Evidence map›Paper›PMID 36331556›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2022

Impact of COVID-19 on cardiac autonomic function in healthy young adults: potential role of symptomatology and time since diagnosis.

Rachel J Skow, Nicole A Garza, Damsara Nandadeva, Brandi Y Stephens, Alexis N Wright, Ann-Katrin Grotle, Benjamin E Young, Paul J Fadel

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Cardiac autonomic function in young, healthy adults: Influence of race and sex.American journal of physiology. Regulatory, integrative and comparative physiology · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Cardiac autonomic function is preserved in young adults with major depressive disorder.American journal of physiology. Heart and circulatory physiology · 2024
    Article
  8. Review
  9. Similar Patterns of Dysautonomia in Myalgic Encephalomyelitis/Chronic Fatigue and Post-COVID-19 Syndromes.Pathophysiology : the official journal of the International Society for Pathophysiology · 2024
    Article
  10. Article
  11. Sympathetic transduction at rest and during cold pressor test in young healthy non-Hispanic Black and White women.American journal of physiology. Regulatory, integrative and comparative physiology · 2023
    Article
  12. Article
  13. Observational
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Rachel J SkowDepartment of Kinesiology, The University of Texas at Arlington, Arlington, Texas.ORCID 0000-0002-0163-9792
Nicole A GarzaDepartment of Kinesiology, The University of Texas at Arlington, Arlington, Texas.
Damsara NandadevaDepartment of Kinesiology, The University of Texas at Arlington, Arlington, Texas.ORCID 0000-0002-9635-1117
Brandi Y StephensDepartment of Kinesiology, The University of Texas at Arlington, Arlington, Texas.ORCID 0000-0002-1624-8778
Alexis N WrightDepartment of Kinesiology, The University of Texas at Arlington, Arlington, Texas.
Ann-Katrin GrotleDepartment of Kinesiology, The University of Texas at Arlington, Arlington, Texas.ORCID 0000-0003-2990-8744
Benjamin E YoungDepartment of Kinesiology, The University of Texas at Arlington, Arlington, Texas.ORCID 0000-0003-0239-005X
Paul J FadelDepartment of Kinesiology, The University of Texas at Arlington, Arlington, Texas.ORCID 0000-0002-0115-0743
The University of Texas at Arlington · US

Funding

HHS | National Institutes of Health (NIH) R25DK07838
6 · The paper itself

Abstract

Emerging evidence suggests that COVID-19 may affect cardiac autonomic function; however, the limited findings in young adults with COVID-19 have been equivocal. Notably, symptomology and time since diagnosis appear to influence vascular health following COVID-19, but this has not been explored in the context of cardiac autonomic regulation. Therefore, we hypothesized that young adults who had persistent symptoms following COVID-19 would have lower heart rate variability (HRV) and cardiac baroreflex sensitivity (BRS) compared with those who had COVID-19 but were asymptomatic at testing and controls who never had COVID-19. Furthermore, we hypothesized that there would be relationships between cardiac autonomic function measures and time since diagnosis. We studied 27 adults who had COVID-19 and were either asymptomatic (ASYM;

Indexed as

COVID-19Autonomic Nervous SystemBaroreflexBlood PressureFemaleHeartHeart RateHumansYoung Adultautonomic nervous systemcardiac baroreflex sensitivityheart rate variabilitySARS-CoV-2

Identifiers

PMID36331556
PMCPMC9678405
OpenAlexW4308183655

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.