDRO VAP had a significantly longer postoperative intensive care unit (ICU) duration and higher hospitalization costs than non-MDRO VAP patients, but there was no notable difference in the 28-day mortality rate between the two groups.
conclusionBased on implementing measures to prevent VAP, clinicians should pay more attention to patients with kidney disease, longer intraoperative CPB time, and postoperative nasal feeding to avoid MDRO infections.
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