Evidence map›Paper›PMID 36330234›Full record

ArticleDEN open2023

Current practice of colonoscopy surveillance in patients with lynch syndrome: A multicenter retrospective cohort study in Japan.

Yasuyuki Miyakura, Akiko Chino, Kohji Tanakaya, Alan Kawarai Lefor, Kiwamu Akagi, Akinari Takao, Masayoshi Yamada, Hideyuki Ishida, Koji Komori, Kazuhito Sasaki and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in DEN open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Yasuyuki MiyakuraDepartment of Surgery Saitama Medical Center Jichi Medical University Saitama Japan.ORCID https://orcid.org/0000-0002-4464-2465
Akiko ChinoThe Committee of Hereditary Colorectal Cancer, Japanese Society for Cancer of the Colon and Rectum Tokyo Japan.
Kohji TanakayaThe Committee of Hereditary Colorectal Cancer, Japanese Society for Cancer of the Colon and Rectum Tokyo Japan.
Alan Kawarai LeforDepartment of Surgery Jichi Medical University Tochigi Japan.ORCID https://orcid.org/0000-0001-6673-5630
Kiwamu AkagiThe Committee of Hereditary Colorectal Cancer, Japanese Society for Cancer of the Colon and Rectum Tokyo Japan.
Akinari TakaoThe Committee of Hereditary Colorectal Cancer, Japanese Society for Cancer of the Colon and Rectum Tokyo Japan.
Masayoshi YamadaThe Committee of Hereditary Colorectal Cancer, Japanese Society for Cancer of the Colon and Rectum Tokyo Japan.
Hideyuki IshidaThe Committee of Hereditary Colorectal Cancer, Japanese Society for Cancer of the Colon and Rectum Tokyo Japan.
Koji KomoriThe Committee of Hereditary Colorectal Cancer, Japanese Society for Cancer of the Colon and Rectum Tokyo Japan.
Kazuhito SasakiThe Committee of Hereditary Colorectal Cancer, Japanese Society for Cancer of the Colon and Rectum Tokyo Japan.
Masashi MiguchiThe Committee of Hereditary Colorectal Cancer, Japanese Society for Cancer of the Colon and Rectum Tokyo Japan.
Keiji HirataThe Committee of Hereditary Colorectal Cancer, Japanese Society for Cancer of the Colon and Rectum Tokyo Japan.
Tomoya SudoThe Committee of Hereditary Colorectal Cancer, Japanese Society for Cancer of the Colon and Rectum Tokyo Japan.
Toshiaki IshikawaThe Committee of Hereditary Colorectal Cancer, Japanese Society for Cancer of the Colon and Rectum Tokyo Japan.
Tatsuro YamaguchiThe Committee of Hereditary Colorectal Cancer, Japanese Society for Cancer of the Colon and Rectum Tokyo Japan.
Naohiro TomitaThe Committee of Hereditary Colorectal Cancer, Japanese Society for Cancer of the Colon and Rectum Tokyo Japan.
Yoichi AjiokaJapanese Society for Cancer of Colon and Rectum Tokyo Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Colonoscopy surveillance reduces the incidence of colorectal cancer through the detection and endoscopic removal of adenomas. Current guidelines recommend that patients with Lynch syndrome should have colonoscopy surveillance every 1-2 years starting at the age of 20-25. However, insufficient data are available to evaluate the quality and safety of colonoscopy surveillance for patients with Lynch syndrome nationwide in Japan. Methods: Patients with Lynch syndrome ( Results: The colonoscopy completion rate was 98.8% and a history of previous colorectal cancer surgery was significantly associated with a higher completion rate. All complications were associated with endoscopic treatment and the rate of bleeding needing hemostasis and perforation needing surgical repair were both 0.16% after colonoscopy with polypectomy. The adenoma detection rate at the first colonoscopy was 25%. Although there was no difference in the completion and complication rates based on differences in the colonoscopy experience of the endoscopist, the detection rate of adenomas and intramucosal cancers was significantly higher with more experienced endoscopists. The proportion of patients developing cancer was significantly higher with a >24 months than a ≤24 months interval. Conclusion: High-volume experienced endoscopists and appropriate surveillance intervals may minimize the risk of developing colorectal cancers in patients with Lynch syndrome.

Indexed as

adenoma detection ratecolonoscopy surveillancecomplicationendoscopic intervalLynch syndrome

Identifiers

PMID36330234
PMCPMC9624071

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.