Evidence map›Paper›PMID 36333654›Full record

ArticleBMC cardiovascular disorders2022

Cardiovascular risk factors among people with drug-resistant tuberculosis in Uganda.

Joseph Baruch Baluku, Martin Nabwana, Joanitah Nalunjogi, Winters Muttamba, Ivan Mubangizi, Lydia Nakiyingi, Willy Ssengooba, Ronald Olum, Felix Bongomin, Irene Andia-Biraro and 1 more

Open access · goldAbstract read
In one paragraph

Article in BMC cardiovascular disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Association ofJournal of tropical medicine · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

Joseph Baruch BalukuDivision of Pulmonology, Kiruddu National Referral Hospital, Kampala, Uganda. bbjoe18@gmail.com.
Martin NabwanaMakerere University-John Hopkin's University Collaboration, Kampala, Uganda.
Joanitah NalunjogiMakerere University Lung Institute, Kampala, Uganda.
Winters MuttambaMakerere University Lung Institute, Kampala, Uganda.
Ivan MubangiziDirectorate of programs, Mildmay Uganda, Wakiso, Uganda.
Lydia NakiyingiDepartment of Internal Medicine, School of Medicine, Makerere University College of Health Sciences, Kampala, Uganda.
Willy SsengoobaMakerere University Lung Institute, Kampala, Uganda.
Ronald OlumDepartment of Internal Medicine, St. Francis Hospital, Nsambya, Kampala, Uganda.
Felix BongominDepartment of Medical Microbiology and Immunology, Faculty of Medicine, Gulu University, Gulu, Uganda.
Irene Andia-BiraroDepartment of Internal Medicine, School of Medicine, Makerere University College of Health Sciences, Kampala, Uganda.
William WorodriaMakerere University Lung Institute, Kampala, Uganda.
Makerere University · UGGulu University · UGMildmay Uganda · UGMUJHU Research Collaboration · UGNsambya Hospital · UGUniversity of St Andrews · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTuberculosis (TB) and its risk factors are independently associated with cardiovascular disease (CVD). We determined the prevalence and associations of CVD risk factors among people with drug-resistant tuberculosis (DRTB) in Uganda.

methodsIn this cross-sectional study, we enrolled people with microbiologically confirmed DRTB at four treatment sites in Uganda between July to December 2021. The studied CVD risk factors were any history of cigarette smoking, diabetes mellitus (DM) hypertension, high body mass index (BMI), central obesity and dyslipidaemia. We used modified Poisson regression models with robust standard errors to determine factors independently associated with each of dyslipidaemia, hypertension, and central obesity.

resultsAmong 212 participants, 118 (55.7%) had HIV. Overall, 196 (92.5%, 95% confidence interval (CI) 88.0-95.3) had ≥ 1 CVD risk factor. The prevalence; 95% CI of individual CVD risk factors was: dyslipidaemia (62.5%; 55.4-69.1), hypertension (40.6%; 33.8-47.9), central obesity (39.3%; 32.9-46.1), smoking (36.3%; 30.1-43.1), high BMI (8.0%; 5.0-12.8) and DM (6.5%; 3.7-11.1). Dyslipidaemia was associated with an increase in glycated haemoglobin (adjusted prevalence ratio (aPR) 1.14, 95%CI 1.06-1.22). Hypertension was associated with rural residence (aPR 1.89, 95% CI 1.14-3.14) and previous history of smoking (aPR 0.46, 95% CI 0.21-0.98). Central obesity was associated with increasing age (aPR 1.02, 95%CI 1.00-1.03), and elevated diastolic blood pressure (aPR 1.03 95%CI 1.00-1.06).

conclusionThere is a high prevalence of CVD risk factors among people with DRTB in Uganda, of which dyslipidaemia is the commonest. We recommend integrated services for identification and management of CVD risk factors in DRTB.

Indexed as

Cardiovascular DiseasesDiabetes MellitusDyslipidemiasHypertensionTuberculosis, Multidrug-ResistantCross-Sectional StudiesHeart Disease Risk FactorsHumansObesityObesity, AbdominalPrevalenceRisk FactorsUgandaCardiovascularCholesterolDiabetesHypertensionLipidsMDR TBObesitySmokingTB

Identifiers

PMID36333654
PMCPMC9636825
OpenAlexW4308339850

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.