Evidence map›Paper›PMID 36332589›Full record

ArticleDrug and alcohol dependence2022

Buprenorphine treatment episode duration, dosage, and concurrent prescribing of benzodiazepines and opioid analgesics: The effects of Medicaid prior authorization policies.

Rachel K Landis, Isaac Opper, Brendan Saloner, Adam J Gordon, Douglas L Leslie, Mark Sorbero, Bradley D Stein

Open access · greenAbstract read
In one paragraph

Article in Drug and alcohol dependence, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Rachel K LandisRAND Corporation, 1200 South Hayes Street, Arlington, VA 22202, USA. Electronic address: rlandis@rand.org.
Isaac OpperRAND Corporation, 1776 Main Street, Santa Monica, CA 90401, USA. Electronic address: iopper@rand.org.
Brendan SalonerDepartment of Health Policy and Management, Johns Hopkins University, 615 N. Wolfe Street, Baltimore, MD 21205, USA. Electronic address: bsaloner@jhu.edu.
Adam J GordonProgram for Addiction Research, Clinical Care, Knowledge and Advocacy (PARCKA), Division of Epidemiology, Department of Internal Medicine, University of Utah School of Medicine, 295 Chipeta Way, Salt Lake City, UT 84132, USA; Informatics, Decision-Enhancement, and Analytic Sciences (IDEAS) Center, VA Salt Lake City Health Care System, Salt Lake City, UT, USA. Electronic address: adam.gordon@hsc.utah.edu.
Douglas L LeslieDepartment of Public Health Sciences and Center for Applied Studies in Health Economics, Penn State College of Medicine, Hershey, PA 17033, USA. Electronic address: dleslie@phs.psu.edu.
Mark SorberoRAND Corporation, 4570 Fifth Avenue, Suite 600, Pittsburgh, PA 15213, USA. Electronic address: sorbero@rand.org.
Bradley D SteinRAND Corporation, 4570 Fifth Avenue, Suite 600, Pittsburgh, PA 15213, USA. Electronic address: stein@rand.org.
RAND Corporation · USJohns Hopkins University · USPennsylvania State University · USVA Salt Lake City Healthcare System · US

Funding

Optimal Methods for Estimating Policy Effect Heterogeneity in Opioid Policy ResearchP50DA046351 · NIDA · RAND CORPORATION · PI BRADLEY D STEIN · 2018 to 2026
$20.8M
Quality of Medication Treatment for Opioid Use Disorder in Medicaid-enrollees: The Effects of State Policies and IntiativesR01DA045800 · NIDA · RAND CORPORATION · PI STEIN, BRADLEY D · 2018 to 2022
$2.9M
NIDA NIH HHS P50 DA046351NIDA NIH HHS R01 DA045800
6 · The paper itself

Abstract

backgroundBuprenorphine is an effective medication for the treatment of opioid use disorder (OUD), but the association between prior authorization policies and quality of care for individuals receiving buprenorphine treatment is not well-understood.

methodsUsing 2006-2013 Medicaid Analytic eXtract (MAX) data from 34 states and the District of Columbia, we identified 294,031 episodes of buprenorphine treatment for OUD among individuals aged 14-64 years. We estimated generalized difference-in-differences models to examine the association between buprenorphine prior authorization policies and changes in buprenorphine treatment quality along four dimensions: (1) duration of at least 180 days, (2) dosage of at least 8 milligrams, and concurrent prescribing of (3) opioid analgesics and (4) benzodiazepines.

resultsBuprenorphine prior authorization policies were associated with an 11-percentage point reduction (p < 0.01) in the likelihood of episodes with a duration of at least 180 days in the first four years after policy implementation. The policy was not associated with changes in effective dosage or concurrent prescribing of opioid analgesics or benzodiazepines.

conclusionsBuprenorphine prior authorization policies were associated with a sizeable and significant reduction in episodes of at least 180 days duration, underscoring the importance of identifying and removing barriers to effective and appropriate OUD care.

Indexed as

BuprenorphineOpioid-Related DisordersAnalgesics, OpioidBenzodiazepinesHumansMedicaidOpiate Substitution TreatmentUnited StatesAnalgesics, OpioidBenzodiazepinesBuprenorphineBuprenorphineOpioidsPrior authorizationQualityTreatment

Identifiers

PMID36332589
PMCPMC10695272
OpenAlexW4306958351

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.