Evidence map›Paper›PMID 36333154›Full record

ArticleUltrasound in medicine & biology2023

Coherence Metrics for Reader-Independent Differentiation of Cystic From Solid Breast Masses in Ultrasound Images.

Alycen Wiacek, Eniola Oluyemi, Kelly Myers, Emily Ambinder, Muyinatu A Lediju Bell

Abstract read
In one paragraph

Article in Ultrasound in medicine & biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. MixTURE: L1-Norm-Based Mixed Second-Order Continuity in Strain Tensor Ultrasound Elastography.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2024
    Article
  6. Far-focus compound ultrasound imaging with lag-one coherence-based zero-cross factor.Technology and health care : official journal of the European Society for Engineering and Medicine · 2024
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alycen WiacekDepartment of Electrical and Computer Engineering, Johns Hopkins University, Baltimore, Maryland, USA. Electronic address: awiacek@oakland.edu.
Eniola OluyemiDepartment of Radiology and Radiological Science, Johns Hopkins Medicine, Baltimore, Maryland, USA.
Kelly MyersDepartment of Radiology and Radiological Science, Johns Hopkins Medicine, Baltimore, Maryland, USA.
Emily AmbinderDepartment of Radiology and Radiological Science, Johns Hopkins Medicine, Baltimore, Maryland, USA.
Muyinatu A Lediju BellDepartment of Electrical and Computer Engineering, Johns Hopkins University, Baltimore, Maryland, USA; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland, USA; Department of Computer Science, Johns Hopkins University, Baltimore, Maryland, USA.

Funding

Minimizing Uncertainty in Breast Ultrasound Imaging with Real-Time Coherence-Based BeamformingR01EB032960 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI BELL, MUYINATU A. LEDIJU · 2022 to 2025
$1.6M
NIBIB NIH HHS R01 EB032960
6 · The paper itself

Abstract

Traditional breast ultrasound imaging is a low-cost, real-time and portable method to assist with breast cancer screening and diagnosis, with particular benefits for patients with dense breast tissue. We previously demonstrated that incorporating coherence-based beamforming additionally improves the distinction of fluid-filled from solid breast masses, based on qualitative image interpretation by board-certified radiologists. However, variable sensitivity (range: 0.71-1.00 when detecting fluid-filled masses) was achieved by the individual radiologist readers. Therefore, we propose two objective coherence metrics, lag-one coherence (LOC) and coherence length (CL), to quantitatively determine the content of breast masses without requiring reader assessment. Data acquired from 31 breast masses were analyzed. Ideal separation (i.e., 1.00 sensitivity and specificity) was achieved between fluid-filled and solid breast masses based on the mean or median LOC value within each mass. When separated based on mean and median CL values, the sensitivity/specificity decreased to 1.00/0.95 and 0.92/0.89, respectively. The greatest sensitivity and specificity were achieved in dense, rather than non-dense, breast tissue. These results support the introduction of an objective, reader-independent method for automated diagnoses of cystic breast masses.

Indexed as

Breast NeoplasmsMammographyBreast DensityFemaleHumansSensitivity and SpecificityUltrasonographyUltrasonography, MammaryBreast cancerBreast ultrasoundCoherence-based beamformingComplicated cysts

Identifiers

PMID36333154
PMCPMC9712258

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.