ArticleSkin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)2023
Detection of skin thickness and density in healthy Chinese people by using high-frequency ultrasound.
Article in Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 37 citations in OpenAlex.
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- Development and Surface Indentation Assessment of an MRI-Based Subject-Specific Hand-Forearm Finite Element Model: A Preliminary Study.Bioengineering (Basel, Switzerland) · 2026Article
- Assessing Plantar Skin Epidermal Layer in Response to Various Insole Hardness via Deep Learning Enabled Optical Coherence Tomography Analysis.Journal of biophotonics · 2026Article
- Skin aging: mechanisms, evaluation, and rejuvenation.The EMBO journal · 2026Review
- Finite element modeling of inter-individual variation in soft tissue mechanical response to localized pressure.Biomechanics and modeling in mechanobiology · 2026Article
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- The Influence of Age and Gender on Forehead Soft Tissue Thickness: A Magnetic Resonance Imaging-Based Study.Aesthetic plastic surgery · 2025Article
- Noninvasive Assessment Methods for the Therapeutic Effect Following Facial Rejuvenation.Journal of cosmetic dermatology · 2025Review
- Quantification of normal skin thickness using very high-frequency ultrasound: a clinical study in Chinese adults.Quantitative imaging in medicine and surgery · 2025Article
- Validity and Advantages of Three-Dimensional High-Frequency Ultrasound in Dermatological Evaluation.Diagnostics (Basel, Switzerland) · 2025Article
- High-frequency ultrasound characterization of vulvar skin in patients with lichenoid vulvar dermatoses and correlation of its vascular index with microvessel density and microvessel area.Frontiers in medicine · 2025Article
- Longevity cosmeceuticals as the next frontier in cosmetic innovation: a scientific framework for substantiating product claims.Frontiers in aging · 2025Review
- Comparison of facial skin ageing in healthy Asian and Caucasian females quantified by in vivo line-field confocal optical coherence tomography 3D imaging.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024Article
- Intradermal Treatment with a Hyaluronic Acid Complex Supplemented with Amino Acids and Antioxidant Vitamins Improves Cutaneous Hydration and Viscoelasticity in Healthy Subjects.Antioxidants (Basel, Switzerland) · 2024Article
- Efficacy and Safety of Detachable Microneedle Patch Containing Triamcinolone Acetonide in the Treatment of Inflammatory Acne.Clinical, cosmetic and investigational dermatology · 2023Article
- Detection of skin thickness and density in healthy Chinese people by using high-frequency ultrasound.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2023Article
- The Effects of Subacute Sunlight Exposure on Skin Thickness: A Pilot Sonographic Study.Journal of medical ultrasoundArticle
Corrections and comments
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Authors and funding
12 authors at 7 institutions in 1 country.
Funding
Abstract
objectivesDue to a recent development of high-frequency ultrasound (HFUS) systems, it is easier to realize high-resolution in vivo imaging of the biological tissues. The object of this study was to map the thickness and echo density of skin layers in healthy Chinese people and assess the influence of gender, age, and region on it.
methodsA total of 189 volunteers (85 male, 104 female) with age range of 22-75-year old (mean age of 41.2-year old) were enrolled. The thickness and density of the epidermis and dermis layer were detected by high-frequency (22 or 75 MHz) ultrasonography at 13 different anatomical sites, including the forehead, cheeks, flexor and extensor forearms, flexor and extensor upper arms, inner and outer legs, inner and outer thighs, back, and abdomen.
resultsThe thickness and density of epidermis/dermis between different anatomical sites were statistically significant (p < 0.05). The epidermis thickness of the face and trunk were less than that of the limbs, whereas the thicknesses of the dermis were on the contrary. The density of the epidermis/dermis of the face and trunk were less than that of the limbs. The thickness of dermis in most of the sites were higher in male than in female, and the density of epidermis and dermis in most of the sites were less in men than in women. The thicknesses/densities of dermis were lower in older age group in almost all sites, whereas only several sites reached statistical. The difference between the north and south regions showed the environment also influenced the thickness and density of the skin.
conclusionHFUS provides a simple noninvasive method for evaluating the skin thickness and echo-density, which, reflecting intradermal structure, exhibit systematic regional variation. With the establishment of Chinese phenotypic database of skin thickness and density, it will be helpful for the skin disease assessment, skin surgery, and cosmetology technology.
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