Evidence map›Paper›PMID 36330823›Full record

ArticleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2022

Ongoing toxin-positive diphtheria outbreaks in a federal asylum centre in Switzerland, analysis July to September 2022.

Jacob Kofler, Alban Ramette, Patricia Iseli, Lea Stauber, Jens Fichtner, Sara Droz, Annina Zihler Berner, Anna Bettina Meier, Michelle Begert, Sabine Negri and 4 more

Abstract read
In one paragraph

Article in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Epidemiology and Trends ofOpen forum infectious diseases · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Two diphtheria sub-clusters with autochthonous cases in Germany and Poland within aEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025
    Article
  8. Autochthonous outbreak of respiratory diphtheria caused byEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Outbreak ofEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2023
    Article
  15. Article
  16. Diphtheria in Europe.Public health action · 2023
    Article
  17. Article
  18. Recent outbreak of diphtheria in Pakistan; short communication.Annals of medicine and surgery (2012) · 2023
    Article
  19. Article
  20. Migrant health matters.Nature microbiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jacob KoflerCantonal Medical Office, Health Directorate of the Canton of Bern, Bern, Switzerland.
Alban RametteInstitute for Infectious Diseases, University of Bern, Bern, Switzerland.
Patricia IseliStaff Medical Service, Bern University Hospital and University of Bern, Bern, Switzerland.
Lea StauberInstitute for Infectious Diseases, University of Bern, Bern, Switzerland.
Jens FichtnerCantonal Medical Office, Health Directorate of the Canton of Bern, Bern, Switzerland.
Sara DrozInstitute for Infectious Diseases, University of Bern, Bern, Switzerland.
Annina Zihler BernerInstitute for Infectious Diseases, University of Bern, Bern, Switzerland.
Anna Bettina MeierCantonal Medical Office, Health Directorate of the Canton of Bern, Bern, Switzerland.
Michelle BegertStaff Medical Service, Federal Asylum Center, Bern, Switzerland.
Sabine NegriStaff Medical Service, Federal Asylum Center, Bern, Switzerland.
Anne JachmannCantonal Medical Office, Health Directorate of the Canton of Bern, Bern, Switzerland.
Peter Michael KellerInstitute for Infectious Diseases, University of Bern, Bern, Switzerland.
Cornelia StaehelinDepartment of Infectious Diseases, Bern University Hospital and University of Bern, Bern, Switzerland.
Barbara GrützmacherCantonal Medical Office, Health Directorate of the Canton of Bern, Bern, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two diphtheria outbreaks occurred in a Swiss asylum center from July to October 2022, one is still ongoing. Outbreaks mainly involved minors and included six symptomatic respiratory diphtheria cases requiring antitoxin. Phylogenomic analyses showed evidence of imported and local transmissions of toxigenic strains in respiratory and skin lesion samples. Given the number of cases (n = 20) and the large genetic diversity accumulating in one centre, increased awareness and changes in public health measures are required to prevent and control diphtheria outbreaks.

Indexed as

Corynebacterium diphtheriaeDiphtheriaCorynebacteriumDiphtheria ToxinDisease OutbreaksHumansSwitzerlandDiphtheria ToxinCorynebacterium diphtheriaediphtheriaepidemiologypublic health, genomic sequencing

Identifiers

PMID36330823
PMCPMC9635023

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.