Evidence map›Paper›PMID 36331035›Full record

ArticleVeterinary dermatology2023

Risk factors for meticillin-resistant Staphylococcus aureus (MRSA) carriage in MRSA-exposed household pets.

Caitlin J Cotter, Cusi Ferradas, Shanna Ludwig, Kathryn Dalton, Jesper Larsen, Daniel Laucks, Sally Ann Iverson, Patrick Baron, Pam C Tolomeo, Amy M Brazil and 5 more

Open access · greenAbstract read
In one paragraph

Article in Veterinary dermatology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Molecular Epidemiologic and Geo-Spatial Characterization ofAntibiotics (Basel, Switzerland) · 2023
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 3 countries.

Caitlin J CotterBloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA.ORCID https://orcid.org/0000-0001-5838-6389
Cusi FerradasBloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA.
Shanna LudwigBloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA.
Kathryn DaltonBloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA.
Jesper LarsenDepartment of Bacteria, Parasites and Fungi, Statens Serum Institut, Copenhagen, Denmark.
Daniel LaucksBloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA.
Sally Ann IversonBloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA.
Patrick BaronBloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA.
Pam C TolomeoPerelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Amy M BrazilBloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA.
Jacqueline M FergusonBloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA.
Ebbing LautenbachPerelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Shelley C RankinSchool of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Daniel O MorrisSchool of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Meghan F DavisBloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA.
Johns Hopkins University · USUniversity of Pennsylvania · USDavidson College · USStatens Serum Institut · DK

Funding

Traning Program in Environmental Health SciencesT32ES007141 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI Marsha Wills-Karp · 1985 to 2026
$22.2M
University of California Launching Future Leaders in Global Health Research Training ProgramD43TW009343 · FIC · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CRAIG R COHEN, Sung-Jae Lee · 2017 to 2026
$14.7M
Peru Infectious Diseases Epidemiology Research Training ConsortiumD43TW007393 · FIC · UNIVERSIDAD PERUANA CAYETANO HEREDIA · PI Andres G Lescano · 2005 to 2026
$5.9M
Mentoring and patient-oriented research in antimicrobial resistanceK24AI080942 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI LAUTENBACH, EBBING · 2009 to 2013
$853k
Effects of pest and pet animal microbiota on child microbiota and asthma: a one health studyK01OD019918 · OD · JOHNS HOPKINS UNIVERSITY · PI DAVIS, MEGHAN F. · 2016 to 2020
$621k
CDC HHS FOA#CK16-004FIC NIH HHS 3D43TW007393-10S1FIC NIH HHS D43 TW007393FIC NIH HHS D43 TW009343FIC NIH HHS D43TW009343NIAID NIH HHS K24 AI080942NIEHS NIH HHS ES7141-29NIEHS NIH HHS T32 ES007141NIH HHS K01 OD019918ORIP NIH HHS K01OD019918
6 · The paper itself

Abstract

backgroundHousehold pets can carry meticillin-resistant Staphylococcus aureus (MRSA) introduced to the home by their human companions. Specific factors promoting pet carriage of this pathogen have not been fully elucidated.

objectiveThis study evaluated MRSA cultured from pets and the home environment in households where a human infected with MRSA had been identified, and aimed to determine potential risk factors for pet MRSA carriage. MATERIALS AND

methodsHumans diagnosed with community-associated MRSA (CA-MRSA) skin or soft-tissue infection (SSTI) in the mid-Atlantic United States were identified. One hundred forty-two dogs and cats from 57 affected households were identified of which 134 (94.4%) pets and the household environment were sampled for bacterial culture, PCR confirmation and spa-typing for MRSA strain determination. Samples were obtained 3 months later from 86 pets.

resultsAt baseline, 12 (9.0%) pets carried MRSA. Potential risk factors associated with carriage included pet bed (environmental) MRSA contamination, flea infestation and prior antimicrobial use in the pet. Pets tended to carry human-adapted MRSA strains and spa-types of MRSA isolates cultured from pets were concordant with strains cultured from the home environment in seven of eight homes (87.5%) at baseline. CONCLUSIONS AND CLINICAL RELEVANCE: Results may inform risk-based veterinary clinical recommendations and provide evidence for selective pet testing as a possible alternative to early removal of pets from the homes of humans infected with MRSA. MRSA contamination of the home environment is likely an important risk factor for pet MRSA carriage, and household interventions should be considered to reduce risk of MRSA carriage in exposed pets.

Indexed as

Cat DiseasesDog DiseasesMethicillin-Resistant Staphylococcus aureusStaphylococcal InfectionsAnimalsCarrier StateCatsDogsHumansMethicillinPetsRisk FactorsMethicillinantimicrobial usecommunity-associatedenvironmentmeticillin-resistant Staphylococcus aureus (MRSA)spa typeszoonotic

Identifiers

PMID36331035
PMCPMC11168721
OpenAlexW4308188816

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.