Evidence map›Paper›PMID 36330045›Full record

ArticleSynthesis2022

Selective Csp

Kaluvu Balaraman, Samantha Kyriazakos, Rachel Palmer, F Yushra Thanzeel, Christian Wolf

Abstract read
In one paragraph

Article in Synthesis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Synthetic Advantages of Defluorinative C-F Bond Functionalization.Angewandte Chemie (International ed. in English) · 2023
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kaluvu BalaramanGeorgetown University, Chemistry Department, Washington, DC 20057, USA.
Samantha KyriazakosGeorgetown University, Chemistry Department, Washington, DC 20057, USA.
Rachel PalmerGeorgetown University, Chemistry Department, Washington, DC 20057, USA.
F Yushra ThanzeelGeorgetown University, Chemistry Department, Washington, DC 20057, USA.
Christian WolfGeorgetown University, Chemistry Department, Washington, DC 20057, USA.

Funding

Synthesis of Chiral Organofluorines via Catalytic Asymmetric C-C Bond Formation wR15GM106260 · NIGMS · GEORGETOWN UNIVERSITY · PI Christian Wolf · 2013 to 2026
$2.2M
NIGMS NIH HHS R15 GM106260
6 · The paper itself

Abstract

A highly efficient method for C-F bond functionalization of a broad variety of activated and unactivated aliphatic substrates with inexpensive lithium iodide is presented. Primary, secondary, tertiary, benzylic, propargylic and α-functionalized alkyl fluorides react in chlorinated or aromatic solvents at room temperature or upon heating to the corresponding iodides which are isolated in 91-99% yield. The reaction is selective for aliphatic monofluorides and can be coupled with

Indexed as

alkyl fluoridesC-F bond functionalizationhalide exchangelithium iodidenucleophilic substitution

Identifiers

PMID36330045
PMCPMC9624501

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.