ArticleJCO global oncology2022
Long-Term Outcomes in Survivors of Childhood Cancer: A 30-Year Experience From India.
Article in JCO global oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Physical late effects of treatment among survivors of childhood cancer in low- and middle-income countries: a systematic review.Journal of cancer survivorship : research and practice · 2025Pooled it
- Childhood cancer survivors in India: gender gap in long-term survivorship care.The Lancet regional health. Southeast Asia · 2026Article
- Body composition changes and nutritional challenges in children with acute lymphoblastic leukaemia: Perspectives from low-resource settings.The Indian journal of medical research · 2026Review
- Long term outcomes of the Indian childhood cancer survivorship (C2S) cohort: a multicentre study (2016-2024).The Lancet regional health. Southeast Asia · 2026Article
- Nutritional status at diagnosis and follow-up and its impact on short-term clinical outcome in children with cancer: a real-world report from India.Ecancermedicalscience · 2026Article
- Bridging gaps in oncofertility: evaluation of reproductive dysfunction and fertility assessment in pediatric cancer survivors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Outcomes of Infants and Young Children With CNS Embryonal Tumors Using Pre-Irradiation Chemotherapy: A Decade Long Experience.Cancer medicine · 2025Article
- Review
- Changing paradigms in pediatric cancer care - the contemporary landscape and perspectives for India.Ecancermedicalscience · 2025Review
- Dry-feed Added Quercetin Mitigates Cyclophosphamide-induced Oxidative Stress, Inflammation and Gonadal Fibrosis in Adult Male Rats.Anti-inflammatory & anti-allergy agents in medicinal chemistry · 2025Article
- Long-term Follow-up for Survivors of Childhood Cancer in Saudi Arabia: A Multicenter Cross-Sectional Study.Health services insights · 2025Article
- Cancer survivorship in low- and middle-income countries: challenges, needs, and emerging support strategies.Frontiers in public health · 2025Review
- Self protective health care in childhood cancer survivors from the perspective of survivors, parents, and professionals: a qualitative study.BMC health services research · 2024Article
- Extracapsular Dissection Versus Traditional Parotid Surgery: A Comprehensive Review of Techniques and Outcomes.Cureus · 2024Review
- Perceived vulnerability related to health in cancer post-treated adolescent in Iran: a content analysis.BMC public health · 2024Article
- Knowledge and attitude on childhood cancer survivorship among healthcare trainees: a multicentre study from India.Family medicine and community health · 2024Article
- Optimizing Acetabular Positioning: A Comprehensive Review of Contemporary Strategies in Total Hip Arthroplasty.Cureus · 2024Review
- Childhood cancer survivors: improving our practice today to reduce late, major surgical interventions tomorrow.Translational pediatrics · 2024Article
- Assessment of Metabolic Syndrome and Kidney and Heart Function in Childhood Cancer Survivors.Children (Basel, Switzerland) · 2023Article
- Looking Beyond Toxicities: Other Health-related Morbidities Noted in Childhood Solid Tumor Survivors.Journal of Indian Association of Pediatric SurgeonsArticle
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeDespite an increasing number of survivors of childhood cancer (CCS) in low- and middle-income countries, survivorship care is in its nascent stages. We describe the spectrum of late effects seen, challenges faced, and lessons learnt over three decades of a late effects program in India.
methodsWe describe the demographics and profile of late effects of all CCS survivors enrolled in our After Completion of Treatment Clinic from February 5, 1991 (inception) to February 4, 2021. We analyzed the trends by the decade of diagnosis.
resultsThere were 3,067 CCS survivors, the median age was 18 years (range, 3-57 years), and the median follow-up was 11 years (range, 2-46 years). Two thirds (62.4%) had either no or mild late effects, 480 (15.6%), 497 (16.2%), and 162 (5.3%) had grades 2, 3, and 4 late effects, with 67 deaths reported. Notable late effects were chronic viral hepatitis (7.8%), thyroid dysfunction (7.5%), other endocrine issues (13.6%), psychosocial issues (57%), neurocognitive impairment (4.1%), and metabolic syndrome (4%). The cumulative incidence and severity of late effects showed a consistent decline by the decade of diagnosis. Twenty-two percent of survivors are lost to follow-up.
conclusionSurvivors of childhood cancer treated on contemporary treatment protocols have a significantly lower side-effect profile. Attrition to long-term follow-up and psychosocial issues are significant concerns. Understanding the unique spectrum of late effects and establishing a holistic support system go a long way in ensuring the long-term physical and mental health and psychosocial concerns of childhood cancer survivors in low- and middle-income countries.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.