Evidence map›Paper›PMID 36331513›Full record

Trial reportEuropean journal of orthodontics2023

Pain and discomfort during the first week of maxillary expansion using two different expanders: patient-reported outcomes in a randomized controlled trial.

Stina Hansson, Eva Josefsson, Rune Lindsten, Anders Magnuson, Farhan Bazargani

Registry-linked trialOpen access · bronzeAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in European journal of orthodontics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04458506 (Treatment of Unilateral Posterior Cross Bite in the Mixed Dentition; a Randomized Controlled Trial), which is not on this map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04458506 nacompletednot on this map

Treatment of Unilateral Posterior Cross Bite in the Mixed Dentition; a Randomized Controlled Trial

TypeinterventionalSponsorRegion Örebro CountyRan2019 to 2022Enrolled72ConditionsMalocclusion, Maxillary Expansion, Pain ChildrenArmsMaxillary expansion
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Auditory-Perceptual and Acoustic Characteristics of Sibilant and Vowel Sounds in Children with Cleft Palate Undergoing Rapid Palatal Expansion.Folia phoniatrica et logopaedica : official organ of the International Association of Logopedics and Phoniatrics (IALP) · 2026
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Stina HanssonDepartment of Orthodontics, Postgraduate Dental Education Center, Örebro, Sweden.
Eva JosefssonDepartment of Orthodontics, The Institute for Postgraduate Dental Education, Jönköping, Sweden.
Rune LindstenDepartment of Orthodontics, The Institute for Postgraduate Dental Education, Jönköping, Sweden.ORCID 0000-0002-3223-0068
Anders MagnusonClinical Epidemiology and Biostatistics, School of Medical Sciences, Örebro University, Örebro, Sweden.
Farhan BazarganiDepartment of Orthodontics, Postgraduate Dental Education Center, Örebro, Sweden.ORCID 0000-0002-9851-8996
Örebro University · SEJönköping University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundQuad Helix (QH) is the appliance most preferred by orthodontists to correct unilateral posterior crossbite in the early mixed dentition while other orthodontists suggest rapid maxillary expansion (RME) on deciduous teeth in these patients.

objectivesTo evaluate and compare perceived pain intensity, discomfort, functional jaw impairment, and analgesic consumption during the first week of treatment with either RME or QH appliances. TRIAL

designTwo-arm parallel group, two-centre, randomized controlled trial. MATERIAL AND

methodsSeventy-two patients, mean age 9.5 (SD ±0.8) years, with unilateral posterior crossbite requiring maxillary expansion were randomly allocated to either the RME (22 boys, 14 girls) or QH (22 boys, 14 girls) group. Validated questionnaires were used to assess pain intensity, discomfort, jaw function impairment, and analgesic consumption, on the first, fourth, and seventh days after appliance insertion and activation. BLINDING: Due to clinical limitations, only the outcome assessors were blinded to the groups to which the patients were allocated.

resultsSeventy patients completed the questionnaires. Pain from the tongue and chafe from the appliance were significantly higher in the QH group on the first day of treatment (P = 0.003 and P = 0.000, respectively). On the fourth day, the chafe from the appliance was still significantly higher in the QH group (P = 0.007). Speech was affected in both groups on day 1; this impairment continued and was significantly higher in the RME group days 4 and 7. No significant difference in analgesic consumption was found between the groups at any time. The analgesic consumption was highest at day 1 of treatment. HARMS: No harm was observed in any patient. LIMITATIONS: Double blinding was not possible due to the clinical limitations.

conclusionDuring the initial 4 days of treatment, pain from the tongue and chafe from the appliance caused the most reported inconvenience in the patients in the QH group. A majority of reported visual analogue scale values were in the lower mid-range, suggesting low to moderate pain and discomfort in both groups. CLINICAL

trial registrationNCT04458506.

Indexed as

MalocclusionPalatal Expansion TechniqueAnalgesicsChildFemaleHumansMalePainPatient Reported Outcome MeasuresAnalgesics

Identifiers

PMID36331513
PMCPMC10230245
OpenAlexW4308185258

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.