Evidence map›Paper›PMID 36330228›Full record

ArticleAdvances and applications in bioinformatics and chemistry : AABC2022

Antibacterial and Antioxidant Activities, in silico Molecular Docking, ADMET and DFT Analysis of Compounds from Roots of

Teshome Degfie, Japheth O Ombito, Taye B Demissie, Rajalakshmanan Eswaramoorthy, Aman Dekebo, Milkyas Endale

Abstract read
In one paragraph

Article in Advances and applications in bioinformatics and chemistry : AABC, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Teshome DegfieDepartment of Applied Chemistry, School of Applied Natural Science, Adama Science and Technology University, Adama, Ethiopia.
Japheth O OmbitoDepartment of Chemistry, University of Botswana, Gaborone, Botswana.
Taye B DemissieDepartment of Chemistry, University of Botswana, Gaborone, Botswana.
Rajalakshmanan EswaramoorthyDepartment of Biomaterials, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India.ORCID 0000-0002-8331-2100
Aman DekeboDepartment of Applied Chemistry, School of Applied Natural Science, Adama Science and Technology University, Adama, Ethiopia.
Milkyas EndaleDepartment of Applied Chemistry, School of Applied Natural Science, Adama Science and Technology University, Adama, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Methods: Silica gel column chromatographic separation was used for isolation. 1D and 2D NMR spectroscopic analysis and literature data were used for structural elucidation. Agar well diffusion assay was used for evaluation of antibacterial activity against Results: Dichloromethane/methanol (1:1) roots extract afforded a new hydroxyl-spongiane diterpenoid lactone derivative, 3-hydroxyisoagatholactone ( Conclusion: In this work, eight compounds were identified from the roots extracts of

Indexed as

3-hydroxyisoagatolactoneantibacterialantioxidant studiesCyphostemma cyphopetalumdockingdrug-likeness

Identifiers

PMID36330228
PMCPMC9624657

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.