ArticleEuropean heart journal open2022
The risk of cardiovascular diseases after miscarriage, stillbirth, and induced abortion: a systematic review and meta-analysis.
Article in European heart journal open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it.
- European guidelines for hypertension in 2024: a comparison of key recommendations for clinical practice.Nature reviews. Cardiology · 2025Guideline
- Treating Women With Calcified Coronary Arteries Using Intravascular Lithotripsy: Primary Results of the EMPOWER CAD Study.Journal of the Society for Cardiovascular Angiography & Interventions · 2026Article
- Uterine artery hemodynamic parameters as key predictors of missed abortion risk: clinical validation based on a multimodal predictive model.American journal of translational research · 2026Article
- A Review of Traditional and Non-Traditional Cardiovascular Risk Factors in Women.International journal of women's health · 2026Review
- Menopause Hormone Therapy in Women With Cardiovascular Risk Factors or Established Ischemic Heart Disease: A Joint FIGO and WHF Position Paper.Global heart · 2026Review
- Prevalence of Coronary Artery Diseases Among Adult Women Residents of Tehran: A Cross-Sectional Report From Tehran Cohort Study (TeCS).Cardiology research and practice · 2026Article
- Association between multiple complications of pregnancy and risk of cardiovascular disease in a large cohort.International journal of cardiology. Cardiovascular risk and prevention · 2025Article
- Reproductive-associated risk factors and incident coronary heart disease in women: an umbrella review.American heart journal plus : cardiology research and practice · 2025Review
- Women's physical health around live births and pregnancy losses: a longitudinal study.European journal of public health · 2025Article
- Pregnancy Complications and Long-Term Atherosclerotic Cardiovascular Disease Risk.Current atherosclerosis reports · 2025Review
- Association of Female Reproductive Factors with Incident Cardiometabolic Disease: Finding from a European Population-Based Study.Global heart · 2025Article
- Exposure to Ambient Heat and Risk of Spontaneous Abortion: A Case-Crossover Study.Epidemiology (Cambridge, Mass.) · 2024Article
- Measuring EQ-5D-5L utility values in parents who have experienced perinatal death.The European journal of health economics : HEPAC : health economics in prevention and care · 2024Article
- Effects of prior reproductive losses on risk of cardiovascular diseases within six months of a first live birth.International journal of cardiology. Cardiovascular risk and prevention · 2024Article
- Diabetic and hypertensive disorders following early pregnancy loss: a systematic review and meta-analysis.EClinicalMedicine · 2024Review
- Ambient air pollution and rate of spontaneous abortion.Environmental research · 2024Article
- Reproductive factors and cardiometabolic disease among middle-aged and older women: a nationwide study from CHARLS.Frontiers in cardiovascular medicine · 2024Article
- Call for Improved Fourth Trimester Care After Stillbirth.Journal of obstetric, gynecologic, and neonatal nursing : JOGNN · 2024Article
- Ectopic pregnancy, its potential links to dementia risk and interactions with depression: insights from a nationwide cohort study.Frontiers in psychiatry · 2024Article
- Miscarriage, stillbirth, and mortality risk from stroke in women: findings from the PLCO study.Epidemiology and health · 2024Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aims: Miscarriage and stillbirth have been included in cardiovascular disease (CVD) risk guidelines, however heterogeneity in exposures and outcomes and the absence of reviews assessing induced abortion, prevented comprehensive assessment. We aimed to perform a systematic review and meta-analysis of the risk of cardiovascular diseases for women with prior pregnancy loss (miscarriage, stillbirth, and induced abortion). Methods and results: Observational studies reporting risk of CVD, coronary heart disease (CHD), and stroke in women with pregnancy loss were selected after searching MEDLINE, Scopus, CINAHL, Web of Knowledge, and Cochrane Library (to January 2020). Data were extracted, and study quality were assessed using the Newcastle-Ottawa Scale. Pooled relative risk (RR) and 95% confidence intervals (CIs) were calculated using inverse variance weighted random-effects meta-analysis.Twenty-two studies involving 4 337 683 women were identified. Seven studies were good quality, seven were fair and eight were poor. Recurrent miscarriage was associated with a higher CHD risk (RR = 1.37, 95% CI: 1.12-1.66). One or more stillbirths was associated with a higher CVD (RR = 1.41, 95% CI: 1.09-1.82), CHD (RR = 1.51, 95% CI: 1.04-1.29), and stroke risk (RR = 1.33, 95% CI: 1.03-1.71). Recurrent stillbirth was associated with a higher CHD risk (RR = 1.28, 95% CI: 1.18-1.39). One or more abortions was associated with a higher CVD (RR = 1.04, 95% CI: 1.02-1.07), as was recurrent abortion (RR = 1.09, 95% CI: 1.05-1.13). Conclusion: Women with previous pregnancy loss are at a higher CVD, CHD, and stroke risk. Early identification and risk factor management is recommended. Further research is needed to understand CVD risk after abortion.
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