Evidence map›Paper›PMID 36330755›Full record

ArticleJournal of microbiology and biotechnology2022

Agonist (P1) Antibody Converts Stem Cells into Migrating Beta-Like Cells in Pancreatic Islets.

Eun Ji Lee, Seung-Ho Baek, Chi Hun Song, Yong Hwan Choi, Kyung Ho Han

Open access · bronzeAbstract read
In one paragraph

Article in Journal of microbiology and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Technologies for Monoclonal Antibody Discovery and Development.International journal of molecular sciences · 2025
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Eun Ji LeeDepartment of Biological Sciences and Biotechnology, Hannam University, Daejeon 34054, Republic of Korea.
Seung-Ho BaekResearch Center for Bio-based Chemistry, Korea Research Institute of Chemical Technology (KRICT), Ulsan 44429, Republic of Korea.
Chi Hun SongDepartment of Biological Sciences and Biotechnology, Hannam University, Daejeon 34054, Republic of Korea.
Yong Hwan ChoiDepartment of Biological Sciences and Biotechnology, Hannam University, Daejeon 34054, Republic of Korea.
Kyung Ho HanDepartment of Biological Sciences and Biotechnology, Hannam University, Daejeon 34054, Republic of Korea.
Hannam University · KRKorea Research Institute of Chemical Technology · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tissue regeneration is the ultimate treatment for many degenerative diseases, however, repair and regeneration of damaged organs or tissues remains a challenge. Previously, we showed that B1 Ab and H3 Ab induce stem cells to differentiate into microglia and brown adipocyte-like cells, while trafficking to the brain and heart, respectively. Here, we present data showing that another selected agonist antibody, P1 antibody, induces the migration of cells to the pancreatic islets and differentiates human stem cells into beta-like cells. Interestingly, our results suggest the purified P1 Ab induces beta-like cells from fresh, human CD34

Indexed as

Islets of LangerhansAnimalsAntibodiesCell DifferentiationCell MovementHumansMiceStem CellsAntibodiesAntibodybeta-like cellscell differentiationinsulinperiostin (POSTN)

Identifiers

PMID36330755
PMCPMC9843745
OpenAlexW4308180884

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.