Evidence map›Paper›PMID 36332590›Full record

ArticleDrug and alcohol dependence2022

Changes in sexual identity and substance use during young adulthood.

Evan A Krueger, Mykala L Repati, Alyssa F Harlow, Jennifer B Unger, Jungeun Olivia Lee, Eric R Pedersen, Bridgid M Conn, Carolyn Wong, Lindsay E Young, Jessica L Barrington-Trimis and 1 more

Abstract read
In one paragraph

Article in Drug and alcohol dependence, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Sexual identity, child maltreatment, mental health, and substance use among emerging adults aged 18 to 23 years.Canadian journal of public health = Revue canadienne de sante publique · 2025
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Evan A KruegerSchool of Social Work, Tulane University, New Orleans, LA 70112, USA. Electronic address: ekrueger@tulane.edu.
Mykala L RepatiSchool of Social Work, Tulane University, New Orleans, LA 70112, USA.
Alyssa F HarlowDepartment of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA 90032, USA.
Jennifer B UngerDepartment of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA 90032, USA.
Jungeun Olivia LeeSuzanne Dworak-Peck School of Social Work, University of Southern California, Los Angeles, CA 90089, USA.
Eric R PedersenDepartment of Psychiatry and Behavioral Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA 90032, USA.
Bridgid M ConnDepartment of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, CA 90032, USA; Division of Adolescent and Young Adult Medicine, Children's Hospital Los Angeles, Los Angeles, CA 90027, USA.
Carolyn WongDepartment of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, CA 90032, USA; Division of Adolescent and Young Adult Medicine, Children's Hospital Los Angeles, Los Angeles, CA 90027, USA.
Lindsay E YoungAnnenberg School for Communication and Journalism, University of Southern California, Los Angeles, CA 90089, USA.
Jessica L Barrington-TrimisDepartment of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA 90032, USA.
Adam M LeventhalDepartment of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA 90032, USA; Department of Psychology, University of Southern California, Los Angeles, CA 90089, USA.

Funding

USC Tobacco Center of Regulatory ScienceU54CA180905 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Raina Pang · 2018 to 2026
$39.0M
Vaping Nicotine and Cannabis Across Adolescence and Young AdulthoodR01CA229617 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BARRINGTON-TRIMIS, JESSICA LOUISE, LEVENTHAL, ADAM MATTHEW · 2019 to 2024
$4.3M
Tobacco Use Treatment Research for Vulnerable PopulationsK24DA048160 · NIDA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Adam Matthew Leventhal · 2019 to 2026
$1.4M
Understanding Transitions from Vaping to Smoking Across AdolescenceK01DA042950 · NIDA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BARRINGTON-TRIMIS, JESSICA LOUISE · 2017 to 2021
$1.0M
HIV Prevention and CareK99HD094648 · NICHD · UNIVERSITY OF CHICAGO · PI YOUNG, LINDSAY ERIN · 2018 to 2019
$189k
NCI NIH HHS R01 CA229617NCI NIH HHS U54 CA180905NICHD NIH HHS K99 HD094648NIDA NIH HHS K01 DA042950NIDA NIH HHS K24 DA048160
6 · The paper itself

Abstract

backgroundSexual identity is dynamic, and changes in identity (e.g., from heterosexual to lesbian, gay, bisexual, or queer [LGBQ+]) are common during young adulthood. It is not well-understood how sexual identity changes may be associated with substance use risk.

methodsTwo waves of data (baseline: October, 2018-October, 2019; follow-up: May-October, 2020) were used from a prospective cohort of young adults (N = 1896; mean age=21.2). Frequency of past 30-day use and new initiation of five substance use outcomes (alcohol, any tobacco, e-cigarettes, cannabis, illicit drugs) were compared across four groups: consistently heterosexual (N = 1567), consistently LGBQ+ (N = 244), heterosexual to LGBQ+ (N = 65), and LGBQ+ to heterosexual (N = 20).

resultsConsistently LGBQ+ (vs. consistently heterosexual) participants reported greater frequency of past 30-day use of alcohol (aOR=1.34, 95% CI=1.04-1.72), any tobacco products (aOR=1.88, CI=1.34-2.63), e-cigarettes (aOR=1.49, CI=1.01-2.19), cannabis (aOR=1.36, CI=1.01-1.84), and illicit drugs (aOR=2.84, CI=1.77-4.56). Heterosexual to LGBQ+ (vs. consistently heterosexual) participants reported greater frequency of past 30-day use of any tobacco products (aOR=1.87, CI=1.06-3.33) and illicit drugs (aOR=2.48, CI=1.10-5.62), and had greater risk of initiating alcohol (aRR=1.82, CI=1.02-3.25) and cannabis use (aRR=2.90, CI=1.81-4.64). LGBQ+ to heterosexual (vs. consistently LGBQ+) participants reported lower frequency of past 30-day use of alcohol (aOR=0.35, CI=0.14-0.88) and any tobacco products (aOR=0.15, CI=0.03-0.80).

conclusionsIdentifying as LGBQ+ was associated with increased risk for frequent substance use, and newly adopting an LGBQ+ identity was associated with increased risk for new substance use initiation. Prevention and treatment interventions may need to tailor messaging to young people who have newly adopted an LGBQ+ identity.

Indexed as

Electronic Nicotine Delivery SystemsIllicit DrugsSexual and Gender MinoritiesSubstance-Related DisordersAdolescentAdultBisexualityFemaleHeterosexualityHumansProspective StudiesSexual BehaviorYoung AdultIllicit DrugsDisparitiesIdentity changeLGBQ+Sexual identitySubstance useYoung adults

Identifiers

PMID36332590
PMCPMC9994583

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.