Evidence map›Paper›PMID 36330531›Full record

ArticleFrontiers in immunology2022

HIV specific CD8

Rabiah Fardoos, Sarah K Nyquist, Osaretin E Asowata, Samuel W Kazer, Alveera Singh, Abigail Ngoepe, Jennifer Giandhari, Ntombifuthi Mthabela, Dirhona Ramjit, Samita Singh and 16 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 11 citations in OpenAlex.

  1. Trial
  2. Article
  3. CD8Frontiers in immunology · 2026
    Review
  4. Dysbiosis modulates CD8iScience · 2025
    Article
  5. Immuno-cell metabolic changes in HIV-1 infection.Infectious diseases & immunity · 2025
    Review
  6. Article
  7. Article
  8. Distinct SIV-specific CD8Nature immunology · 2024
    Article
  9. Review
  10. An angel or a devil? Current view on the role of CD8Journal of translational medicine · 2024
    Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors at 8 institutions in 4 countries.

Rabiah FardoosAfrica Health Research Institute (AHRI), Durban, South Africa.
Sarah K NyquistInstitute for Medical Engineering & Science, Department of Chemistry, and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, United States.
Osaretin E AsowataAfrica Health Research Institute (AHRI), Durban, South Africa.
Samuel W KazerInstitute for Medical Engineering & Science, Department of Chemistry, and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, United States.
Alveera SinghAfrica Health Research Institute (AHRI), Durban, South Africa.
Abigail NgoepeAfrica Health Research Institute (AHRI), Durban, South Africa.
Jennifer GiandhariKwaZulu-Natal Research Innovation and Sequencing Platform (KRISP), Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa.
Ntombifuthi MthabelaAfrica Health Research Institute (AHRI), Durban, South Africa.
Dirhona RamjitAfrica Health Research Institute (AHRI), Durban, South Africa.
Samita SinghAfrica Health Research Institute (AHRI), Durban, South Africa.
Farina KarimAfrica Health Research Institute (AHRI), Durban, South Africa.
Søren BuusDepartment of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.
Frank AndersonDiscipline of General Surgery, Inkosi Albert Luthuli Central Hospital, University of KwaZulu-Natal, Durban, South Africa.
J Zachary PorterfieldAfrica Health Research Institute (AHRI), Durban, South Africa.
Andile L SibiyaDepartment of Otorhinolaryngology & Head & Neck Surgery, Inkosi Albert Luthuli Central Hospital, University of KwaZulu-Natal, Durban, South Africa.
Rishan BipathDepartment of Otorhinolaryngology, King Edward VIII hospital, University of KwaZulu-Natal, Durban, South Africa.
Kumeshan MoodleyDepartment of Ear Nose and Throat, General Justice Gizenga Mpanza Regional Hospital (Stanger Hospital), University of KwaZulu-Natal, Durban, South Africa.
Warren KuhnDepartment of Otorhinolaryngology & Head & Neck Surgery, Inkosi Albert Luthuli Central Hospital, University of KwaZulu-Natal, Durban, South Africa.
Bonnie BergerComputer Science & Artificial Intelligence Lab and Department of Mathematics, Massachusetts Institute of Technology, Cambridge, MA, United States.
Son NguyenInstitute for Medical Engineering & Science, Department of Chemistry, and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, United States.
Tulio de OliveiraKwaZulu-Natal Research Innovation and Sequencing Platform (KRISP), Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa.
Thumbi Ndung'uAfrica Health Research Institute (AHRI), Durban, South Africa.
Philip GoulderAfrica Health Research Institute (AHRI), Durban, South Africa.
Alex K ShalekInstitute for Medical Engineering & Science, Department of Chemistry, and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, United States.
Alasdair LeslieAfrica Health Research Institute (AHRI), Durban, South Africa.
Henrik N KløverprisAfrica Health Research Institute (AHRI), Durban, South Africa.
Africa Health Research Institute · ZAUniversity of KwaZulu-Natal · ZAMassachusetts Institute of Technology · USUniversity College London · GBRagon Institute of MGH, MIT and Harvard · USStanger Hospital · ZAUniversity of Copenhagen · DKUniversity of Oxford · GB

Funding

Pediatric Adolescent Virus Elimination (PAVE) Martin Delaney CollaboratoryUM1AI164566 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Ann M Chahroudi, Deborah Persaud · 2021 to 2026
$35.5M
Graduate Training in Computational and Systems BiologyT32GM087237 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI BURGE, CHRISTOPHER B · 2009 to 2023
$4.6M
An integrated multiplexed genomic assay for low input clinical samples1U24AI118672 · NIAID · BROAD INSTITUTE, INC. · PI SHALEK, ALEX K · 2015 to 2019
$2.0M
Maximising Cure Potential in Paediatric HIV InfectionR01AI133673 · NIAID · UNIVERSITY OF OXFORD · PI GOULDER, PHILIP J · 2017 to 2021
$1.4M
NIAID NIH HHS R01 AI133673NIAID NIH HHS U24 AI118672NIAID NIH HHS UM1 AI164566NIGMS NIH HHS T32 GM087237Wellcome Trust
6 · The paper itself

Abstract

Lymphoid tissues are an important HIV reservoir site that persists in the face of antiretroviral therapy and natural immunity. Targeting these reservoirs by harnessing the antiviral activity of local tissue-resident memory (T

Indexed as

CD8-Positive T-LymphocytesHIV InfectionsHumansImmunologic MemoryPalatine TonsilReceptors, CXCR5Receptors, CXCR5CD8+ TRM cellsexhaustionHIVnatural HIV controlPD-1tonsils

Identifiers

PMID36330531
PMCPMC9623418
OpenAlexW4306684238

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.