Evidence map›Paper›PMID 36333523›Full record

ArticleScientific reports2022

Automated imaging-based abdominal organ segmentation and quality control in 20,000 participants of the UK Biobank and German National Cohort Studies.

Turkay Kart, Marc Fischer, Stefan Winzeck, Ben Glocker, Wenjia Bai, Robin Bülow, Carina Emmel, Lena Friedrich, Hans-Ulrich Kauczor, Thomas Keil and 15 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
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  7. Deep learning-derived splenic radiomics, genomics, and coronary artery disease.medRxiv : the preprint server for health sciences · 2024
    Article
  8. MRI of kidney size matters.Magma (New York, N.Y.) · 2024
    Review
  9. Review
  10. Article
  11. Renal MRI: From Nephron to NMR Signal.Journal of magnetic resonance imaging : JMRI · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 17 institutions in 2 countries.

Turkay KartBiomedical Image Analysis Group, Department of Computing, Imperial College London, London, UK.
Marc FischerInstitute of Signal Processing and System Theory, University of Stuttgart, Stuttgart, Germany.
Stefan WinzeckBiomedical Image Analysis Group, Department of Computing, Imperial College London, London, UK.
Ben GlockerBiomedical Image Analysis Group, Department of Computing, Imperial College London, London, UK.
Wenjia BaiBiomedical Image Analysis Group, Department of Computing, Imperial College London, London, UK.
Robin BülowInstitute of Diagnostic Radiology and Neuroradiology, Greifswald University Hospital, Greifswald, Germany.
Carina EmmelInstitute for Medical Informatics, Biometry and Epidemiology, University Hospital Essen, Essen, Germany.
Lena FriedrichDepartment of Diagnostic and Interventional Radiology, University Hospital Augsburg, Augsburg, Germany.
Hans-Ulrich KauczorClinic for Diagnostic and Interventional Radiology, University Hospital Heidelberg, Heidelberg, Germany.
Thomas KeilInstitute of Social Medicine, Epidemiology and Health Economics, Charité - University Medicine Berlin, Berlin, Germany.
Thomas KrönckeDepartment of Diagnostic and Interventional Radiology, University Hospital Augsburg, Augsburg, Germany.
Philipp MayerClinic for Diagnostic and Interventional Radiology, University Hospital Heidelberg, Heidelberg, Germany.
Thoralf NiendorfBerlin Ultrahigh Field Facility (B.U.F.F.), Max-Delbrueck-Center for Molecular Medicine, Berlin, Germany.
Annette PetersInstitute of Epidemiology, German Research Center for Environmental Health, Helmholtz Zentrum München, Neuherberg, Germany.
Tobias PischonMax-Delbrueck-Center for Molecular Medicine, Molecular Epidemiology Research Group, Berlin, Germany.
Benedikt M SchaarschmidtInstitute of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, Essen, Germany.
Börge SchmidtInstitute for Medical Informatics, Biometry and Epidemiology, University Hospital Essen, Essen, Germany.
Matthias B SchulzeDepartment of Molecular Epidemiology, German Institute of Human Nutrition, Nuthetal, Germany.
Lale UmutleInstitute of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, Essen, Germany.
Henry VölzkeInstitute for Community Medicine, Greifswald University Hospital, Greifswald, Germany.
Thomas KüstnerMedical Image and Data Analysis Lab, Department of Radiology, University of Tübingen, Tübingen, Germany.
Fabian BambergDepartment of Radiology, University of Freiburg, Freiburg, Germany.
Bernhard SchölkopfEmpirical Inference Department, Max-Planck Institute for Intelligent Systems, 72076, Tübingen, Germany.
Daniel RueckertBiomedical Image Analysis Group, Department of Computing, Imperial College London, London, UK.
Sergios GatidisBiomedical Image Analysis Group, Department of Computing, Imperial College London, London, UK. sergios.gatidis@tuebingen.mpg.de.
Institute of Group Analysis · GBEssen University Hospital · DEImperial College London · GBInstitut für Medizinische Informatik, Biometrie und Epidemiologie · DEUniversitätsmedizin Greifswald · DEUniversity Hospital Augsburg · DEUniversity of Tübingen · DEBerlin Institute of Health at Charité - Universitätsmedizin Berlin · DEGerman Institute of Human Nutrition · DEHeidelberg University · DEHelmholtz Zentrum München · DEMax Delbrück Center · DEMax Planck Institute for Intelligent Systems · DEUniversity Hospital Heidelberg · DEUniversity of Freiburg · DEUniversity of Stuttgart · DEUniversity of Würzburg · DE

Funding

Deutsche Forschungsgemeinschaft 428219130Medical Research Council MC_PC_17228Medical Research Council MC_QA137853
6 · The paper itself

Abstract

Large epidemiological studies such as the UK Biobank (UKBB) or German National Cohort (NAKO) provide unprecedented health-related data of the general population aiming to better understand determinants of health and disease. As part of these studies, Magnetic Resonance Imaging (MRI) is performed in a subset of participants allowing for phenotypical and functional characterization of different organ systems. Due to the large amount of imaging data, automated image analysis is required, which can be performed using deep learning methods, e. g. for automated organ segmentation. In this paper we describe a computational pipeline for automated segmentation of abdominal organs on MRI data from 20,000 participants of UKBB and NAKO and provide results of the quality control process. We found that approx. 90% of data sets showed no relevant segmentation errors while relevant errors occurred in a varying proportion of data sets depending on the organ of interest. Image-derived features based on automated organ segmentations showed relevant deviations of varying degree in the presence of segmentation errors. These results show that large-scale, deep learning-based abdominal organ segmentation on MRI data is feasible with overall high accuracy, but visual quality control remains an important step ensuring the validity of down-stream analyses in large epidemiological imaging studies.

Indexed as

Biological Specimen BanksImage Processing, Computer-AssistedHumansMagnetic Resonance ImagingQuality ControlUnited Kingdom

Identifiers

PMID36333523
PMCPMC9636393
OpenAlexW4308212273

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.