ArticleScience advances2022
A genomic snapshot of demographic and cultural dynamism in Upper Mesopotamia during the Neolithic Transition.
Article in Science advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 47 citations in OpenAlex.
- Local ancestry inference identifies robust evidence of selection in Neolithic Europe.Molecular biology and evolution · 2026Article
- Mesopotamian ancient DNA reveals Iron Age integration of heterogeneous Bronze Age genetic ancestries following resettlement.Genome biology · 2026Article
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- Exploring matrilocality in history: insights from ancient DNA.Evolutionary human sciences · 2026Article
- Strontium and oxygen isotope analysis reveals changing connections to place and group membership in the world's earliest village societies.Scientific reports · 2025Article
- Local increases in admixture with hunter-gatherers followed the initial expansion of Neolithic farmers across continental Europe.Science advances · 2025Article
- Whole-genome ancestry of an Old Kingdom Egyptian.Nature · 2025Article
- Ancient DNA indicates 3,000 years of genetic continuity in the Northern Iranian Plateau, from the Copper Age to the Sassanid Empire.Scientific reports · 2025Article
- Pre-processing of paleogenomes: mitigating reference bias and postmortem damage in ancient genome data.Genome biology · 2025Article
- Pandora: a tool to estimate dimensionality reduction stability of genotype data.Bioinformatics advances · 2025Article
- Reconstruction of the human amylase locus reveals ancient duplications seeding modern-day variation.Science (New York, N.Y.) · 2024Article
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- The Population History of Domestic Sheep Revealed by Paleogenomes.Molecular biology and evolution · 2024Article
- Interbreeding between farmers and hunter-gatherers along the inland and Mediterranean routes of Neolithic spread in Europe.Nature communications · 2024Article
- READv2: advanced and user-friendly detection of biological relatedness in archaeogenomics.Genome biology · 2024Article
- Palaeogenomic insights into the origins of early settlers on the island of Cyprus.Scientific reports · 2024Article
- The Genetic Origin of the Indo-Europeans.bioRxiv : the preprint server for biology · 2024Article
- Ancient genomes illuminate Eastern Arabian population history and adaptation against malaria.Cell genomics · 2024Article
- Archaeology meets environmental genomics: implementing sedaDNA in the study of the human past.Archaeological and anthropological sciences · 2024Article
Corrections and comments
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Authors and funding
25 authors at 5 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Upper Mesopotamia played a key role in the Neolithic Transition in Southwest Asia through marked innovations in symbolism, technology, and diet. We present 13 ancient genomes (c. 8500 to 7500 cal BCE) from Pre-Pottery Neolithic Çayönü in the Tigris basin together with bioarchaeological and material culture data. Our findings reveal that Çayönü was a genetically diverse population, carrying mixed ancestry from western and eastern Fertile Crescent, and that the community received immigrants. Our results further suggest that the community was organized along biological family lines. We document bodily interventions such as head shaping and cauterization among the individuals examined, reflecting Çayönü's cultural ingenuity. Last, we identify Upper Mesopotamia as the likely source of eastern gene flow into Neolithic Anatolia, in line with material culture evidence. We hypothesize that Upper Mesopotamia's cultural dynamism during the Neolithic Transition was the product not only of its fertile lands but also of its interregional demographic connections.
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